Porcine peritoneum as source of biocompatible collagen in mice

Detalhes bibliográficos
Autor(a) principal: Jardelino,Cristina
Data de Publicação: 2010
Outros Autores: Takamori,Esther Rieko, Hermida,Luiz Felipe, Lenharo,Ariel, Castro-Silva,Igor Iuco, Granjeiro,Jose Mauro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000400006
Resumo: PURPOSE: To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum. METHODS: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections. RESULTS: After one week, mononuclear cells were observed inside the membrane. After three weeks, the material was almost completely absorbed. After nine weeks, there was no presence of material and there were signs of tissue remodeling. There was neither a foreign body reaction nor signs of tissue necrosis. CONCLUSION: The collagen membrane derived from porcine peritoneum is biocompatible and bioabsorbable when implanted in the subcutaneous tissue of mice.
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spelling Porcine peritoneum as source of biocompatible collagen in miceMaterials TestingBiocompatible MaterialsSubcutaneous TissuePeritoneumMicePURPOSE: To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum. METHODS: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections. RESULTS: After one week, mononuclear cells were observed inside the membrane. After three weeks, the material was almost completely absorbed. After nine weeks, there was no presence of material and there were signs of tissue remodeling. There was neither a foreign body reaction nor signs of tissue necrosis. CONCLUSION: The collagen membrane derived from porcine peritoneum is biocompatible and bioabsorbable when implanted in the subcutaneous tissue of mice.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2010-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000400006Acta Cirúrgica Brasileira v.25 n.4 2010reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502010000400006info:eu-repo/semantics/openAccessJardelino,CristinaTakamori,Esther RiekoHermida,Luiz FelipeLenharo,ArielCastro-Silva,Igor IucoGranjeiro,Jose Mauroeng2010-07-26T00:00:00Zoai:scielo:S0102-86502010000400006Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2010-07-26T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Porcine peritoneum as source of biocompatible collagen in mice
title Porcine peritoneum as source of biocompatible collagen in mice
spellingShingle Porcine peritoneum as source of biocompatible collagen in mice
Jardelino,Cristina
Materials Testing
Biocompatible Materials
Subcutaneous Tissue
Peritoneum
Mice
title_short Porcine peritoneum as source of biocompatible collagen in mice
title_full Porcine peritoneum as source of biocompatible collagen in mice
title_fullStr Porcine peritoneum as source of biocompatible collagen in mice
title_full_unstemmed Porcine peritoneum as source of biocompatible collagen in mice
title_sort Porcine peritoneum as source of biocompatible collagen in mice
author Jardelino,Cristina
author_facet Jardelino,Cristina
Takamori,Esther Rieko
Hermida,Luiz Felipe
Lenharo,Ariel
Castro-Silva,Igor Iuco
Granjeiro,Jose Mauro
author_role author
author2 Takamori,Esther Rieko
Hermida,Luiz Felipe
Lenharo,Ariel
Castro-Silva,Igor Iuco
Granjeiro,Jose Mauro
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Jardelino,Cristina
Takamori,Esther Rieko
Hermida,Luiz Felipe
Lenharo,Ariel
Castro-Silva,Igor Iuco
Granjeiro,Jose Mauro
dc.subject.por.fl_str_mv Materials Testing
Biocompatible Materials
Subcutaneous Tissue
Peritoneum
Mice
topic Materials Testing
Biocompatible Materials
Subcutaneous Tissue
Peritoneum
Mice
description PURPOSE: To investigate the biocompatibility and biodegradability of a membrane made from porcine peritoneum. METHODS: The membrane (5x5 mm) was inserted in the subcutaneous tissue on the back of 15 mice, which were killed after 1, 3 and 9 weeks (ISO 10993-6). The cellular components of the inflammatory response and degradation of the membrane were analyzed in hematoxylin-eosin-stained histological sections. RESULTS: After one week, mononuclear cells were observed inside the membrane. After three weeks, the material was almost completely absorbed. After nine weeks, there was no presence of material and there were signs of tissue remodeling. There was neither a foreign body reaction nor signs of tissue necrosis. CONCLUSION: The collagen membrane derived from porcine peritoneum is biocompatible and bioabsorbable when implanted in the subcutaneous tissue of mice.
publishDate 2010
dc.date.none.fl_str_mv 2010-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000400006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502010000400006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502010000400006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.25 n.4 2010
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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