Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)

Detalhes bibliográficos
Autor(a) principal: Borgonovo,Tamara
Data de Publicação: 2005
Outros Autores: Ribeiro,Enilze M.S.F., Cornélio,Déborah Afonso, Schmid-Braz,Ana Teresa, Jamur,Valderez Ravaglio, Wuicik,Lismeri, Veiga,Loraine Beatriz Acosta, Ehmke,Néria A. Maia, Pasquini,Ricardo, Cavalli,Iglenir João
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500002
Resumo: Bone marrow cytogenetic studies were performed on 93 patients with primary myelodysplastic syndrome (MDS) diagnosed at the Clinical Hospital of the Federal University of Paraná, Brazil. Chromosomal alterations were observed in 69% of the patients. Monosomy of chromosome 7, deletions of 7q, 5q, 12p and 20q, rearrangements of 11q23 and trisomies of chromosomes 8 and 21 were the most frequent abnormalities observed. Among adult patients the most frequent aberrations were rearrangements of 11q23 and 12p deletions. In the pediatric group, 5q deletions and monosomy of chromosome 7 were the most common alterations.
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spelling Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)hematological disordersmyelodysplasiascancer cytogeneticsBone marrow cytogenetic studies were performed on 93 patients with primary myelodysplastic syndrome (MDS) diagnosed at the Clinical Hospital of the Federal University of Paraná, Brazil. Chromosomal alterations were observed in 69% of the patients. Monosomy of chromosome 7, deletions of 7q, 5q, 12p and 20q, rearrangements of 11q23 and trisomies of chromosomes 8 and 21 were the most frequent abnormalities observed. Among adult patients the most frequent aberrations were rearrangements of 11q23 and 12p deletions. In the pediatric group, 5q deletions and monosomy of chromosome 7 were the most common alterations.Sociedade Brasileira de Genética2005-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500002Genetics and Molecular Biology v.28 n.4 2005reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47572005000500002info:eu-repo/semantics/openAccessBorgonovo,TamaraRibeiro,Enilze M.S.F.Cornélio,Déborah AfonsoSchmid-Braz,Ana TeresaJamur,Valderez RavaglioWuicik,LismeriVeiga,Loraine Beatriz AcostaEhmke,Néria A. MaiaPasquini,RicardoCavalli,Iglenir Joãoeng2006-02-03T00:00:00Zoai:scielo:S1415-47572005000500002Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2006-02-03T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
title Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
spellingShingle Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
Borgonovo,Tamara
hematological disorders
myelodysplasias
cancer cytogenetics
title_short Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
title_full Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
title_fullStr Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
title_full_unstemmed Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
title_sort Cytogenetic study of Brazilian patients with myelodysplastic syndrome (MDS)
author Borgonovo,Tamara
author_facet Borgonovo,Tamara
Ribeiro,Enilze M.S.F.
Cornélio,Déborah Afonso
Schmid-Braz,Ana Teresa
Jamur,Valderez Ravaglio
Wuicik,Lismeri
Veiga,Loraine Beatriz Acosta
Ehmke,Néria A. Maia
Pasquini,Ricardo
Cavalli,Iglenir João
author_role author
author2 Ribeiro,Enilze M.S.F.
Cornélio,Déborah Afonso
Schmid-Braz,Ana Teresa
Jamur,Valderez Ravaglio
Wuicik,Lismeri
Veiga,Loraine Beatriz Acosta
Ehmke,Néria A. Maia
Pasquini,Ricardo
Cavalli,Iglenir João
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Borgonovo,Tamara
Ribeiro,Enilze M.S.F.
Cornélio,Déborah Afonso
Schmid-Braz,Ana Teresa
Jamur,Valderez Ravaglio
Wuicik,Lismeri
Veiga,Loraine Beatriz Acosta
Ehmke,Néria A. Maia
Pasquini,Ricardo
Cavalli,Iglenir João
dc.subject.por.fl_str_mv hematological disorders
myelodysplasias
cancer cytogenetics
topic hematological disorders
myelodysplasias
cancer cytogenetics
description Bone marrow cytogenetic studies were performed on 93 patients with primary myelodysplastic syndrome (MDS) diagnosed at the Clinical Hospital of the Federal University of Paraná, Brazil. Chromosomal alterations were observed in 69% of the patients. Monosomy of chromosome 7, deletions of 7q, 5q, 12p and 20q, rearrangements of 11q23 and trisomies of chromosomes 8 and 21 were the most frequent abnormalities observed. Among adult patients the most frequent aberrations were rearrangements of 11q23 and 12p deletions. In the pediatric group, 5q deletions and monosomy of chromosome 7 were the most common alterations.
publishDate 2005
dc.date.none.fl_str_mv 2005-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500002
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572005000500002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47572005000500002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.28 n.4 2005
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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