Biological screening of Amaranthus retroflexus L. (Amaranthaceae)

Detalhes bibliográficos
Autor(a) principal: Amoli,Jamileh Salar
Data de Publicação: 2009
Outros Autores: Sadighara,Parisa, Barin,Abbas, Yazdani,Azam, Satari,Saeed
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000400019
Resumo: Bioassays are required for the determination of the total toxicity of Amaranthus retroflexus L. (Amaranthaceae) or "redroot pigweed". Therefore, the plant extract has been tested for bioactivity in Artemia salina and cytotoxicity against bovine kidney cells. The LD50 values for Artemia salina were measured at 1700 ppm. The bovine kidney cells were exposed to various concentrations of the plant extracts (100 ppm-0.1 ppm). After treating with 100 and 0.1 ppm for 24 h, the cells viability were reduced by about 49% and 35% respectively in MTT viability assay. The study confirmed that Amaranthus retroflexus has a cytotoxic effect and more specific to renal cells.
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spelling Biological screening of Amaranthus retroflexus L. (Amaranthaceae)Amaranthus retroflexusAmaranthaceaebrine shrimp lethality assayMTT assayBioassays are required for the determination of the total toxicity of Amaranthus retroflexus L. (Amaranthaceae) or "redroot pigweed". Therefore, the plant extract has been tested for bioactivity in Artemia salina and cytotoxicity against bovine kidney cells. The LD50 values for Artemia salina were measured at 1700 ppm. The bovine kidney cells were exposed to various concentrations of the plant extracts (100 ppm-0.1 ppm). After treating with 100 and 0.1 ppm for 24 h, the cells viability were reduced by about 49% and 35% respectively in MTT viability assay. The study confirmed that Amaranthus retroflexus has a cytotoxic effect and more specific to renal cells.Sociedade Brasileira de Farmacognosia2009-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000400019Revista Brasileira de Farmacognosia v.19 n.2b 2009reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2009000400019info:eu-repo/semantics/openAccessAmoli,Jamileh SalarSadighara,ParisaBarin,AbbasYazdani,AzamSatari,Saeedeng2009-11-24T00:00:00Zoai:scielo:S0102-695X2009000400019Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2009-11-24T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
title Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
spellingShingle Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
Amoli,Jamileh Salar
Amaranthus retroflexus
Amaranthaceae
brine shrimp lethality assay
MTT assay
title_short Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
title_full Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
title_fullStr Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
title_full_unstemmed Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
title_sort Biological screening of Amaranthus retroflexus L. (Amaranthaceae)
author Amoli,Jamileh Salar
author_facet Amoli,Jamileh Salar
Sadighara,Parisa
Barin,Abbas
Yazdani,Azam
Satari,Saeed
author_role author
author2 Sadighara,Parisa
Barin,Abbas
Yazdani,Azam
Satari,Saeed
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Amoli,Jamileh Salar
Sadighara,Parisa
Barin,Abbas
Yazdani,Azam
Satari,Saeed
dc.subject.por.fl_str_mv Amaranthus retroflexus
Amaranthaceae
brine shrimp lethality assay
MTT assay
topic Amaranthus retroflexus
Amaranthaceae
brine shrimp lethality assay
MTT assay
description Bioassays are required for the determination of the total toxicity of Amaranthus retroflexus L. (Amaranthaceae) or "redroot pigweed". Therefore, the plant extract has been tested for bioactivity in Artemia salina and cytotoxicity against bovine kidney cells. The LD50 values for Artemia salina were measured at 1700 ppm. The bovine kidney cells were exposed to various concentrations of the plant extracts (100 ppm-0.1 ppm). After treating with 100 and 0.1 ppm for 24 h, the cells viability were reduced by about 49% and 35% respectively in MTT viability assay. The study confirmed that Amaranthus retroflexus has a cytotoxic effect and more specific to renal cells.
publishDate 2009
dc.date.none.fl_str_mv 2009-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000400019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000400019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2009000400019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.19 n.2b 2009
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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