Bioactivity of two Turkish endemic Centaurea species, and their major constituents

Detalhes bibliográficos
Autor(a) principal: Shoeb,Mohammad
Data de Publicação: 2007
Outros Autores: MacManus,Stephen M., Jaspars,Marcel, Kong-Thoo-Lin,Paul, Nahar,Lutfun, Celik,Sezgin, Sarker,Satyajit D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200003
Resumo: The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
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spelling Bioactivity of two Turkish endemic Centaurea species, and their major constituentsCentaurea urvillei subs. armataCentaurea mucroniferaAsteraceaeCompositaelignanarctiinmatairesinosideDPPHMTTbrine shrimp lethality assayThe antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.Sociedade Brasileira de Farmacognosia2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200003Revista Brasileira de Farmacognosia v.17 n.2 2007reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2007000200003info:eu-repo/semantics/openAccessShoeb,MohammadMacManus,Stephen M.Jaspars,MarcelKong-Thoo-Lin,PaulNahar,LutfunCelik,SezginSarker,Satyajit D.eng2007-07-20T00:00:00Zoai:scielo:S0102-695X2007000200003Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2007-07-20T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Bioactivity of two Turkish endemic Centaurea species, and their major constituents
title Bioactivity of two Turkish endemic Centaurea species, and their major constituents
spellingShingle Bioactivity of two Turkish endemic Centaurea species, and their major constituents
Shoeb,Mohammad
Centaurea urvillei subs. armata
Centaurea mucronifera
Asteraceae
Compositae
lignan
arctiin
matairesinoside
DPPH
MTT
brine shrimp lethality assay
title_short Bioactivity of two Turkish endemic Centaurea species, and their major constituents
title_full Bioactivity of two Turkish endemic Centaurea species, and their major constituents
title_fullStr Bioactivity of two Turkish endemic Centaurea species, and their major constituents
title_full_unstemmed Bioactivity of two Turkish endemic Centaurea species, and their major constituents
title_sort Bioactivity of two Turkish endemic Centaurea species, and their major constituents
author Shoeb,Mohammad
author_facet Shoeb,Mohammad
MacManus,Stephen M.
Jaspars,Marcel
Kong-Thoo-Lin,Paul
Nahar,Lutfun
Celik,Sezgin
Sarker,Satyajit D.
author_role author
author2 MacManus,Stephen M.
Jaspars,Marcel
Kong-Thoo-Lin,Paul
Nahar,Lutfun
Celik,Sezgin
Sarker,Satyajit D.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Shoeb,Mohammad
MacManus,Stephen M.
Jaspars,Marcel
Kong-Thoo-Lin,Paul
Nahar,Lutfun
Celik,Sezgin
Sarker,Satyajit D.
dc.subject.por.fl_str_mv Centaurea urvillei subs. armata
Centaurea mucronifera
Asteraceae
Compositae
lignan
arctiin
matairesinoside
DPPH
MTT
brine shrimp lethality assay
topic Centaurea urvillei subs. armata
Centaurea mucronifera
Asteraceae
Compositae
lignan
arctiin
matairesinoside
DPPH
MTT
brine shrimp lethality assay
description The antioxidant activity, general toxicity and cytotoxicity of the methanol extracts of Centaurea urvillei subs. armata and C. mucronifera have been assessed, respectively, by the DPPH assay, the brine shrimp lethality and the MTT cytotoxicity assays. The reversed-phase HPLC analysis of the methanol extracts afforded two bioactive dibenzylbutyrolactone-type lignans, matairesinoside (1) and arctiin (2). The structures of these lignans were elucidated by comprehensive spectroscopic analyses as well as by the direct comparison of experimental data with respective literature data.
publishDate 2007
dc.date.none.fl_str_mv 2007-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2007000200003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.17 n.2 2007
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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