Antifungal activity of lectins against yeast of vaginal secretion
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Microbiology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200042 |
Resumo: | Lectins are carbohydrate-binding proteins of non-imune origin. This group of proteins is distributed widely in nature and they have been found in viruses, microorganisms, plants and animals. Lectins of plants have been isolated and characterized according to their chemical, physical-chemical, structural and biological properties. Among their biological activities, we can stress its fungicidal action. It has been previously described the effect of the lectins Dviol, DRL, ConBr and LSL obtained from the seeds of leguminous plants on the growth of yeasts isolated from vaginal secretions. In the present work the experiments were carried out in microtiter plates and the results interpreted by both methods: visual observations and a microplate reader at 530nm. The lectin concentrations varied from 0.5 to 256µg/mL, and the inoculum was established between 65-70% of trammitance. All yeast samples isolated from vaginal secretion were evaluated taxonomically, where were observed macroscopic and microscopic characteristics to each species. The LSL lectin did not demonstrate any antifungal activity to any isolate studied. The other lectins DRL, ConBr and DvioL, showed antifungal potential against yeast isolated from vaginal secretion. These findings offering offer a promising field of investigation to develop new therapeutic strategies against vaginal yeast infections, collaborating to improve women's health. |
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Brazilian Journal of Microbiology |
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Antifungal activity of lectins against yeast of vaginal secretionYeastsensitivitylectinsLectins are carbohydrate-binding proteins of non-imune origin. This group of proteins is distributed widely in nature and they have been found in viruses, microorganisms, plants and animals. Lectins of plants have been isolated and characterized according to their chemical, physical-chemical, structural and biological properties. Among their biological activities, we can stress its fungicidal action. It has been previously described the effect of the lectins Dviol, DRL, ConBr and LSL obtained from the seeds of leguminous plants on the growth of yeasts isolated from vaginal secretions. In the present work the experiments were carried out in microtiter plates and the results interpreted by both methods: visual observations and a microplate reader at 530nm. The lectin concentrations varied from 0.5 to 256µg/mL, and the inoculum was established between 65-70% of trammitance. All yeast samples isolated from vaginal secretion were evaluated taxonomically, where were observed macroscopic and microscopic characteristics to each species. The LSL lectin did not demonstrate any antifungal activity to any isolate studied. The other lectins DRL, ConBr and DvioL, showed antifungal potential against yeast isolated from vaginal secretion. These findings offering offer a promising field of investigation to develop new therapeutic strategies against vaginal yeast infections, collaborating to improve women's health.Sociedade Brasileira de Microbiologia2012-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200042Brazilian Journal of Microbiology v.43 n.2 2012reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1590/S1517-83822012000200042info:eu-repo/semantics/openAccessGomes,Bruno SeveroSiqueira,Ana Beatriz SoteroMaia,Rita de Cássia CarvalhoGiampaoli,VivianaTeixeira,Edson HolandaArruda,Francisco Vassiliepe SousaNascimento,Kyria Santiago doLima,Adriana Nunes deSouza-Motta,Cristina MariaCavada,Benildo SousaPorto,Ana Lúcia Figueiredoeng2012-08-07T00:00:00Zoai:scielo:S1517-83822012000200042Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2012-08-07T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false |
dc.title.none.fl_str_mv |
Antifungal activity of lectins against yeast of vaginal secretion |
title |
Antifungal activity of lectins against yeast of vaginal secretion |
spellingShingle |
Antifungal activity of lectins against yeast of vaginal secretion Gomes,Bruno Severo Yeast sensitivity lectins |
title_short |
Antifungal activity of lectins against yeast of vaginal secretion |
title_full |
Antifungal activity of lectins against yeast of vaginal secretion |
title_fullStr |
Antifungal activity of lectins against yeast of vaginal secretion |
title_full_unstemmed |
Antifungal activity of lectins against yeast of vaginal secretion |
title_sort |
Antifungal activity of lectins against yeast of vaginal secretion |
author |
Gomes,Bruno Severo |
author_facet |
Gomes,Bruno Severo Siqueira,Ana Beatriz Sotero Maia,Rita de Cássia Carvalho Giampaoli,Viviana Teixeira,Edson Holanda Arruda,Francisco Vassiliepe Sousa Nascimento,Kyria Santiago do Lima,Adriana Nunes de Souza-Motta,Cristina Maria Cavada,Benildo Sousa Porto,Ana Lúcia Figueiredo |
author_role |
author |
author2 |
Siqueira,Ana Beatriz Sotero Maia,Rita de Cássia Carvalho Giampaoli,Viviana Teixeira,Edson Holanda Arruda,Francisco Vassiliepe Sousa Nascimento,Kyria Santiago do Lima,Adriana Nunes de Souza-Motta,Cristina Maria Cavada,Benildo Sousa Porto,Ana Lúcia Figueiredo |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Gomes,Bruno Severo Siqueira,Ana Beatriz Sotero Maia,Rita de Cássia Carvalho Giampaoli,Viviana Teixeira,Edson Holanda Arruda,Francisco Vassiliepe Sousa Nascimento,Kyria Santiago do Lima,Adriana Nunes de Souza-Motta,Cristina Maria Cavada,Benildo Sousa Porto,Ana Lúcia Figueiredo |
dc.subject.por.fl_str_mv |
Yeast sensitivity lectins |
topic |
Yeast sensitivity lectins |
description |
Lectins are carbohydrate-binding proteins of non-imune origin. This group of proteins is distributed widely in nature and they have been found in viruses, microorganisms, plants and animals. Lectins of plants have been isolated and characterized according to their chemical, physical-chemical, structural and biological properties. Among their biological activities, we can stress its fungicidal action. It has been previously described the effect of the lectins Dviol, DRL, ConBr and LSL obtained from the seeds of leguminous plants on the growth of yeasts isolated from vaginal secretions. In the present work the experiments were carried out in microtiter plates and the results interpreted by both methods: visual observations and a microplate reader at 530nm. The lectin concentrations varied from 0.5 to 256µg/mL, and the inoculum was established between 65-70% of trammitance. All yeast samples isolated from vaginal secretion were evaluated taxonomically, where were observed macroscopic and microscopic characteristics to each species. The LSL lectin did not demonstrate any antifungal activity to any isolate studied. The other lectins DRL, ConBr and DvioL, showed antifungal potential against yeast isolated from vaginal secretion. These findings offering offer a promising field of investigation to develop new therapeutic strategies against vaginal yeast infections, collaborating to improve women's health. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200042 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200042 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1517-83822012000200042 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Microbiologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Microbiology v.43 n.2 2012 reponame:Brazilian Journal of Microbiology instname:Sociedade Brasileira de Microbiologia (SBM) instacron:SBM |
instname_str |
Sociedade Brasileira de Microbiologia (SBM) |
instacron_str |
SBM |
institution |
SBM |
reponame_str |
Brazilian Journal of Microbiology |
collection |
Brazilian Journal of Microbiology |
repository.name.fl_str_mv |
Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM) |
repository.mail.fl_str_mv |
bjm@sbmicrobiologia.org.br||mbmartin@usp.br |
_version_ |
1752122204652306432 |