Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study

Detalhes bibliográficos
Autor(a) principal: Mendonça, José Carlos Garcia de
Data de Publicação: 2006
Outros Autores: Rossi, Rafael de, Inouye, Celso Massaschi, Bazan, Diego Rodrigo Paulillo, Monteiro, João Carlos Castro, Mendonça, Juliana Pedroso de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMS
Texto Completo: https://repositorio.ufms.br/handle/123456789/141
Resumo: PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.
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spelling 2011-07-14T14:27:48Z2021-09-30T19:55:52Z2006MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012.https://repositorio.ufms.br/handle/123456789/14110.1590/S0102-86502006000500012PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.OBJETIVO: Estudo morfológico comparativo do implante de poliuretana de mamona e enxerto ósseo autógeno em defeito ósseo padrão em osso zigomático de coelhos. MÉTODOS: Vinte e quatro coelhos Nova Zelândia, machos, adultos, foram distribuídos aleatoriamente em dois grupos de 12. Defeitos de 5mm de diâmetro, perenes, foram confeccionados em osso zigomático e preenchidos com discos pré-fabricados de poliuretana no grupo experimento ou osso autógeno extraído da tíbia no grupo controle. Os animais foram sacrificados após 30, 60 e 90 dias e as peças anatômicas foram avaliadas macro e microscopicamente. Foram utilizados os testes de Student, Fisher,qui-quadrado e McNemar para a análise estatística dos resultados. RESULTADOS: A poliuretana e o osso autógeno se adaptaram ao defeito sem necessidade de fixação. Houve formação de tecido conjuntivo fibroso envolvendo a poliuretana, sem reação inflamatória ou presença de células gigantes. Verificaram-se áreas acidófilas e basófilas nos poros do material implantado, sugestivas de núcleos celulares. No grupo controle, observou-se aos 90 dias o reparo ósseo de padrão lamelar clássico. CONCLUSÃO: A poliuretana de mamona foi biocompatível e não causou reação inflamatória deletéria. Pode ser uma alternativa para o preenchimento de defeitos ósseos.engActa Cirurgica BrasileiraMateriais BiocompatíveisTransplante ÓsseoÓleo de RícinoCoelhosBiocompatible MaterialsBone TransplantationCastor OilRabbitsMorphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative studyEstudo morfológico comparativo do enxerto ósseo autógeno e polímero de mamona em rebordo infra-orbitário de coelhosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMendonça, José Carlos Garcia deRossi, Rafael deInouye, Celso MassaschiBazan, Diego Rodrigo PaulilloMonteiro, João Carlos CastroMendonça, Juliana Pedroso deinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMSinstname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSTHUMBNAILMorphology of autogenous.pdf.jpgMorphology of autogenous.pdf.jpgGenerated Thumbnailimage/jpeg1675https://repositorio.ufms.br/bitstream/123456789/141/4/Morphology%20of%20autogenous.pdf.jpg8ddf5bde587e29d66d3b3d158def1ac2MD54ORIGINALMorphology of autogenous.pdfMorphology of autogenous.pdfapplication/pdf315618https://repositorio.ufms.br/bitstream/123456789/141/1/Morphology%20of%20autogenous.pdf02d84bc75eaef05e48aa2b0ba735a837MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufms.br/bitstream/123456789/141/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTMorphology of autogenous.pdf.txtMorphology of autogenous.pdf.txtExtracted texttext/plain26356https://repositorio.ufms.br/bitstream/123456789/141/3/Morphology%20of%20autogenous.pdf.txt84bff2e567aca52f774357203c537237MD53123456789/1412021-09-30 15:55:52.346oai:repositorio.ufms.br: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Repositório InstitucionalPUBhttps://repositorio.ufms.br/oai/requestri.prograd@ufms.bropendoar:21242021-09-30T19:55:52Repositório Institucional da UFMS - Universidade Federal de Mato Grosso do Sul (UFMS)false
dc.title.pt_BR.fl_str_mv Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
dc.title.alternative.pt_BR.fl_str_mv Estudo morfológico comparativo do enxerto ósseo autógeno e polímero de mamona em rebordo infra-orbitário de coelhos
title Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
spellingShingle Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
Mendonça, José Carlos Garcia de
Materiais Biocompatíveis
Transplante Ósseo
Óleo de Rícino
Coelhos
Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
title_short Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_full Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_fullStr Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_full_unstemmed Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
title_sort Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study
author Mendonça, José Carlos Garcia de
author_facet Mendonça, José Carlos Garcia de
Rossi, Rafael de
Inouye, Celso Massaschi
Bazan, Diego Rodrigo Paulillo
Monteiro, João Carlos Castro
Mendonça, Juliana Pedroso de
author_role author
author2 Rossi, Rafael de
Inouye, Celso Massaschi
Bazan, Diego Rodrigo Paulillo
Monteiro, João Carlos Castro
Mendonça, Juliana Pedroso de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mendonça, José Carlos Garcia de
Rossi, Rafael de
Inouye, Celso Massaschi
Bazan, Diego Rodrigo Paulillo
Monteiro, João Carlos Castro
Mendonça, Juliana Pedroso de
dc.subject.por.fl_str_mv Materiais Biocompatíveis
Transplante Ósseo
Óleo de Rícino
Coelhos
Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
topic Materiais Biocompatíveis
Transplante Ósseo
Óleo de Rícino
Coelhos
Biocompatible Materials
Bone Transplantation
Castor Oil
Rabbits
description PURPOSE: Morphological study comparing castor oil polyurethane and autogenous bone graft to repair bone defect in zygomatic bone of rabbits. METHODS: Twenty-four adult, male New Zealand rabbits were randomly distributed between two groups of twelve. Bone defects of 5mm in diameter were cut through the zygomatic bone and filled with polyurethane discs in the experimental group or autogenous bone harvested from the tibia in the control group. Animals were sacrificed after 30, 60 or 90 days, and the zygomatic bones were macro- and microscopically analyzed. Student's, Fisher's, chi-squared and McNemar's tests were used for statistical analysis. RESULTS: Both the castor oil polyurethane and the autograft adapted well to the defect, with no need for fixation. Fibrous connective tissue encapsulated the polyurethane, but no inflammation or giant cell reaction was observed. Acidophilic and basophilic areas were observed inside the micropores of the polyurethane, suggesting cell nuclei. After 90 days, bone repair with a lamellar pattern of organization was observed in the control group. CONCLUSION: The castor oil polyurethane was biocompatible and did not cause inflammation. It may be considered an alternative to fill bone defects.
publishDate 2006
dc.date.issued.fl_str_mv 2006
dc.date.accessioned.fl_str_mv 2011-07-14T14:27:48Z
dc.date.available.fl_str_mv 2021-09-30T19:55:52Z
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dc.identifier.citation.fl_str_mv MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012.
dc.identifier.uri.fl_str_mv https://repositorio.ufms.br/handle/123456789/141
dc.identifier.doi.none.fl_str_mv 10.1590/S0102-86502006000500012
identifier_str_mv MENDONCA, José Carlos Garcia de et al . Morphology of autogenous bone graft and castor oil polyurethane in the infraorbital rim of rabbits: a comparative study. Acta Cir. Bras., São Paulo, v. 21, n. 5, Oct. 2006 . Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502006000500012&lng=en&nrm=iso>. access on 14 July 2011. doi: 10.1590/S0102-86502006000500012.
10.1590/S0102-86502006000500012
url https://repositorio.ufms.br/handle/123456789/141
dc.language.iso.fl_str_mv eng
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dc.publisher.none.fl_str_mv Acta Cirurgica Brasileira
publisher.none.fl_str_mv Acta Cirurgica Brasileira
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMS
instname:Universidade Federal de Mato Grosso do Sul (UFMS)
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