Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice

Bibliographic Details
Main Author: Sousa,Damião P. de
Publication Date: 2007
Other Authors: Nóbrega,Franklin F. F., Claudino,Fladmir S., Almeida,Reinaldo N. de, Leite,José R., Mattei,Rita
Format: Article
Language: eng
Source: Revista Brasileira de Farmacognosia (Online)
Download full: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200006
Summary: The monoterpene alpha,beta-epoxy-carvone (EC) in doses of 200, 300 or 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group, up to 120 minutes after the administration. The doses of 300 or 400 mg/kg had induced a significant increase of in the sleeping time of animals not having modified, however, the latency. The EC in the dose of 400 mg/kg reduced the remaining time of the animals on the rotating rod (Rotarod test). These results suggest a possible central effect.
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spelling Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in micePharmacological effectsessential oilmonoterpenealpha,beta-epoxy-carvonemiceThe monoterpene alpha,beta-epoxy-carvone (EC) in doses of 200, 300 or 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group, up to 120 minutes after the administration. The doses of 300 or 400 mg/kg had induced a significant increase of in the sleeping time of animals not having modified, however, the latency. The EC in the dose of 400 mg/kg reduced the remaining time of the animals on the rotating rod (Rotarod test). These results suggest a possible central effect.Sociedade Brasileira de Farmacognosia2007-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200006Revista Brasileira de Farmacognosia v.17 n.2 2007reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2007000200006info:eu-repo/semantics/openAccessSousa,Damião P. deNóbrega,Franklin F. F.Claudino,Fladmir S.Almeida,Reinaldo N. deLeite,José R.Mattei,Ritaeng2007-07-20T00:00:00Zoai:scielo:S0102-695X2007000200006Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2007-07-20T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
title Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
spellingShingle Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
Sousa,Damião P. de
Pharmacological effects
essential oil
monoterpene
alpha,beta-epoxy-carvone
mice
title_short Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
title_full Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
title_fullStr Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
title_full_unstemmed Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
title_sort Pharmacological effects of the monoterpene alpha,beta-epoxy-carvone in mice
author Sousa,Damião P. de
author_facet Sousa,Damião P. de
Nóbrega,Franklin F. F.
Claudino,Fladmir S.
Almeida,Reinaldo N. de
Leite,José R.
Mattei,Rita
author_role author
author2 Nóbrega,Franklin F. F.
Claudino,Fladmir S.
Almeida,Reinaldo N. de
Leite,José R.
Mattei,Rita
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa,Damião P. de
Nóbrega,Franklin F. F.
Claudino,Fladmir S.
Almeida,Reinaldo N. de
Leite,José R.
Mattei,Rita
dc.subject.por.fl_str_mv Pharmacological effects
essential oil
monoterpene
alpha,beta-epoxy-carvone
mice
topic Pharmacological effects
essential oil
monoterpene
alpha,beta-epoxy-carvone
mice
description The monoterpene alpha,beta-epoxy-carvone (EC) in doses of 200, 300 or 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group, up to 120 minutes after the administration. The doses of 300 or 400 mg/kg had induced a significant increase of in the sleeping time of animals not having modified, however, the latency. The EC in the dose of 400 mg/kg reduced the remaining time of the animals on the rotating rod (Rotarod test). These results suggest a possible central effect.
publishDate 2007
dc.date.none.fl_str_mv 2007-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2007000200006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2007000200006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.17 n.2 2007
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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