Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba

Detalhes bibliográficos
Autor(a) principal: Tilaoui,Mounir
Data de Publicação: 2011
Outros Autores: Mouse,Hassan Ait, Jaafari,Abdeslam, Aboufatima,Rachida, Chait,Abderrahman, Zyad,Abdelmajid
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400031
Resumo: Artemisia herba-alba Asso., Asteraceae, is widely used in Morrocan folk medicine for the treatment of different health disorders. However, no scientific or medical studies were carried out to assess the cytotoxicity of A. herba-alba essential oil against cancer cell lines. In this study, eighteen volatile compounds were identified by GC-MS analysis of the essential oil obtained from the plant's aerial parts. The main volatile constituent in A. herba-alba was found to be a monoterpene, Verbenol, contributing to about 22% of the total volatile components. The essential oil showed significant antiproliferative activity against the acute lymphoblastic leukaemia (CEM) cell line, with 3 µg/mL as IC50 value. The anticancer bioactivity of Moroccan A. herba-alba essential oil is described here for the first time.
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spelling Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-albaaerial partsanticancer activityArtemisia herba-albacompositionessential oilArtemisia herba-alba Asso., Asteraceae, is widely used in Morrocan folk medicine for the treatment of different health disorders. However, no scientific or medical studies were carried out to assess the cytotoxicity of A. herba-alba essential oil against cancer cell lines. In this study, eighteen volatile compounds were identified by GC-MS analysis of the essential oil obtained from the plant's aerial parts. The main volatile constituent in A. herba-alba was found to be a monoterpene, Verbenol, contributing to about 22% of the total volatile components. The essential oil showed significant antiproliferative activity against the acute lymphoblastic leukaemia (CEM) cell line, with 3 µg/mL as IC50 value. The anticancer bioactivity of Moroccan A. herba-alba essential oil is described here for the first time.Sociedade Brasileira de Farmacognosia2011-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400031Revista Brasileira de Farmacognosia v.21 n.4 2011reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2011005000114info:eu-repo/semantics/openAccessTilaoui,MounirMouse,Hassan AitJaafari,AbdeslamAboufatima,RachidaChait,AbderrahmanZyad,Abdelmajideng2011-08-15T00:00:00Zoai:scielo:S0102-695X2011000400031Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2011-08-15T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
title Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
spellingShingle Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
Tilaoui,Mounir
aerial parts
anticancer activity
Artemisia herba-alba
composition
essential oil
title_short Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
title_full Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
title_fullStr Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
title_full_unstemmed Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
title_sort Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
author Tilaoui,Mounir
author_facet Tilaoui,Mounir
Mouse,Hassan Ait
Jaafari,Abdeslam
Aboufatima,Rachida
Chait,Abderrahman
Zyad,Abdelmajid
author_role author
author2 Mouse,Hassan Ait
Jaafari,Abdeslam
Aboufatima,Rachida
Chait,Abderrahman
Zyad,Abdelmajid
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Tilaoui,Mounir
Mouse,Hassan Ait
Jaafari,Abdeslam
Aboufatima,Rachida
Chait,Abderrahman
Zyad,Abdelmajid
dc.subject.por.fl_str_mv aerial parts
anticancer activity
Artemisia herba-alba
composition
essential oil
topic aerial parts
anticancer activity
Artemisia herba-alba
composition
essential oil
description Artemisia herba-alba Asso., Asteraceae, is widely used in Morrocan folk medicine for the treatment of different health disorders. However, no scientific or medical studies were carried out to assess the cytotoxicity of A. herba-alba essential oil against cancer cell lines. In this study, eighteen volatile compounds were identified by GC-MS analysis of the essential oil obtained from the plant's aerial parts. The main volatile constituent in A. herba-alba was found to be a monoterpene, Verbenol, contributing to about 22% of the total volatile components. The essential oil showed significant antiproliferative activity against the acute lymphoblastic leukaemia (CEM) cell line, with 3 µg/mL as IC50 value. The anticancer bioactivity of Moroccan A. herba-alba essential oil is described here for the first time.
publishDate 2011
dc.date.none.fl_str_mv 2011-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400031
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2011000400031
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2011005000114
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.21 n.4 2011
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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