Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)

Detalhes bibliográficos
Autor(a) principal: Silva,Nina C. B.
Data de Publicação: 2009
Outros Autores: Esquibel,Maria A., Alves,Iura M., Velozo,Eudes S., Almeida,Mara Z., Santos,Jaci E. S., Campos-Buzzi,Fátima de, Meira,Aleandra V., Cechinel-Filho,Valdir
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Farmacognosia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000100011
Resumo: In this study, we investigated the analgesic activity of crude aqueous and methanol extracts obtained from Abarema cochliacarpos bark in mice, and analyzed its phytochemical profile. All the extracts exhibited analgesic properties against the writhing test in mice, but the aqueous and methanol extracts were more active, and more potent than two known analgesic and anti-inflammatory drugs used as reference. They were also active against the capsaicin-model, but inactive when evaluated in the hot-plate test. Phytochemical studies revealed the presence of saponins, catechins, tannins, phenols and anthraquinones.
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spelling Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)Abarema cochliacarposanalgesic effectsmedicinal plantytochemical profileIn this study, we investigated the analgesic activity of crude aqueous and methanol extracts obtained from Abarema cochliacarpos bark in mice, and analyzed its phytochemical profile. All the extracts exhibited analgesic properties against the writhing test in mice, but the aqueous and methanol extracts were more active, and more potent than two known analgesic and anti-inflammatory drugs used as reference. They were also active against the capsaicin-model, but inactive when evaluated in the hot-plate test. Phytochemical studies revealed the presence of saponins, catechins, tannins, phenols and anthraquinones.Sociedade Brasileira de Farmacognosia2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000100011Revista Brasileira de Farmacognosia v.19 n.1a 2009reponame:Revista Brasileira de Farmacognosia (Online)instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)instacron:SBFGNOSIA10.1590/S0102-695X2009000100011info:eu-repo/semantics/openAccessSilva,Nina C. B.Esquibel,Maria A.Alves,Iura M.Velozo,Eudes S.Almeida,Mara Z.Santos,Jaci E. S.Campos-Buzzi,Fátima deMeira,Aleandra V.Cechinel-Filho,Valdireng2009-08-11T00:00:00Zoai:scielo:S0102-695X2009000100011Revistahttp://www.sbfgnosia.org.br/revista/https://old.scielo.br/oai/scielo-oai.phprbgnosia@ltf.ufpb.br1981-528X0102-695Xopendoar:2009-08-11T00:00Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)false
dc.title.none.fl_str_mv Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
title Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
spellingShingle Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
Silva,Nina C. B.
Abarema cochliacarpos
analgesic effects
medicinal plant
ytochemical profile
title_short Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
title_full Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
title_fullStr Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
title_full_unstemmed Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
title_sort Antinociceptive effects of Abarema cochliacarpos (B.A. Gomes) Barneby & J.W.Grimes (Mimosaceae)
author Silva,Nina C. B.
author_facet Silva,Nina C. B.
Esquibel,Maria A.
Alves,Iura M.
Velozo,Eudes S.
Almeida,Mara Z.
Santos,Jaci E. S.
Campos-Buzzi,Fátima de
Meira,Aleandra V.
Cechinel-Filho,Valdir
author_role author
author2 Esquibel,Maria A.
Alves,Iura M.
Velozo,Eudes S.
Almeida,Mara Z.
Santos,Jaci E. S.
Campos-Buzzi,Fátima de
Meira,Aleandra V.
Cechinel-Filho,Valdir
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,Nina C. B.
Esquibel,Maria A.
Alves,Iura M.
Velozo,Eudes S.
Almeida,Mara Z.
Santos,Jaci E. S.
Campos-Buzzi,Fátima de
Meira,Aleandra V.
Cechinel-Filho,Valdir
dc.subject.por.fl_str_mv Abarema cochliacarpos
analgesic effects
medicinal plant
ytochemical profile
topic Abarema cochliacarpos
analgesic effects
medicinal plant
ytochemical profile
description In this study, we investigated the analgesic activity of crude aqueous and methanol extracts obtained from Abarema cochliacarpos bark in mice, and analyzed its phytochemical profile. All the extracts exhibited analgesic properties against the writhing test in mice, but the aqueous and methanol extracts were more active, and more potent than two known analgesic and anti-inflammatory drugs used as reference. They were also active against the capsaicin-model, but inactive when evaluated in the hot-plate test. Phytochemical studies revealed the presence of saponins, catechins, tannins, phenols and anthraquinones.
publishDate 2009
dc.date.none.fl_str_mv 2009-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000100011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000100011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-695X2009000100011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv Revista Brasileira de Farmacognosia v.19 n.1a 2009
reponame:Revista Brasileira de Farmacognosia (Online)
instname:Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
instname_str Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron_str SBFGNOSIA
institution SBFGNOSIA
reponame_str Revista Brasileira de Farmacognosia (Online)
collection Revista Brasileira de Farmacognosia (Online)
repository.name.fl_str_mv Revista Brasileira de Farmacognosia (Online) - Sociedade Brasileira de Farmacognosia (SBFgnosia)
repository.mail.fl_str_mv rbgnosia@ltf.ufpb.br
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