Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012 |
Resumo: | PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects. |
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Acta Cirúrgica Brasileira (Online) |
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Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative studyBiocompatible MaterialsBone TransplantationCastor OilRabbitsPURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012Acta Cirúrgica Brasileira v.21 n.5 2006reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502006000500012info:eu-repo/semantics/openAccessMendonça,José Carlos Garcia deDe Rossi,RafaelInouye,Celso MassaschiBazan,Diego Rodrigo PaulilloMonteiro,João Carlos CastroMendonça,Juliana Pedroso deeng2007-05-11T00:00:00Zoai:scielo:S0102-86502006000500012Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2007-05-11T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
spellingShingle |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study Mendonça,José Carlos Garcia de Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
title_short |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_full |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_fullStr |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_full_unstemmed |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_sort |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
author |
Mendonça,José Carlos Garcia de |
author_facet |
Mendonça,José Carlos Garcia de De Rossi,Rafael Inouye,Celso Massaschi Bazan,Diego Rodrigo Paulillo Monteiro,João Carlos Castro Mendonça,Juliana Pedroso de |
author_role |
author |
author2 |
De Rossi,Rafael Inouye,Celso Massaschi Bazan,Diego Rodrigo Paulillo Monteiro,João Carlos Castro Mendonça,Juliana Pedroso de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Mendonça,José Carlos Garcia de De Rossi,Rafael Inouye,Celso Massaschi Bazan,Diego Rodrigo Paulillo Monteiro,João Carlos Castro Mendonça,Juliana Pedroso de |
dc.subject.por.fl_str_mv |
Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
topic |
Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
description |
PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-86502006000500012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.21 n.5 2006 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126438195068928 |