Galvanic vestibular stimulator for fMRI studies

Detalhes bibliográficos
Autor(a) principal: Della-Justina,Hellen Mathei
Data de Publicação: 2014
Outros Autores: Manczak,Tiago, Winkler,Anderson Marcelo, Araújo,Dráulio Barros de, Souza,Mauren Abreu de, Amaro Junior,Edson, Gamba,Humberto Remigio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Engenharia Biomédica (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-31512014000100010
Resumo: INTRODUCTION: Areas of the brain that are associated with the vestibular system can be activated using galvanic vestibular stimulation. These areas can be studied through a combination of galvanic vestibular stimulation with functional magnetic resonance imaging (fMRI). In order to provide an appropriate sequence of galvanic stimulation synchronous with the MRI pulse sequence, a specific electronic device that was built and assessed is presented. METHODS: The electronic project of the GVS is divided in analog and digital circuits. The analog circuits are mounted in an aluminum case, supplied by sealed batteries, and goes inside the MRI room near to the feet of the subject. The digital circuits are placed in the MRI control room. Those circuits communicate through each other by an optical fiber. Tests to verify the GVS-MRI compatibility were conducted. Silicone (in-house) and Ag/AgCl (commercial) electrodes were evaluated for maximum balance and minimal pain sensations. fMRI experiments were conducted in eight human volunteers. RESULTS: GVS-MRI compatibility experiments demonstrate that the GVS did not interfere with the MRI scanner functionality and vice versa. The circular silicone electrode was considered the most suitable to apply the galvanic vestibular stimulation. The 1 Hz stimulation sinusoid frequency produced the biggest balance and the less pain sensations when compared to 2 Hz. The GVS was capable of eliciting activation in the precentral and postcentral gyri, in the central sulcus, in the supplementary motor area, in the middle and inferior frontal gyri, in the inferior parietal lobule, in the insula, in the superior temporal gyrus, in the middle cingulate cortex, and in the cerebellum. CONCLUSION: This study shows the development and description of a neurovestibular stimulator that can be safely used inside the MRI scanner room without interfering on its operation and vice versa. The developed GVS could successfully activate the major areas involved with multimodal functions of the vestibular system, demonstrating its validity as a stimulator for neurovestibular research. To the best of our knowledge, this is the first work that shows the development and the construction of a galvanic vestibular stimulator that could be safely used inside the MRI room.
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spelling Galvanic vestibular stimulator for fMRI studiesDevicesfMRIVestibular apparatusElectrical stimulationINTRODUCTION: Areas of the brain that are associated with the vestibular system can be activated using galvanic vestibular stimulation. These areas can be studied through a combination of galvanic vestibular stimulation with functional magnetic resonance imaging (fMRI). In order to provide an appropriate sequence of galvanic stimulation synchronous with the MRI pulse sequence, a specific electronic device that was built and assessed is presented. METHODS: The electronic project of the GVS is divided in analog and digital circuits. The analog circuits are mounted in an aluminum case, supplied by sealed batteries, and goes inside the MRI room near to the feet of the subject. The digital circuits are placed in the MRI control room. Those circuits communicate through each other by an optical fiber. Tests to verify the GVS-MRI compatibility were conducted. Silicone (in-house) and Ag/AgCl (commercial) electrodes were evaluated for maximum balance and minimal pain sensations. fMRI experiments were conducted in eight human volunteers. RESULTS: GVS-MRI compatibility experiments demonstrate that the GVS did not interfere with the MRI scanner functionality and vice versa. The circular silicone electrode was considered the most suitable to apply the galvanic vestibular stimulation. The 1 Hz stimulation sinusoid frequency produced the biggest balance and the less pain sensations when compared to 2 Hz. The GVS was capable of eliciting activation in the precentral and postcentral gyri, in the central sulcus, in the supplementary motor area, in the middle and inferior frontal gyri, in the inferior parietal lobule, in the insula, in the superior temporal gyrus, in the middle cingulate cortex, and in the cerebellum. CONCLUSION: This study shows the development and description of a neurovestibular stimulator that can be safely used inside the MRI scanner room without interfering on its operation and vice versa. The developed GVS could successfully activate the major areas involved with multimodal functions of the vestibular system, demonstrating its validity as a stimulator for neurovestibular research. To the best of our knowledge, this is the first work that shows the development and the construction of a galvanic vestibular stimulator that could be safely used inside the MRI room.SBEB - Sociedade Brasileira de Engenharia Biomédica2014-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-31512014000100010Revista Brasileira de Engenharia Biomédica v.30 n.1 2014reponame:Revista Brasileira de Engenharia Biomédica (Online)instname:Sociedade Brasileira de Engenharia Biomédica (SBEB)instacron:SBEB10.4322/rbeb.2013.046info:eu-repo/semantics/openAccessDella-Justina,Hellen MatheiManczak,TiagoWinkler,Anderson MarceloAraújo,Dráulio Barros deSouza,Mauren Abreu deAmaro Junior,EdsonGamba,Humberto Remigioeng2014-04-23T00:00:00Zoai:scielo:S1517-31512014000100010Revistahttp://www.scielo.br/rbebONGhttps://old.scielo.br/oai/scielo-oai.php||rbeb@rbeb.org.br1984-77421517-3151opendoar:2014-04-23T00:00Revista Brasileira de Engenharia Biomédica (Online) - Sociedade Brasileira de Engenharia Biomédica (SBEB)false
