Sarcopenia, bone mineral density, and vitamin D: EpiFloripa aging study 2013/2014

• Autor(a) principal: Confortin,Susana Cararo
• Data de Publicação: 2020
• Outros Autores: Ono,Lariane Mortean, Marques,Larissa Pruner, Figueiró,Thamara Hubler, Ceolin,Gilciane, Barbosa,Aline Rodrigues, d’Orsi,Eleonora
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Geriatrics, Gerontology and Aging (Online)
• Texto Completo: https://ggaging.com/details/1659
• topic: sarcopenia; osteoporosis; bone diseases, metabolic; aged.

<p><b>OBJECTIVE:</b> To verify associations between osteopenia/osteoporosis and vitamin D and sarcopenia in the older adult population of Florianópolis, Brazil.<br> <b>METHODS:</b> A cross-sectional population-based study, with 604 older adults (60 years and over). The appendicular muscle mass index (AMMI) was used to identify sarcopenia, with cutoffs of AMMI (Kg/m²) &lt; 7.26 kg/m² for men and &lt; 5.50 kg/m² for women indicating inadequate values (sarcopenia). The independent variable osteopenia/osteoporosis was measured using bone mineral density (BMD, g/cm²): T-Scores for whole body BMD, lumbar spine BMD, and femoral neck BMD, categorized as normal (BMD &gt; -1 SD) or osteopenia/osteoporosis (BMD &lt; -1 SD from the mean of the young adult reference population). Fasting serum samples were collected and assayed using the microparticle chemiluminescence (CMIA)/Liaison method. Vitamin D concentrations of &lt; 30 ng/mL were defined as hypovitaminosis. Crude and adjusted logistic regression analyses were performed.<br> <b>RESULTS:</b> Osteopenia/osteoporosis in the lumbar spine and femoral neck were associated with higher odds of sarcopenia in women and men. Osteopenia/osteoporosis in the whole body was associated with sarcopenia in women only. Vitamin D was not associated with sarcopenia in either sex.<br> <b>CONCLUSIONS:</b> Having osteopenia/osteoporosis was associated with sarcopenia in this older adult population.</p>