Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation

Detalhes bibliográficos
Autor(a) principal: Peixoto,Maria Paula G.
Data de Publicação: 2013
Outros Autores: Freitas,Luís A. P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000100020
Resumo: Aqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried extracts showed in vivo antihyperglycaemic and in vitro scavenger activity comparable to the lyophilized extract. Thus, experimental data indicates that the extract from S. cumini has a relevant activity and that spray-drying could be adequately used to perform the technological processing of S. cumini fluid extracts.
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spelling Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluationEugenia jambolanaDPPHexperimental diabetesflavonoidspolyphenolsspray-dryingAqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried extracts showed in vivo antihyperglycaemic and in vitro scavenger activity comparable to the lyophilized extract. Thus, experimental data indicates that the extract from S. cumini has a relevant activity and that spray-drying could be adequately used to perform the technological processing of S. cumini fluid extracts.Sociedade Brasileira de Farmacognosia2013-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000100020Revista Brasileira de Farmacognosia v.23 n.1 2013reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2012005000124info:eu-repo/semantics/openAccessPeixoto,Maria Paula G.Freitas,Luís A. P.eng2013-03-28T00:00:00Zoai:scielo:S0102-695X2013000100020Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2013-03-28T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
title Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
spellingShingle Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
Peixoto,Maria Paula G.
Eugenia jambolana
DPPH
experimental diabetes
flavonoids
polyphenols
spray-drying
title_short Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
title_full Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
title_fullStr Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
title_full_unstemmed Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
title_sort Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation
author Peixoto,Maria Paula G.
author_facet Peixoto,Maria Paula G.
Freitas,Luís A. P.
author_role author
author2 Freitas,Luís A. P.
author2_role author
dc.contributor.author.fl_str_mv Peixoto,Maria Paula G.
Freitas,Luís A. P.
dc.subject.por.fl_str_mv Eugenia jambolana
DPPH
experimental diabetes
flavonoids
polyphenols
spray-drying
topic Eugenia jambolana
DPPH
experimental diabetes
flavonoids
polyphenols
spray-drying
description Aqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried extracts showed in vivo antihyperglycaemic and in vitro scavenger activity comparable to the lyophilized extract. Thus, experimental data indicates that the extract from S. cumini has a relevant activity and that spray-drying could be adequately used to perform the technological processing of S. cumini fluid extracts.
publishDate 2013
dc.date.none.fl_str_mv 2013-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000100020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000100020
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2012005000124
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.23 n.1 2013
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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