Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000500451 |
Resumo: | ABSTRACTThe antimicrobial activity of the myrsinoic acid A isolated from Myrsine coriacea (Sw.) R.Br. ex Roem. & Schult., Primulaceae, and a two semi-synthetics derivatives was tested against Bacillus subtilis, Escherichia coli, Salmonella enterica subsp. enterica serovar typhi, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Micrococcus luteus, Candida albicans, Candida krusei and Candida tropicalis. The microdilution method was used for the determination of the minimum inhibitory concentration during evaluation of the antimicrobial activity. The myrsinoic acid A showed no activity against the selected microorganisms but the hydrogenated and acetylated derivatives were active against B. subtilis, E. coli, S. aureus and P. aeruginosa. |
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Revista Brasileira de Farmacognosia (Online) |
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Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivativesMyrsine coriaceAntimicrobial activityPrimulaceaeMyrsinoic acid AABSTRACTThe antimicrobial activity of the myrsinoic acid A isolated from Myrsine coriacea (Sw.) R.Br. ex Roem. & Schult., Primulaceae, and a two semi-synthetics derivatives was tested against Bacillus subtilis, Escherichia coli, Salmonella enterica subsp. enterica serovar typhi, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Micrococcus luteus, Candida albicans, Candida krusei and Candida tropicalis. The microdilution method was used for the determination of the minimum inhibitory concentration during evaluation of the antimicrobial activity. The myrsinoic acid A showed no activity against the selected microorganisms but the hydrogenated and acetylated derivatives were active against B. subtilis, E. coli, S. aureus and P. aeruginosa.Sociedade Brasileira de Farmacognosia2015-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000500451Revista Brasileira de Farmacognosia v.25 n.5 2015reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2015.07.023info:eu-repo/semantics/openAccessBurger,Marcela Carmen de MeloTerezan,Ana PaulaCunha,Gracielle Silva de OliveiraFernandes,Joao BatistaSilva,Maria Fatima das Graças Fernandes daVieira,Paulo CezarMenezes,Antonio Carlos Severoeng2015-11-11T00:00:00Zoai:scielo:S0102-695X2015000500451Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2015-11-11T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
title |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
spellingShingle |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives Burger,Marcela Carmen de Melo Myrsine coriace Antimicrobial activity Primulaceae Myrsinoic acid A |
title_short |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
title_full |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
title_fullStr |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
title_full_unstemmed |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
title_sort |
Antimicrobial activity of the myrsinoic acid A from Myrsine coriacea and the semi-synthetic derivatives |
author |
Burger,Marcela Carmen de Melo |
author_facet |
Burger,Marcela Carmen de Melo Terezan,Ana Paula Cunha,Gracielle Silva de Oliveira Fernandes,Joao Batista Silva,Maria Fatima das Graças Fernandes da Vieira,Paulo Cezar Menezes,Antonio Carlos Severo |
author_role |
author |
author2 |
Terezan,Ana Paula Cunha,Gracielle Silva de Oliveira Fernandes,Joao Batista Silva,Maria Fatima das Graças Fernandes da Vieira,Paulo Cezar Menezes,Antonio Carlos Severo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Burger,Marcela Carmen de Melo Terezan,Ana Paula Cunha,Gracielle Silva de Oliveira Fernandes,Joao Batista Silva,Maria Fatima das Graças Fernandes da Vieira,Paulo Cezar Menezes,Antonio Carlos Severo |
dc.subject.por.fl_str_mv |
Myrsine coriace Antimicrobial activity Primulaceae Myrsinoic acid A |
topic |
Myrsine coriace Antimicrobial activity Primulaceae Myrsinoic acid A |
description |
ABSTRACTThe antimicrobial activity of the myrsinoic acid A isolated from Myrsine coriacea (Sw.) R.Br. ex Roem. & Schult., Primulaceae, and a two semi-synthetics derivatives was tested against Bacillus subtilis, Escherichia coli, Salmonella enterica subsp. enterica serovar typhi, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Micrococcus luteus, Candida albicans, Candida krusei and Candida tropicalis. The microdilution method was used for the determination of the minimum inhibitory concentration during evaluation of the antimicrobial activity. The myrsinoic acid A showed no activity against the selected microorganisms but the hydrogenated and acetylated derivatives were active against B. subtilis, E. coli, S. aureus and P. aeruginosa. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000500451 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000500451 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjp.2015.07.023 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.25 n.5 2015 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122469607538688 |