Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201 |
Resumo: | ABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen. |
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Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in ratsElectric StimulationCollagenAchilles TendonWound HealingRatsABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201Acta Cirúrgica Brasileira v.36 n.1 2021reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/acb360103info:eu-repo/semantics/openAccessCasagrande,Sharbo MartinsBiondo-Simões,Maria de Lourdes PessoleIoshii,SergioRobes,Rogério RibeiroBiondo-Simões,RachelBoeno,Bruno Russiano de Oliveiraeng2021-01-29T00:00:00Zoai:scielo:S0102-86502021000100201Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2021-01-29T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
title |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
spellingShingle |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats Casagrande,Sharbo Martins Electric Stimulation Collagen Achilles Tendon Wound Healing Rats |
title_short |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
title_full |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
title_fullStr |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
title_full_unstemmed |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
title_sort |
Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats |
author |
Casagrande,Sharbo Martins |
author_facet |
Casagrande,Sharbo Martins Biondo-Simões,Maria de Lourdes Pessole Ioshii,Sergio Robes,Rogério Ribeiro Biondo-Simões,Rachel Boeno,Bruno Russiano de Oliveira |
author_role |
author |
author2 |
Biondo-Simões,Maria de Lourdes Pessole Ioshii,Sergio Robes,Rogério Ribeiro Biondo-Simões,Rachel Boeno,Bruno Russiano de Oliveira |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Casagrande,Sharbo Martins Biondo-Simões,Maria de Lourdes Pessole Ioshii,Sergio Robes,Rogério Ribeiro Biondo-Simões,Rachel Boeno,Bruno Russiano de Oliveira |
dc.subject.por.fl_str_mv |
Electric Stimulation Collagen Achilles Tendon Wound Healing Rats |
topic |
Electric Stimulation Collagen Achilles Tendon Wound Healing Rats |
description |
ABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/acb360103 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.36 n.1 2021 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126445911539712 |