The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Microbiology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400840 |
Resumo: | ABSTRACT Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 µmol mL-1 respectively. Captan and difenoconazole were included as positive controls (MIC 16.63 and 0.02 µmol mL-1, respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. |
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The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose2-Hexylidene-3-methylbutanedioic acidAmazonAnthracnosePlant pathogenABSTRACT Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 µmol mL-1 respectively. Captan and difenoconazole were included as positive controls (MIC 16.63 and 0.02 µmol mL-1, respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease.Sociedade Brasileira de Microbiologia2018-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400840Brazilian Journal of Microbiology v.49 n.4 2018reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1016/j.bjm.2018.03.003info:eu-repo/semantics/openAccessElias,Luciana M.Fortkamp,DianaSartori,Sérgio B.Ferreira,Marília C.Gomes,Luiz H.Azevedo,João L.Montoya,Quimi V.Rodrigues,AndréFerreira,Antonio G.Lira,Simone P.eng2018-10-17T00:00:00Zoai:scielo:S1517-83822018000400840Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2018-10-17T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false |
dc.title.none.fl_str_mv |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
spellingShingle |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose Elias,Luciana M. 2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
title_short |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_full |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_fullStr |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_full_unstemmed |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
title_sort |
The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnose |
author |
Elias,Luciana M. |
author_facet |
Elias,Luciana M. Fortkamp,Diana Sartori,Sérgio B. Ferreira,Marília C. Gomes,Luiz H. Azevedo,João L. Montoya,Quimi V. Rodrigues,André Ferreira,Antonio G. Lira,Simone P. |
author_role |
author |
author2 |
Fortkamp,Diana Sartori,Sérgio B. Ferreira,Marília C. Gomes,Luiz H. Azevedo,João L. Montoya,Quimi V. Rodrigues,André Ferreira,Antonio G. Lira,Simone P. |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Elias,Luciana M. Fortkamp,Diana Sartori,Sérgio B. Ferreira,Marília C. Gomes,Luiz H. Azevedo,João L. Montoya,Quimi V. Rodrigues,André Ferreira,Antonio G. Lira,Simone P. |
dc.subject.por.fl_str_mv |
2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
topic |
2-Hexylidene-3-methylbutanedioic acid Amazon Anthracnose Plant pathogen |
description |
ABSTRACT Anthracnose is a crop disease usually caused by fungi in the genus Colletotrichum or Gloeosporium. These are considered one of the main pathogens, causing significant economic losses, such as in peppers and guarana. The current forms of control include the use of resistant cultivars, sanitary pruning and fungicides. However, even with the use of some methods of controlling these cultures, the crops are not free of anthracnose. Additionally, excessive application of fungicides increases the resistance of pathogens to agrochemicals and cause harm to human health and the environment. In order to find natural antifungal agents against guarana anthracnose, endophytic fungi were isolated from Amazon guarana. The compounds piliformic acid and cytochalasin D were isolated by chromatographic techniques from two Xylaria spp., guided by assays with Colletotrichum gloeosporioides. The isolated compounds were identified by spectrometric techniques, as NMR and mass spectrometry. This is the first report that piliformic acid and cytochalasin D have antifungal activity against C. gloeosporioides with MIC 2.92 and 2.46 µmol mL-1 respectively. Captan and difenoconazole were included as positive controls (MIC 16.63 and 0.02 µmol mL-1, respectively). Thus, Xylaria species presented a biotechnological potential and production of different active compounds which might be promising against anthracnose disease. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400840 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000400840 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.bjm.2018.03.003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Microbiology v.49 n.4 2018 reponame:Brazilian Journal of Microbiology instname:Sociedade Brasileira de Microbiologia (SBM) instacron:SBM |
instname_str |
Sociedade Brasileira de Microbiologia (SBM) |
instacron_str |
SBM |
institution |
SBM |
reponame_str |
Brazilian Journal of Microbiology |
collection |
Brazilian Journal of Microbiology |
repository.name.fl_str_mv |
Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM) |
repository.mail.fl_str_mv |
bjm@sbmicrobiologia.org.br||mbmartin@usp.br |
_version_ |
1752122209789280256 |