Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina

Detalhes bibliográficos
Autor(a) principal: Kaufman,Letícia
Data de Publicação: 1998
Outros Autores: Carnese,Francisco R., Goicoechea,Alicia, Dejean,Cristina, Salzano,Francisco M., Hutz,Mara H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Genetics and Molecular Biology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000400003
Resumo: Haplotypes derived from five polymorphic restriction sites in the beta-globin gene cluster were investigated in 86 chromosomes from the Argentinian Mapuche. These results were integrated with those previously obtained for ten Brazilian Indian tribes. Eight haplotypes were identified, the most frequent being 2 (57%) and 6 (27%). The presence of haplotype 3 in 2% of the Mapuche chromosomes is probably an evidence of admixture with individuals of African ancestry. Due to the high number of haplotypes observed, heterozygosity as measured by the Gini-Simpson index was higher in the Mapuche than in Brazilian Indians. The haplotypic distribution in the Mapuche was also significantly different from those of all Brazilian tribes investigated. This heterogeneity could be at least partially explained by admixture with non-Indian populations.
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spelling Beta-globin gene cluster haplotypes in the Mapuche Indians of ArgentinaHaplotypes derived from five polymorphic restriction sites in the beta-globin gene cluster were investigated in 86 chromosomes from the Argentinian Mapuche. These results were integrated with those previously obtained for ten Brazilian Indian tribes. Eight haplotypes were identified, the most frequent being 2 (57%) and 6 (27%). The presence of haplotype 3 in 2% of the Mapuche chromosomes is probably an evidence of admixture with individuals of African ancestry. Due to the high number of haplotypes observed, heterozygosity as measured by the Gini-Simpson index was higher in the Mapuche than in Brazilian Indians. The haplotypic distribution in the Mapuche was also significantly different from those of all Brazilian tribes investigated. This heterogeneity could be at least partially explained by admixture with non-Indian populations.Sociedade Brasileira de Genética1998-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000400003Genetics and Molecular Biology v.21 n.4 1998reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47571998000400003info:eu-repo/semantics/openAccessKaufman,LetíciaCarnese,Francisco R.Goicoechea,AliciaDejean,CristinaSalzano,Francisco M.Hutz,Mara H.eng1999-03-01T00:00:00Zoai:scielo:S1415-47571998000400003Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:1999-03-01T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false
dc.title.none.fl_str_mv Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
title Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
spellingShingle Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
Kaufman,Letícia
title_short Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
title_full Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
title_fullStr Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
title_full_unstemmed Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
title_sort Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
author Kaufman,Letícia
author_facet Kaufman,Letícia
Carnese,Francisco R.
Goicoechea,Alicia
Dejean,Cristina
Salzano,Francisco M.
Hutz,Mara H.
author_role author
author2 Carnese,Francisco R.
Goicoechea,Alicia
Dejean,Cristina
Salzano,Francisco M.
Hutz,Mara H.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Kaufman,Letícia
Carnese,Francisco R.
Goicoechea,Alicia
Dejean,Cristina
Salzano,Francisco M.
Hutz,Mara H.
description Haplotypes derived from five polymorphic restriction sites in the beta-globin gene cluster were investigated in 86 chromosomes from the Argentinian Mapuche. These results were integrated with those previously obtained for ten Brazilian Indian tribes. Eight haplotypes were identified, the most frequent being 2 (57%) and 6 (27%). The presence of haplotype 3 in 2% of the Mapuche chromosomes is probably an evidence of admixture with individuals of African ancestry. Due to the high number of haplotypes observed, heterozygosity as measured by the Gini-Simpson index was higher in the Mapuche than in Brazilian Indians. The haplotypic distribution in the Mapuche was also significantly different from those of all Brazilian tribes investigated. This heterogeneity could be at least partially explained by admixture with non-Indian populations.
publishDate 1998
dc.date.none.fl_str_mv 1998-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000400003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000400003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1415-47571998000400003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Genética
publisher.none.fl_str_mv Sociedade Brasileira de Genética
dc.source.none.fl_str_mv Genetics and Molecular Biology v.21 n.4 1998
reponame:Genetics and Molecular Biology
instname:Sociedade Brasileira de Genética (SBG)
instacron:SBG
instname_str Sociedade Brasileira de Genética (SBG)
instacron_str SBG
institution SBG
reponame_str Genetics and Molecular Biology
collection Genetics and Molecular Biology
repository.name.fl_str_mv Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)
repository.mail.fl_str_mv ||editor@gmb.org.br
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