Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFMS |
Texto Completo: | https://repositorio.ufms.br/handle/123456789/141 |
Resumo: | PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects. |
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2011-07-14T14:27:48Z2021-09-30T19:55:52Z2006MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012.https://repositorio.ufms.br/handle/123456789/14110.1590/S0102-86502006000500012PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.OBJETIVO: Estudo morfológico comparativo do implante de poliuretana de mamona e enxerto ósseo autógeno em defeito ósseo padrão em osso zigomático de coelhos. MÉTODOS: Vinte e quatro coelhos Nova Zelândia, machos, adultos, foram distribuídos aleatoriamente em dois grupos de 12. Defeitos de 5mm de diâmetro, perenes, foram confeccionados em osso zigomático e preenchidos com discos pré-fabricados de poliuretana no grupo experimento ou osso autógeno extraído da tíbia no grupo controle. Os animais foram sacrificados após 30, 60 e 90 dias e as peças anatômicas foram avaliadas macro e microscopicamente. Foram utilizados os testes de Student, Fisher,qui-quadrado e McNemar para a análise estatística dos resultados. RESULTADOS: A poliuretana e o osso autógeno se adaptaram ao defeito sem necessidade de fixação. Houve formação de tecido conjuntivo fibroso envolvendo a poliuretana, sem reação inflamatória ou presença de células gigantes. Verificaram-se áreas acidófilas e basófilas nos poros do material implantado, sugestivas de núcleos celulares. No grupo controle, observou-se aos 90 dias o reparo ósseo de padrão lamelar clássico. CONCLUSÃO: A poliuretana de mamona foi biocompatível e não causou reação inflamatória deletéria. Pode ser uma alternativa para o preenchimento de defeitos ósseos.engActa Cirurgica BrasileiraMateriais BiocompatíveisTransplante ÓsseoÓleo de RícinoCoelhosBiocompatible MaterialsBone TransplantationCastor OilRabbitsMorphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative studyEstudo morfológico comparativo do enxerto ósseo autógeno e polímero de mamona em rebordo infra-orbitário de coelhosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMendonça, José Carlos Garcia deRossi, Rafael deInouye, Celso MassaschiBazan, Diego Rodrigo PaulilloMonteiro, João Carlos CastroMendonça, Juliana Pedroso deinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMSinstname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSTHUMBNAILMorphology of autogenous.pdf.jpgMorphology of autogenous.pdf.jpgGenerated Thumbnailimage/jpeg1675https://repositorio.ufms.br/bitstream/123456789/141/4/Morphology%20of%20autogenous.pdf.jpg8ddf5bde587e29d66d3b3d158def1ac2MD54ORIGINALMorphology of autogenous.pdfMorphology of autogenous.pdfapplication/pdf315618https://repositorio.ufms.br/bitstream/123456789/141/1/Morphology%20of%20autogenous.pdf02d84bc75eaef05e48aa2b0ba735a837MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufms.br/bitstream/123456789/141/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTMorphology of autogenous.pdf.txtMorphology of autogenous.pdf.txtExtracted texttext/plain26356https://repositorio.ufms.br/bitstream/123456789/141/3/Morphology%20of%20autogenous.pdf.txt84bff2e567aca52f774357203c537237MD53123456789/1412021-09-30 15:55:52.346oai:repositorio.ufms.br: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Repositório InstitucionalPUBhttps://repositorio.ufms.br/oai/requestri.prograd@ufms.bropendoar:21242021-09-30T19:55:52Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)false |
dc.title.pt_BR.fl_str_mv |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
dc.title.alternative.pt_BR.fl_str_mv |
Estudo morfológico comparativo do enxerto ósseo autógeno e polímero de mamona em rebordo infra-orbitário de coelhos |
title |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
spellingShingle |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study Mendonça, José Carlos Garcia de Materiais Biocompatíveis Transplante Ósseo Óleo de Rícino Coelhos Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
title_short |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_full |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_fullStr |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_full_unstemmed |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
title_sort |
Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study |
author |
Mendonça, José Carlos Garcia de |
author_facet |
Mendonça, José Carlos Garcia de Rossi, Rafael de Inouye, Celso Massaschi Bazan, Diego Rodrigo Paulillo Monteiro, João Carlos Castro Mendonça, Juliana Pedroso de |
author_role |
author |
author2 |
Rossi, Rafael de Inouye, Celso Massaschi Bazan, Diego Rodrigo Paulillo Monteiro, João Carlos Castro Mendonça, Juliana Pedroso de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Mendonça, José Carlos Garcia de Rossi, Rafael de Inouye, Celso Massaschi Bazan, Diego Rodrigo Paulillo Monteiro, João Carlos Castro Mendonça, Juliana Pedroso de |
dc.subject.por.fl_str_mv |
Materiais Biocompatíveis Transplante Ósseo Óleo de Rícino Coelhos Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
topic |
Materiais Biocompatíveis Transplante Ósseo Óleo de Rícino Coelhos Biocompatible Materials Bone Transplantation Castor Oil Rabbits |
description |
PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006 |
dc.date.accessioned.fl_str_mv |
2011-07-14T14:27:48Z |
dc.date.available.fl_str_mv |
2021-09-30T19:55:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufms.br/handle/123456789/141 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0102-86502006000500012 |
identifier_str_mv |
MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012. 10.1590/S0102-86502006000500012 |
url |
https://repositorio.ufms.br/handle/123456789/141 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Acta Cirurgica Brasileira |
publisher.none.fl_str_mv |
Acta Cirurgica Brasileira |
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reponame:Repositório Institucional da UFMS instname:Universidade Federal de Mato Grosso do Sul (UFMS) instacron:UFMS |
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Universidade Federal de Mato Grosso do Sul (UFMS) |
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UFMS |
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UFMS |
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Repositório Institucional da UFMS |
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Repositório Institucional da UFMS |
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