The effects of physical conditioning on the immunosenescence

• Autor(a) principal: Anjos,Márcia Cristina Gomes dos
• Data de Publicação: 2013
• Outros Autores: Passos,Luiz Fernando de Souza, Malheiro,Adriana
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Geriatrics, Gerontology and Aging (Online)
• Texto Completo: https://ggaging.com/details/168
• topic: Aging, physical fitness, immune system, immune system.

<p>The foundations elaborated and systematized in this review deal with the effects of fitness on the immune system of elderly front of immunosenescence, since currently the aging and health issues have received special attention due to the exponential increase of the elderly population in the world. This work aims to conduct a systematic literature review on the main effects of physical conditioning on the expression of cytokines and cells of the immune system of elderly people. In order to contextualize this analysis, we performed a literature search in MEDLINE, SciELO, BIREME, and LILACS. We selected studies that included the keywords in the title: immunosenescence, aging, older aldults or elderly, exercise, physical therapy or exercise therapy and its equivalent in Portuguese. The contribution of this study is to investigate whether a simple and low cost, physical activity, can be effective also in the immune system, whereas already well elucidated the benefits of regular exercise in other body systems as well as in younger populations. In general, prolonged physical activity and customized for the elderly has been identified as an important predictor of human longevity therefore affects all body systems and especially in the immune system, aiding in the regulation of immune responses by enhancing the activity of NK cells, balancing the balance of pro-inflammatory and anti-inflammatory cytokines (de acordo), orchestrating a better response to antigens, and, under a global point of view, helping to reverse or minimize the deleterious effects of aging on the immune system.</p>