Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study

Detalhes bibliográficos
Autor(a) principal: Mendonça,José Carlos Garcia de
Data de Publicação: 2006
Outros Autores: De Rossi,Rafael, Inouye,Celso Massaschi, Bazan,Diego Rodrigo Paulillo, Monteiro,João Carlos Castro, Mendonça,Juliana Pedroso de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012
Resumo: PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.
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spelling Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative studyBiocompatible MaterialsBone TransplantationCastor OilRabbitsPURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012Acta Cirúrgica Brasileira v.21 n.5 2006reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502006000500012info:eu-repo/semantics/openAccessMendonça,José Carlos Garcia deDe Rossi,RafaelInouye,Celso MassaschiBazan,Diego Rodrigo PaulilloMonteiro,João Carlos CastroMendonça,Juliana Pedroso deeng2007-05-11T00:00:00Zoai:scielo:S0102-86502006000500012Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2007-05-11T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
spellingShingle Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
Mendonça,José Carlos Garcia de
Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
title_short Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_full Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_fullStr Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_full_unstemmed Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_sort Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
author Mendonça,José Carlos Garcia de
author_facet Mendonça,José Carlos Garcia de
De Rossi,Rafael
Inouye,Celso Massaschi
Bazan,Diego Rodrigo Paulillo
Monteiro,João Carlos Castro
Mendonça,Juliana Pedroso de
author_role author
author2 De Rossi,Rafael
Inouye,Celso Massaschi
Bazan,Diego Rodrigo Paulillo
Monteiro,João Carlos Castro
Mendonça,Juliana Pedroso de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mendonça,José Carlos Garcia de
De Rossi,Rafael
Inouye,Celso Massaschi
Bazan,Diego Rodrigo Paulillo
Monteiro,João Carlos Castro
Mendonça,Juliana Pedroso de
dc.subject.por.fl_str_mv Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
topic Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
description PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.
publishDate 2006
dc.date.none.fl_str_mv 2006-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502006000500012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.21 n.5 2006
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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