dc.title.none.fl_str_mv Galvanic vestibular stimulator for fMRI studies
title Galvanic vestibular stimulator for fMRI studies
spellingShingle Galvanic vestibular stimulator for fMRI studies
Della-Justina,Hellen Mathei
Devices
fMRI
Vestibular apparatus
Electrical stimulation
title_short Galvanic vestibular stimulator for fMRI studies
title_full Galvanic vestibular stimulator for fMRI studies
title_fullStr Galvanic vestibular stimulator for fMRI studies
title_full_unstemmed Galvanic vestibular stimulator for fMRI studies
title_sort Galvanic vestibular stimulator for fMRI studies
author Della-Justina,Hellen Mathei
author_facet Della-Justina,Hellen Mathei
Manczak,Tiago
Winkler,Anderson Marcelo
Araújo,Dráulio Barros de
Souza,Mauren Abreu de
Amaro Junior,Edson
Gamba,Humberto Remigio
author_role author
author2 Manczak,Tiago
Winkler,Anderson Marcelo
Araújo,Dráulio Barros de
Souza,Mauren Abreu de
Amaro Junior,Edson
Gamba,Humberto Remigio
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Della-Justina,Hellen Mathei
Manczak,Tiago
Winkler,Anderson Marcelo
Araújo,Dráulio Barros de
Souza,Mauren Abreu de
Amaro Junior,Edson
Gamba,Humberto Remigio
dc.subject.por.fl_str_mv Devices
fMRI
Vestibular apparatus
Electrical stimulation
topic Devices
fMRI
Vestibular apparatus
Electrical stimulation
description INTRODUCTION: Areas of the brain that are associated with the vestibular system can be activated using galvanic vestibular stimulation. These areas can be studied through a combination of galvanic vestibular stimulation with functional magnetic resonance imaging (fMRI). In order to provide an appropriate sequence of galvanic stimulation synchronous with the MRI pulse sequence, a specific electronic device that was built and assessed is presented. METHODS: The electronic project of the GVS is divided in analog and digital circuits. The analog circuits are mounted in an aluminum case, supplied by sealed batteries, and goes inside the MRI room near to the feet of the subject. The digital circuits are placed in the MRI control room. Those circuits communicate through each other by an optical fiber. Tests to verify the GVS-MRI compatibility were conducted. Silicone (in-house) and Ag/AgCl (commercial) electrodes were evaluated for maximum balance and minimal pain sensations. fMRI experiments were conducted in eight human volunteers. RESULTS: GVS-MRI compatibility experiments demonstrate that the GVS did not interfere with the MRI scanner functionality and vice versa. The circular silicone electrode was considered the most suitable to apply the galvanic vestibular stimulation. The 1 Hz stimulation sinusoid frequency produced the biggest balance and the less pain sensations when compared to 2 Hz. The GVS was capable of eliciting activation in the precentral and postcentral gyri, in the central sulcus, in the supplementary motor area, in the middle and inferior frontal gyri, in the inferior parietal lobule, in the insula, in the superior temporal gyrus, in the middle cingulate cortex, and in the cerebellum. CONCLUSION: This study shows the development and description of a neurovestibular stimulator that can be safely used inside the MRI scanner room without interfering on its operation and vice versa. The developed GVS could successfully activate the major areas involved with multimodal functions of the vestibular system, demonstrating its validity as a stimulator for neurovestibular research. To the best of our knowledge, this is the first work that shows the development and the construction of a galvanic vestibular stimulator that could be safely used inside the MRI room.
publishDate 2014
dc.date.none.fl_str_mv 2014-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-31512014000100010
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.4322/rbeb.2013.046
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv SBEB - Sociedade Brasileira de Engenharia Biomédica
publisher.none.fl_str_mv SBEB - Sociedade Brasileira de Engenharia Biomédica
dc.source.none.fl_str_mv Revista Brasileira de Engenharia Biomédica v.30 n.1 2014
reponame:Revista Brasileira de Engenharia Biomédica (Online)
instname:Sociedade Brasileira de Engenharia Biomédica (SBEB)
instacron:SBEB
instname_str Sociedade Brasileira de Engenharia Biomédica (SBEB)
instacron_str SBEB
institution SBEB
reponame_str Revista Brasileira de Engenharia Biomédica (Online)
collection Revista Brasileira de Engenharia Biomédica (Online)
repository.name.fl_str_mv Revista Brasileira de Engenharia Biomédica (Online) - Sociedade Brasileira de Engenharia Biomédica (SBEB)
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