Post-transplantation osteoporosis

Detalhes bibliográficos
Autor(a) principal: Kulak,Carolina A. Moreira
Data de Publicação: 2010
Outros Autores: Borba,Victória Z. Cochenski, Kulak Júnior,Jaime, Campos,Denise Jonhsson, Shane,Elizabeth
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302010000200009
Resumo: Transplantation is an established therapy for many hematologic disorders as well as for end-stage diseases of the kidney, lung, liver, heart among others. Osteoporosis and a high incidence of fragility fractures have emerged as a complication of organ transplantation. Many factors contribute to the pathogenesis of osteoporosis following organ transplantation. In addition, most patients have some form of bone disease prior to transplantation, which is usually related to adverse effects of end-stage organ failure on the skeleton. This chapter reviews the mechanisms of bone loss that occur both in the early and late post-transplant periods including the contribution of immunosuppressive agents as well as the specific features of bone loss after kidney, lung, liver, cardiac and bone marrow transplantation. Prevention and treatment for osteoporosis in the transplant recipient will also be addressed.
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spelling Post-transplantation osteoporosisSecondary osteoporosistransplantationimmunosuppressive agentsbone lossTransplantation is an established therapy for many hematologic disorders as well as for end-stage diseases of the kidney, lung, liver, heart among others. Osteoporosis and a high incidence of fragility fractures have emerged as a complication of organ transplantation. Many factors contribute to the pathogenesis of osteoporosis following organ transplantation. In addition, most patients have some form of bone disease prior to transplantation, which is usually related to adverse effects of end-stage organ failure on the skeleton. This chapter reviews the mechanisms of bone loss that occur both in the early and late post-transplant periods including the contribution of immunosuppressive agents as well as the specific features of bone loss after kidney, lung, liver, cardiac and bone marrow transplantation. Prevention and treatment for osteoporosis in the transplant recipient will also be addressed.Sociedade Brasileira de Endocrinologia e Metabologia2010-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302010000200009Arquivos Brasileiros de Endocrinologia & Metabologia v.54 n.2 2010reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)instacron:SBEM10.1590/S0004-27302010000200009info:eu-repo/semantics/openAccessKulak,Carolina A. MoreiraBorba,Victória Z. CochenskiKulak Júnior,JaimeCampos,Denise JonhssonShane,Elizabetheng2010-05-21T00:00:00Zoai:scielo:S0004-27302010000200009Revistahttps://www.aem-sbem.com/ONGhttps://old.scielo.br/oai/scielo-oai.php||abem-editoria@endocrino.org.br1677-94870004-2730opendoar:2010-05-21T00:00Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)false
dc.title.none.fl_str_mv Post-transplantation osteoporosis
title Post-transplantation osteoporosis
spellingShingle Post-transplantation osteoporosis
Kulak,Carolina A. Moreira
Secondary osteoporosis
transplantation
immunosuppressive agents
bone loss
title_short Post-transplantation osteoporosis
title_full Post-transplantation osteoporosis
title_fullStr Post-transplantation osteoporosis
title_full_unstemmed Post-transplantation osteoporosis
title_sort Post-transplantation osteoporosis
author Kulak,Carolina A. Moreira
author_facet Kulak,Carolina A. Moreira
Borba,Victória Z. Cochenski
Kulak Júnior,Jaime
Campos,Denise Jonhsson
Shane,Elizabeth
author_role author
author2 Borba,Victória Z. Cochenski
Kulak Júnior,Jaime
Campos,Denise Jonhsson
Shane,Elizabeth
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Kulak,Carolina A. Moreira
Borba,Victória Z. Cochenski
Kulak Júnior,Jaime
Campos,Denise Jonhsson
Shane,Elizabeth
dc.subject.por.fl_str_mv Secondary osteoporosis
transplantation
immunosuppressive agents
bone loss
topic Secondary osteoporosis
transplantation
immunosuppressive agents
bone loss
description Transplantation is an established therapy for many hematologic disorders as well as for end-stage diseases of the kidney, lung, liver, heart among others. Osteoporosis and a high incidence of fragility fractures have emerged as a complication of organ transplantation. Many factors contribute to the pathogenesis of osteoporosis following organ transplantation. In addition, most patients have some form of bone disease prior to transplantation, which is usually related to adverse effects of end-stage organ failure on the skeleton. This chapter reviews the mechanisms of bone loss that occur both in the early and late post-transplant periods including the contribution of immunosuppressive agents as well as the specific features of bone loss after kidney, lung, liver, cardiac and bone marrow transplantation. Prevention and treatment for osteoporosis in the transplant recipient will also be addressed.
publishDate 2010
dc.date.none.fl_str_mv 2010-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302010000200009
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0004-27302010000200009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia v.54 n.2 2010
reponame:Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
instname:Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
instname_str Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron_str SBEM
institution SBEM
reponame_str Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
collection Arquivos Brasileiros de Endocrinologia & Metabologia (Online)
repository.name.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia (Online) - Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
repository.mail.fl_str_mv ||abem-editoria@endocrino.org.br
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