Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products

Detalhes bibliográficos
Autor(a) principal: Soares,Luciana Arantes
Data de Publicação: 2013
Outros Autores: Sardi,Janaína de Cássia Orlandi, Gullo,Fernanda Patrícia, Pitangui,Nayla de Souza, Scorzoni,Liliana, Leite,Fernanda Sangalli, Giannini,Maria José Soares Mendes, Almeida,Ana Marisa Fusco
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003
Resumo: Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
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spelling Anti dermatophytic therapy: prospects for the discovery of new drugs from natural productsdermatophytesfilamentous funginatural productssynthetic productMillions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.Sociedade Brasileira de Microbiologia2013-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003Brazilian Journal of Microbiology v.44 n.4 2013reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822014005000011info:eu-repo/semantics/openAccessSoares,Luciana ArantesSardi,Janaína de Cássia OrlandiGullo,Fernanda PatríciaPitangui,Nayla de SouzaScorzoni,LilianaLeite,Fernanda SangalliGiannini,Maria José Soares MendesAlmeida,Ana Marisa Fuscoeng2014-03-27T00:00:00Zoai:scielo:S1517-83822013000400003Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2014-03-27T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
title Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
spellingShingle Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
Soares,Luciana Arantes
dermatophytes
filamentous fungi
natural products
synthetic product
title_short Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
title_full Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
title_fullStr Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
title_full_unstemmed Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
title_sort Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
author Soares,Luciana Arantes
author_facet Soares,Luciana Arantes
Sardi,Janaína de Cássia Orlandi
Gullo,Fernanda Patrícia
Pitangui,Nayla de Souza
Scorzoni,Liliana
Leite,Fernanda Sangalli
Giannini,Maria José Soares Mendes
Almeida,Ana Marisa Fusco
author_role author
author2 Sardi,Janaína de Cássia Orlandi
Gullo,Fernanda Patrícia
Pitangui,Nayla de Souza
Scorzoni,Liliana
Leite,Fernanda Sangalli
Giannini,Maria José Soares Mendes
Almeida,Ana Marisa Fusco
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Soares,Luciana Arantes
Sardi,Janaína de Cássia Orlandi
Gullo,Fernanda Patrícia
Pitangui,Nayla de Souza
Scorzoni,Liliana
Leite,Fernanda Sangalli
Giannini,Maria José Soares Mendes
Almeida,Ana Marisa Fusco
dc.subject.por.fl_str_mv dermatophytes
filamentous fungi
natural products
synthetic product
topic dermatophytes
filamentous fungi
natural products
synthetic product
description Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
publishDate 2013
dc.date.none.fl_str_mv 2013-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000400003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1517-83822014005000011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.44 n.4 2013
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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