Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000100024 |
Resumo: | PURPOSE: To evaluate the effects of acute administration of Sedum dendroideum on the gastric histopathology of rats after the administration of indomethacin.METHODS: Twenty four Wistar rats were randomized into three groups, submitted to feeding privation for 24 hours prior to the oral administration of 50 mg/Kg of indomethacin and during the experimental period of six hours. The control group (C) was giving distilled water, the extract group (E) was treated with the extract of Sedum dendroideum and the group Omeoprazole (O) received 20 mg/Kg of omeoprazole. All the treatments were carried out thirty minutes prior to the administration of indomethacin. After six hour, the stomach of the animals was extirpated for histopathological analysis, which took into account the presence of erosive gastritis, hyperemia and sub mucosa edema.RESULTS: In group C, eight out of eight animals presented that type of lesion, in group E, this number was the same and in group O, three out of the eight rats presented erosive gastritis.CONCLUSION: |
id |
SBDPC-1_9bb61be31fd41d337c65b94c8afca298 |
---|---|
oai_identifier_str |
oai:scielo:S0102-86502014000100024 |
network_acronym_str |
SBDPC-1 |
network_name_str |
Acta Cirúrgica Brasileira (Online) |
repository_id_str |
|
spelling |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in ratsPhytotherapyHistologyGastritisIndomethacinRatsPURPOSE: To evaluate the effects of acute administration of Sedum dendroideum on the gastric histopathology of rats after the administration of indomethacin.METHODS: Twenty four Wistar rats were randomized into three groups, submitted to feeding privation for 24 hours prior to the oral administration of 50 mg/Kg of indomethacin and during the experimental period of six hours. The control group (C) was giving distilled water, the extract group (E) was treated with the extract of Sedum dendroideum and the group Omeoprazole (O) received 20 mg/Kg of omeoprazole. All the treatments were carried out thirty minutes prior to the administration of indomethacin. After six hour, the stomach of the animals was extirpated for histopathological analysis, which took into account the presence of erosive gastritis, hyperemia and sub mucosa edema.RESULTS: In group C, eight out of eight animals presented that type of lesion, in group E, this number was the same and in group O, three out of the eight rats presented erosive gastritis.CONCLUSION:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000100024Acta Cirúrgica Brasileira v.29 n.1 2014reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502014000100004info:eu-repo/semantics/openAccessBaracho,Nilo César do ValeRibeiro,Rafaela VaziPereira,Renato MaduroIrulegui,Roseane de Souza Cândidoeng2015-10-08T00:00:00Zoai:scielo:S0102-86502014000100024Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2015-10-08T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
title |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
spellingShingle |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats Baracho,Nilo César do Vale Phytotherapy Histology Gastritis Indomethacin Rats |
title_short |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
title_full |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
title_fullStr |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
title_full_unstemmed |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
title_sort |
Effects of the administration of aqueous extract of deSedum dendroideum on the histopathology of erosive induced gastritis by means of indomethacin in rats |
author |
Baracho,Nilo César do Vale |
author_facet |
Baracho,Nilo César do Vale Ribeiro,Rafaela Vazi Pereira,Renato Maduro Irulegui,Roseane de Souza Cândido |
author_role |
author |
author2 |
Ribeiro,Rafaela Vazi Pereira,Renato Maduro Irulegui,Roseane de Souza Cândido |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Baracho,Nilo César do Vale Ribeiro,Rafaela Vazi Pereira,Renato Maduro Irulegui,Roseane de Souza Cândido |
dc.subject.por.fl_str_mv |
Phytotherapy Histology Gastritis Indomethacin Rats |
topic |
Phytotherapy Histology Gastritis Indomethacin Rats |
description |
PURPOSE: To evaluate the effects of acute administration of Sedum dendroideum on the gastric histopathology of rats after the administration of indomethacin.METHODS: Twenty four Wistar rats were randomized into three groups, submitted to feeding privation for 24 hours prior to the oral administration of 50 mg/Kg of indomethacin and during the experimental period of six hours. The control group (C) was giving distilled water, the extract group (E) was treated with the extract of Sedum dendroideum and the group Omeoprazole (O) received 20 mg/Kg of omeoprazole. All the treatments were carried out thirty minutes prior to the administration of indomethacin. After six hour, the stomach of the animals was extirpated for histopathological analysis, which took into account the presence of erosive gastritis, hyperemia and sub mucosa edema.RESULTS: In group C, eight out of eight animals presented that type of lesion, in group E, this number was the same and in group O, three out of the eight rats presented erosive gastritis.CONCLUSION: |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000100024 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502014000100024 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-86502014000100004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.29 n.1 2014 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126442204823552 |