Uric acid as a monitor of oxidative stress in a random skin flap in rats

Detalhes bibliográficos
Autor(a) principal: Freire,Sueli Teresinha
Data de Publicação: 2003
Outros Autores: Ferreira,Lydia Masako, Gomes,Heitor Carvalho, Percario,Sandro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502003000600009
Resumo: PURPOSE: To verify the possible role of uric acid as a monitor of oxidative stress in a random skin flap, in the rat. METHODS: This study utilized 21 adult male Wistar-EPM rats divided, at random, in three groups of seven animals, to evaluate the behavior of uric acid levels during oxidative stress zero, 5 and 15 minutes after elevation of the flap. According to the time schedule, skin samples were collected in order to allow determination of uric acid and malondialdehyde (MDA) levels. RESULTS: Uric acid levels in the skin samples did not change with time, but the values in normal skin were higher since the beginning. Malondialdehyde (MDA) levels in the skin samples remained stable throughout. CONCLUSION: Uric acid levels in the flap skin were lower than those in the normal skin, denoting local oxidative stress.
id SBDPC-1_77b007b6d031014ef85535af74cbae4a
oai_identifier_str oai:scielo:S0102-86502003000600009
network_acronym_str SBDPC-1
network_name_str Acta Cirúrgica Brasileira (Online)
repository_id_str
spelling Uric acid as a monitor of oxidative stress in a random skin flap in ratsSurgical flapsLipid peroxidationUric acidRatsPURPOSE: To verify the possible role of uric acid as a monitor of oxidative stress in a random skin flap, in the rat. METHODS: This study utilized 21 adult male Wistar-EPM rats divided, at random, in three groups of seven animals, to evaluate the behavior of uric acid levels during oxidative stress zero, 5 and 15 minutes after elevation of the flap. According to the time schedule, skin samples were collected in order to allow determination of uric acid and malondialdehyde (MDA) levels. RESULTS: Uric acid levels in the skin samples did not change with time, but the values in normal skin were higher since the beginning. Malondialdehyde (MDA) levels in the skin samples remained stable throughout. CONCLUSION: Uric acid levels in the flap skin were lower than those in the normal skin, denoting local oxidative stress.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2003-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502003000600009Acta Cirúrgica Brasileira v.18 n.6 2003reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502003000600009info:eu-repo/semantics/openAccessFreire,Sueli TeresinhaFerreira,Lydia MasakoGomes,Heitor CarvalhoPercario,Sandroeng2007-04-19T00:00:00Zoai:scielo:S0102-86502003000600009Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2007-04-19T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Uric acid as a monitor of oxidative stress in a random skin flap in rats
title Uric acid as a monitor of oxidative stress in a random skin flap in rats
spellingShingle Uric acid as a monitor of oxidative stress in a random skin flap in rats
Freire,Sueli Teresinha
Surgical flaps
Lipid peroxidation
Uric acid
Rats
title_short Uric acid as a monitor of oxidative stress in a random skin flap in rats
title_full Uric acid as a monitor of oxidative stress in a random skin flap in rats
title_fullStr Uric acid as a monitor of oxidative stress in a random skin flap in rats
title_full_unstemmed Uric acid as a monitor of oxidative stress in a random skin flap in rats
title_sort Uric acid as a monitor of oxidative stress in a random skin flap in rats
author Freire,Sueli Teresinha
author_facet Freire,Sueli Teresinha
Ferreira,Lydia Masako
Gomes,Heitor Carvalho
Percario,Sandro
author_role author
author2 Ferreira,Lydia Masako
Gomes,Heitor Carvalho
Percario,Sandro
author2_role author
author
author
dc.contributor.author.fl_str_mv Freire,Sueli Teresinha
Ferreira,Lydia Masako
Gomes,Heitor Carvalho
Percario,Sandro
dc.subject.por.fl_str_mv Surgical flaps
Lipid peroxidation
Uric acid
Rats
topic Surgical flaps
Lipid peroxidation
Uric acid
Rats
description PURPOSE: To verify the possible role of uric acid as a monitor of oxidative stress in a random skin flap, in the rat. METHODS: This study utilized 21 adult male Wistar-EPM rats divided, at random, in three groups of seven animals, to evaluate the behavior of uric acid levels during oxidative stress zero, 5 and 15 minutes after elevation of the flap. According to the time schedule, skin samples were collected in order to allow determination of uric acid and malondialdehyde (MDA) levels. RESULTS: Uric acid levels in the skin samples did not change with time, but the values in normal skin were higher since the beginning. Malondialdehyde (MDA) levels in the skin samples remained stable throughout. CONCLUSION: Uric acid levels in the flap skin were lower than those in the normal skin, denoting local oxidative stress.
publishDate 2003
dc.date.none.fl_str_mv 2003-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502003000600009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502003000600009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502003000600009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.18 n.6 2003
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
_version_ 1752126436888543232

Registros relacionados