A system for treatment of diabetic foot ulcers using led irradiation and natural latex

• Autor(a) principal: Nunes,Gustavo Adolfo Marcelino de Almeida
• Data de Publicação: 2016
• Outros Autores: Reis,Maria do Carmo dos, Rosa,Mário Fabrício Fleury, Peixoto,Luciana Roberta Tenório, Rocha,Adson Ferreira da, Rosa,Suélia de Siqueira Rodrigues Fleury
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Research on Biomedical Engineering (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2446-47402016000100003
• topic: Diabetes; Tissue formation; Inducer system; Diabetic foot; Latex; LED

Abstract Introduction: We developed and tested a new system for inducing the healing of diabetic foot ulcers. The system relies on the regenerative properties of its two components: an insole with a sheet of natural latex and a device that contains a matrix of light emitting diodes with wavelength of 635 nm. Methods The electronic and latex based devices were developed, and a four weeks test was performed in one control group (CG) of five ulcers and one experimental group (EG) of eight ulcers. The CG was treated with a standard approach, based on a silver-releasing foam dressing, and the EG was treated with the system under test. For each ulcer, an index for quantifying the percentage ulcer recovery, named CRU(%), has been calculated; a CRU(%) = 0% means no healing, and a CRU(%) = 100% means total healing. Results There were statistically significant increases of CRU(%) of 51.8% (p = 0.022), for the CG, and of 78.4% (p < 0.001), for the EG. The increase in the EG was higher than the increase in the CG, and the difference was statistically significant (p < 0.001). The results showed that the proposed method had, for these particular sets of ulcers, faster healing rates, than for the standard method. Conclusion The results hint that the proposed method seems promising as a future treatment method. However, the technique must undergo further testing before it can be considered for extensive clinical applications.