Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats

Detalhes bibliográficos
Autor(a) principal: Casagrande,Sharbo Martins
Data de Publicação: 2021
Outros Autores: Biondo-Simões,Maria de Lourdes Pessole, Ioshii,Sergio, Robes,Rogério Ribeiro, Biondo-Simões,Rachel, Boeno,Bruno Russiano de Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201
Resumo: ABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen.
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spelling Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in ratsElectric StimulationCollagenAchilles TendonWound HealingRatsABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201Acta Cirúrgica Brasileira v.36 n.1 2021reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/acb360103info:eu-repo/semantics/openAccessCasagrande,Sharbo MartinsBiondo-Simões,Maria de Lourdes PessoleIoshii,SergioRobes,Rogério RibeiroBiondo-Simões,RachelBoeno,Bruno Russiano de Oliveiraeng2021-01-29T00:00:00Zoai:scielo:S0102-86502021000100201Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2021-01-29T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
title Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
spellingShingle Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
Casagrande,Sharbo Martins
Electric Stimulation
Collagen
Achilles Tendon
Wound Healing
Rats
title_short Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
title_full Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
title_fullStr Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
title_full_unstemmed Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
title_sort Histological evaluation of the effect of low-frequency electric stimulation on healing Achilles tendons in rats
author Casagrande,Sharbo Martins
author_facet Casagrande,Sharbo Martins
Biondo-Simões,Maria de Lourdes Pessole
Ioshii,Sergio
Robes,Rogério Ribeiro
Biondo-Simões,Rachel
Boeno,Bruno Russiano de Oliveira
author_role author
author2 Biondo-Simões,Maria de Lourdes Pessole
Ioshii,Sergio
Robes,Rogério Ribeiro
Biondo-Simões,Rachel
Boeno,Bruno Russiano de Oliveira
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Casagrande,Sharbo Martins
Biondo-Simões,Maria de Lourdes Pessole
Ioshii,Sergio
Robes,Rogério Ribeiro
Biondo-Simões,Rachel
Boeno,Bruno Russiano de Oliveira
dc.subject.por.fl_str_mv Electric Stimulation
Collagen
Achilles Tendon
Wound Healing
Rats
topic Electric Stimulation
Collagen
Achilles Tendon
Wound Healing
Rats
description ABSTRACT Purpose: Histologically evaluate the effects of low frequency electrical stimulation in the treatment of Achilles tendon injuries in rats. Methods: Thirty-four rats underwent Achilles tendon tenotomy and tenorrhaphy. They were randomly allocated in two groups. Half of the sample constituted the experiment group, whose lesions were stimulated with 2 Hz, nonpolarized current and 1 mA, for 14 days. The other animals formed the control group. They were evaluated at 2, 4 and 6 weeks. The histological study was carried out, the collagen density and the wound maturity index were measured. Results: The healing score was higher in the group stimulated at the 6th week (p = 0.018). The density collagen 1 was higher in the group treated at the three times (p = 0.004) and that collagen 3 was higher in the group treated at 6 weeks (p = 0.004). Together, collagen 1 and 3 were higher in the group stimulated at 4 and 6 weeks (p = 0.009, p = 0.004). The maturity index was higher in this group at the three moments (p = 0.017 p = 0.004 and p = 0.009). Conclusion: Low frequency electric stimulation improved healing and increased the quantity of collagen.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000100201
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/acb360103
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.36 n.1 2021
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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