A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Farmacognosia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2014000400419 |
Resumo: | Diarrhea is a serious public health problem in Mexico and other countries. A widely used alternative in the treatment of diarrhea is the use of herbal medicines. Infusions of chamomile and star anise possess anti-inflammatory and antimotility properties that could help alleviate gastrointestinal disorders. The aim of this study was to determine the effect of the mixture of chamomile and star anise infusions on gastrointestinal activity in mice. A gastrointestinal assessment of the mixture of chamomile and star anise was carried out in mice, and the percentage of advance of administered activated carbon through the intestinal tract of the animals was measured. Furthermore, the diarrhea model was induced with castor oil. The infusions were prepared using a mix with a 50:50 ratio of the herbs, and were administered at Mix-10, 20, 40 and 80 (mg/kg) orally. The results indicate that Mix-40 and Mix-80 decreased the completion percentage of the activated carbon, delayed the appearance of diarrhea and decreased the number of evacuations in comparison with the control group. This suggests that the combination of chamomile and star anise can be used as an alternative antidiarrheal treatment. |
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A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in miceChamomileStar aniseIntestinal motilityCastor oilAntidiarrhealDiarrhea is a serious public health problem in Mexico and other countries. A widely used alternative in the treatment of diarrhea is the use of herbal medicines. Infusions of chamomile and star anise possess anti-inflammatory and antimotility properties that could help alleviate gastrointestinal disorders. The aim of this study was to determine the effect of the mixture of chamomile and star anise infusions on gastrointestinal activity in mice. A gastrointestinal assessment of the mixture of chamomile and star anise was carried out in mice, and the percentage of advance of administered activated carbon through the intestinal tract of the animals was measured. Furthermore, the diarrhea model was induced with castor oil. The infusions were prepared using a mix with a 50:50 ratio of the herbs, and were administered at Mix-10, 20, 40 and 80 (mg/kg) orally. The results indicate that Mix-40 and Mix-80 decreased the completion percentage of the activated carbon, delayed the appearance of diarrhea and decreased the number of evacuations in comparison with the control group. This suggests that the combination of chamomile and star anise can be used as an alternative antidiarrheal treatment.Sociedade Brasileira de Farmacognosia2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2014000400419Revista Brasileira de Farmacognosia v.24 n.4 2014reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1016/j.bjp.2014.07.016info:eu-repo/semantics/openAccessDíaz,AlfonsoVargas-Perez,IzelAguilar-Cruz,LidiaCalva-Rodríguez,RobertoTreviño,SamuelVenegas,BereniceContreras-Mora,Irma Rosalíaeng2015-10-09T00:00:00Zoai:scielo:S0102-695X2014000400419Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2015-10-09T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false |
dc.title.none.fl_str_mv |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
title |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
spellingShingle |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice Díaz,Alfonso Chamomile Star anise Intestinal motility Castor oil Antidiarrheal |
title_short |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
title_full |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
title_fullStr |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
title_full_unstemmed |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
title_sort |
A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice |
author |
Díaz,Alfonso |
author_facet |
Díaz,Alfonso Vargas-Perez,Izel Aguilar-Cruz,Lidia Calva-Rodríguez,Roberto Treviño,Samuel Venegas,Berenice Contreras-Mora,Irma Rosalía |
author_role |
author |
author2 |
Vargas-Perez,Izel Aguilar-Cruz,Lidia Calva-Rodríguez,Roberto Treviño,Samuel Venegas,Berenice Contreras-Mora,Irma Rosalía |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Díaz,Alfonso Vargas-Perez,Izel Aguilar-Cruz,Lidia Calva-Rodríguez,Roberto Treviño,Samuel Venegas,Berenice Contreras-Mora,Irma Rosalía |
dc.subject.por.fl_str_mv |
Chamomile Star anise Intestinal motility Castor oil Antidiarrheal |
topic |
Chamomile Star anise Intestinal motility Castor oil Antidiarrheal |
description |
Diarrhea is a serious public health problem in Mexico and other countries. A widely used alternative in the treatment of diarrhea is the use of herbal medicines. Infusions of chamomile and star anise possess anti-inflammatory and antimotility properties that could help alleviate gastrointestinal disorders. The aim of this study was to determine the effect of the mixture of chamomile and star anise infusions on gastrointestinal activity in mice. A gastrointestinal assessment of the mixture of chamomile and star anise was carried out in mice, and the percentage of advance of administered activated carbon through the intestinal tract of the animals was measured. Furthermore, the diarrhea model was induced with castor oil. The infusions were prepared using a mix with a 50:50 ratio of the herbs, and were administered at Mix-10, 20, 40 and 80 (mg/kg) orally. The results indicate that Mix-40 and Mix-80 decreased the completion percentage of the activated carbon, delayed the appearance of diarrhea and decreased the number of evacuations in comparison with the control group. This suggests that the combination of chamomile and star anise can be used as an alternative antidiarrheal treatment. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2014000400419 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2014000400419 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjp.2014.07.016 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Farmacognosia |
dc.source.none.fl_str_mv |
Revista Brasileira de Farmacognosia v.24 n.4 2014 reponame:Revista Brasileira de Farmacognosia (Online) instname:Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA |
instname_str |
Sociedade Brasileira de Farmacognosia (SBFgnosia) |
instacron_str |
SBFGNOSIA |
institution |
SBFGNOSIA |
reponame_str |
Revista Brasileira de Farmacognosia (Online) |
collection |
Revista Brasileira de Farmacognosia (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia) |
repository.mail.fl_str_mv |
rbgnosia@ltf.ufpb.br |
_version_ |
1752122469148262400 |