Antimicrobial properties of the mushroom Agaricus blazei – integrative review

Detalhes bibliográficos
Autor(a) principal: Lima,Cristiane U.J.O.
Data de Publicação: 2016
Outros Autores: Gris,Eliana F., Karnikowski,Margô G.O.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2016000600780
Resumo: ABSTRACT Infectious diseases associated with antimicrobial resistance are considered to represent an important public health problem. In this regard, the mushroom Agaricus blazei Murrill contains several bioactive substances that promote significant functional properties, among them, antimicrobial activity, which has attracted the interest of the scientific community. Thus, the aim of this study was to determine whether evidence of the antimicrobial action of A. blazei has been reported in the literature. In this integrative review, manuscripts held in research databases available online were examined with a view to answering the question “Does the mushroom A. blazei exert antimicrobial activity against Gram-negative and/or Gram-positive bacteria?” Only eight scientific articles that have addressed the antimicrobial properties of A. blazei, in vitro and in vivo, were found, all characterized as pre-clinical, i.e., with level VII evidence. Most authors have found that the A. blazei extract promotes an antimicrobial effect against peritonitis, as well as deadly oral infections, especially those caused by Gram-positive bacteria. However, the scientific data currently available are not sufficient to verify the antimicrobial aspect of the mushroom A. blazei and thus further investigation is required.
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spelling Antimicrobial properties of the mushroom Agaricus blazei – integrative reviewAgaricus blazeiAntibioticAntimicrobialAntimicrobial agentsInfectionABSTRACT Infectious diseases associated with antimicrobial resistance are considered to represent an important public health problem. In this regard, the mushroom Agaricus blazei Murrill contains several bioactive substances that promote significant functional properties, among them, antimicrobial activity, which has attracted the interest of the scientific community. Thus, the aim of this study was to determine whether evidence of the antimicrobial action of A. blazei has been reported in the literature. In this integrative review, manuscripts held in research databases available online were examined with a view to answering the question “Does the mushroom A. blazei exert antimicrobial activity against Gram-negative and/or Gram-positive bacteria?” Only eight scientific articles that have addressed the antimicrobial properties of A. blazei, in vitro and in vivo, were found, all characterized as pre-clinical, i.e., with level VII evidence. Most authors have found that the A. blazei extract promotes an antimicrobial effect against peritonitis, as well as deadly oral infections, especially those caused by Gram-positive bacteria. However, the scientific data currently available are not sufficient to verify the antimicrobial aspect of the mushroom A. blazei and thus further investigation is required.Sociedade Brasileira de Farmacognosia2016-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2016000600780Revista Brasileira de Farmacognosia v.26 n.6 2016reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2016.05.013info:eu-repo/semantics/openAccessLima,Cristiane U.J.O.Gris,Eliana F.Karnikowski,Margô G.O.eng2016-12-05T00:00:00Zoai:scielo:S0102-695X2016000600780Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2016-12-05T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Antimicrobial properties of the mushroom Agaricus blazei – integrative review
title Antimicrobial properties of the mushroom Agaricus blazei – integrative review
spellingShingle Antimicrobial properties of the mushroom Agaricus blazei – integrative review
Lima,Cristiane U.J.O.
Agaricus blazei
Antibiotic
Antimicrobial
Antimicrobial agents
Infection
title_short Antimicrobial properties of the mushroom Agaricus blazei – integrative review
title_full Antimicrobial properties of the mushroom Agaricus blazei – integrative review
title_fullStr Antimicrobial properties of the mushroom Agaricus blazei – integrative review
title_full_unstemmed Antimicrobial properties of the mushroom Agaricus blazei – integrative review
title_sort Antimicrobial properties of the mushroom Agaricus blazei – integrative review
author Lima,Cristiane U.J.O.
author_facet Lima,Cristiane U.J.O.
Gris,Eliana F.
Karnikowski,Margô G.O.
author_role author
author2 Gris,Eliana F.
Karnikowski,Margô G.O.
author2_role author
author
dc.contributor.author.fl_str_mv Lima,Cristiane U.J.O.
Gris,Eliana F.
Karnikowski,Margô G.O.
dc.subject.por.fl_str_mv Agaricus blazei
Antibiotic
Antimicrobial
Antimicrobial agents
Infection
topic Agaricus blazei
Antibiotic
Antimicrobial
Antimicrobial agents
Infection
description ABSTRACT Infectious diseases associated with antimicrobial resistance are considered to represent an important public health problem. In this regard, the mushroom Agaricus blazei Murrill contains several bioactive substances that promote significant functional properties, among them, antimicrobial activity, which has attracted the interest of the scientific community. Thus, the aim of this study was to determine whether evidence of the antimicrobial action of A. blazei has been reported in the literature. In this integrative review, manuscripts held in research databases available online were examined with a view to answering the question “Does the mushroom A. blazei exert antimicrobial activity against Gram-negative and/or Gram-positive bacteria?” Only eight scientific articles that have addressed the antimicrobial properties of A. blazei, in vitro and in vivo, were found, all characterized as pre-clinical, i.e., with level VII evidence. Most authors have found that the A. blazei extract promotes an antimicrobial effect against peritonitis, as well as deadly oral infections, especially those caused by Gram-positive bacteria. However, the scientific data currently available are not sufficient to verify the antimicrobial aspect of the mushroom A. blazei and thus further investigation is required.
publishDate 2016
dc.date.none.fl_str_mv 2016-12-01
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2016000600780
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjp.2016.05.013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.26 n.6 2016
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
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reponame_str Revista Brasileira de Farmacognosia (Online)
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