Pityriasis Rubra Pilar and hypothyroidism

Detalhes bibliográficos
Autor(a) principal: Franzotti,Aline Martinez
Data de Publicação: 2014
Outros Autores: Avelar,Juliana Centofanti Dentello, Cardoso,Thaís Abrão, Pires,Mario Cesar, Vidigal,Maria do Rosário
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000300497
Resumo: Pityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder. Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of several doubts regarding its etiology and also because of its relative rarity, making randomized studies difficult to perform. Some factors suggest that the metabolism of vitamin A is involved in pathogenesis. We report a case of Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which presented rapid and complete response after thyroid hormone replacement, without any association with other systemic treatment. In literature there are only three other reports of significant improvement of the lesions after hormonal correction. Deficiency of thyroid hormone inhibits the conversion of carotene into vitamin A, which would be responsible for the occurrence of Pityriasis Rubra Pilaris in this patient.
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spelling Pityriasis Rubra Pilar and hypothyroidismHypothyroidismPityriasis rubra pilarisTherapeuticsPityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder. Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of several doubts regarding its etiology and also because of its relative rarity, making randomized studies difficult to perform. Some factors suggest that the metabolism of vitamin A is involved in pathogenesis. We report a case of Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which presented rapid and complete response after thyroid hormone replacement, without any association with other systemic treatment. In literature there are only three other reports of significant improvement of the lesions after hormonal correction. Deficiency of thyroid hormone inhibits the conversion of carotene into vitamin A, which would be responsible for the occurrence of Pityriasis Rubra Pilaris in this patient.Sociedade Brasileira de Dermatologia2014-06-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000300497Anais Brasileiros de Dermatologia v.89 n.3 2014reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20142994info:eu-repo/semantics/openAccessFranzotti,Aline MartinezAvelar,Juliana Centofanti DentelloCardoso,Thaís AbrãoPires,Mario CesarVidigal,Maria do Rosárioeng2015-10-19T00:00:00Zoai:scielo:S0365-05962014000300497Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-10-19T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Pityriasis Rubra Pilar and hypothyroidism
title Pityriasis Rubra Pilar and hypothyroidism
spellingShingle Pityriasis Rubra Pilar and hypothyroidism
Franzotti,Aline Martinez
Hypothyroidism
Pityriasis rubra pilaris
Therapeutics
title_short Pityriasis Rubra Pilar and hypothyroidism
title_full Pityriasis Rubra Pilar and hypothyroidism
title_fullStr Pityriasis Rubra Pilar and hypothyroidism
title_full_unstemmed Pityriasis Rubra Pilar and hypothyroidism
title_sort Pityriasis Rubra Pilar and hypothyroidism
author Franzotti,Aline Martinez
author_facet Franzotti,Aline Martinez
Avelar,Juliana Centofanti Dentello
Cardoso,Thaís Abrão
Pires,Mario Cesar
Vidigal,Maria do Rosário
author_role author
author2 Avelar,Juliana Centofanti Dentello
Cardoso,Thaís Abrão
Pires,Mario Cesar
Vidigal,Maria do Rosário
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Franzotti,Aline Martinez
Avelar,Juliana Centofanti Dentello
Cardoso,Thaís Abrão
Pires,Mario Cesar
Vidigal,Maria do Rosário
dc.subject.por.fl_str_mv Hypothyroidism
Pityriasis rubra pilaris
Therapeutics
topic Hypothyroidism
Pityriasis rubra pilaris
Therapeutics
description Pityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder. Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of several doubts regarding its etiology and also because of its relative rarity, making randomized studies difficult to perform. Some factors suggest that the metabolism of vitamin A is involved in pathogenesis. We report a case of Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which presented rapid and complete response after thyroid hormone replacement, without any association with other systemic treatment. In literature there are only three other reports of significant improvement of the lesions after hormonal correction. Deficiency of thyroid hormone inhibits the conversion of carotene into vitamin A, which would be responsible for the occurrence of Pityriasis Rubra Pilaris in this patient.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000300497
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962014000300497
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20142994
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.89 n.3 2014
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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