A simple method for the detection of recombinogenic substances in filamentous fungi

Detalhes bibliográficos
Autor(a) principal: Baracho,Marta dos Santos
Data de Publicação: 2000
Outros Autores: Baracho,Ivanhoé Rodrigues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200042
Resumo: Several tests are available for detecting mutagenic and recombinogenic products in fungi. Since fungi are eukaryotic, these tests permit the detection of substances that produce chromosomal aberrations, or that are recombinogenic. We have developed a new method for testing substances that affect fungal stability using a duplication strain of Aspergillus nidulans and circular statistics for data analysis. The fungus was inoculated on the center of Petri dishes and the substance to be tested was applied to a defined area of the dish. Position of resulting sectors was measured by an angle and the data were analyzed by the Rayleigh test. Extensive testing with different compounds showed this method to be rapid and efficient for screening recombinogenic substances.
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spelling A simple method for the detection of recombinogenic substances in filamentous fungiSeveral tests are available for detecting mutagenic and recombinogenic products in fungi. Since fungi are eukaryotic, these tests permit the detection of substances that produce chromosomal aberrations, or that are recombinogenic. We have developed a new method for testing substances that affect fungal stability using a duplication strain of Aspergillus nidulans and circular statistics for data analysis. The fungus was inoculated on the center of Petri dishes and the substance to be tested was applied to a defined area of the dish. Position of resulting sectors was measured by an angle and the data were analyzed by the Rayleigh test. Extensive testing with different compounds showed this method to be rapid and efficient for screening recombinogenic substances.Sociedade Brasileira de Genética2000-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200042Genetics and Molecular Biology v.23 n.2 2000reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572000000200042info:eu-repo/semantics/openAccessBaracho,Marta dos SantosBaracho,Ivanhoé Rodrigueseng2000-09-22T00:00:00Zoai:scielo:S1415-47572000000200042Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2000-09-22T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv A simple method for the detection of recombinogenic substances in filamentous fungi
title A simple method for the detection of recombinogenic substances in filamentous fungi
spellingShingle A simple method for the detection of recombinogenic substances in filamentous fungi
Baracho,Marta dos Santos
title_short A simple method for the detection of recombinogenic substances in filamentous fungi
title_full A simple method for the detection of recombinogenic substances in filamentous fungi
title_fullStr A simple method for the detection of recombinogenic substances in filamentous fungi
title_full_unstemmed A simple method for the detection of recombinogenic substances in filamentous fungi
title_sort A simple method for the detection of recombinogenic substances in filamentous fungi
author Baracho,Marta dos Santos
author_facet Baracho,Marta dos Santos
Baracho,Ivanhoé Rodrigues
author_role author
author2 Baracho,Ivanhoé Rodrigues
author2_role author
dc.contributor.author.fl_str_mv Baracho,Marta dos Santos
Baracho,Ivanhoé Rodrigues
description Several tests are available for detecting mutagenic and recombinogenic products in fungi. Since fungi are eukaryotic, these tests permit the detection of substances that produce chromosomal aberrations, or that are recombinogenic. We have developed a new method for testing substances that affect fungal stability using a duplication strain of Aspergillus nidulans and circular statistics for data analysis. The fungus was inoculated on the center of Petri dishes and the substance to be tested was applied to a defined area of the dish. Position of resulting sectors was measured by an angle and the data were analyzed by the Rayleigh test. Extensive testing with different compounds showed this method to be rapid and efficient for screening recombinogenic substances.
publishDate 2000
dc.date.none.fl_str_mv 2000-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200042
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200042
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572000000200042
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.23 n.2 2000
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
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instname_str Sociedade Brasileira de Genética (SBG)
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reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
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