Histophilus somni-associated syndromes in sheep from Southern Brazil

Detalhes bibliográficos
Autor(a) principal: Headley,Selwyn A.
Data de Publicação: 2018
Outros Autores: Pereira,Alfredo H.T., Balbo,Luciana C., Santia,Giovana W. Di, Bracarense,Ana P.F.R.L., Cunha Filho,Luiz F.C., Schade,Jackson, Okano,Werner, Pereira,Priscilla F.V., Morotti,Fábio, Preto-Giordano,Lucienne G., Marcasso,Rogério A., Alfieri,Alice F., Lisbôa,Júlio A.N., Alfieri,Amauri A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300591
Resumo: Abstract Histophilus somni is a Gram-negative bacterium that is associated with a disease complex (termed histophilosis) that can produce several clinical syndromes predominantly in cattle, but also in sheep. Histophilosis is well described in North America, Canada, and in some European countries. In Brazil, histophilosis has been described in cattle with respiratory, reproductive, and systemic disease, with only one case described in sheep. This report describes the occurrence of Histophilus somni-associated disease in sheep from Southern Brazil. Eight sheep with different clinical manifestations from five farms were investigated by a combination of pathological and molecular diagnostic methods to identify additional cases of histophilosis in sheep from Brazil. The principal pathological lesions were thrombotic meningoencephalitis, fibrinous bronchopneumonia, pulmonary abscesses, and necrotizing myocarditis. The main clinical syndromes associated with H. somni were thrombotic meningoencephalitis (n = 4), septicemia (n = 4), bronchopneumonia (n = 4), and myocarditis (n = 3). H. somni DNA was amplified from multiple tissues of all sheep with clinical syndromes of histophilosis; sequencing confirmed the PCR results. Further, PCR assays to detect Pasteurella multocida and Mannheimia haemolytica were negative. These findings confirmed the participation of H. somni in the clinical syndromes investigated during this study, and adds to the previous report of histophilosis in sheep from Brazil.
id SBM-1_f93025b0cf3c65be842723ccca264e77
oai_identifier_str oai:scielo:S1517-83822018000300591
network_acronym_str SBM-1
network_name_str Brazilian Journal of Microbiology
repository_id_str
spelling Histophilus somni-associated syndromes in sheep from Southern BrazilHistophilosisMolecular testingBronchopneumoniaMyocarditisThrombotic meningoencephalitisAbstract Histophilus somni is a Gram-negative bacterium that is associated with a disease complex (termed histophilosis) that can produce several clinical syndromes predominantly in cattle, but also in sheep. Histophilosis is well described in North America, Canada, and in some European countries. In Brazil, histophilosis has been described in cattle with respiratory, reproductive, and systemic disease, with only one case described in sheep. This report describes the occurrence of Histophilus somni-associated disease in sheep from Southern Brazil. Eight sheep with different clinical manifestations from five farms were investigated by a combination of pathological and molecular diagnostic methods to identify additional cases of histophilosis in sheep from Brazil. The principal pathological lesions were thrombotic meningoencephalitis, fibrinous bronchopneumonia, pulmonary abscesses, and necrotizing myocarditis. The main clinical syndromes associated with H. somni were thrombotic meningoencephalitis (n = 4), septicemia (n = 4), bronchopneumonia (n = 4), and myocarditis (n = 3). H. somni DNA was amplified from multiple tissues of all sheep with clinical syndromes of histophilosis; sequencing confirmed the PCR results. Further, PCR assays to detect Pasteurella multocida and Mannheimia haemolytica were negative. These findings confirmed the participation of H. somni in the clinical syndromes investigated during this study, and adds to the previous report of histophilosis in sheep from Brazil.Sociedade Brasileira de Microbiologia2018-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300591Brazilian Journal of Microbiology v.49 n.3 2018reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1016/j.bjm.2017.12.008info:eu-repo/semantics/openAccessHeadley,Selwyn A.Pereira,Alfredo H.T.Balbo,Luciana C.Santia,Giovana W. DiBracarense,Ana P.F.R.L.Cunha Filho,Luiz F.C.Schade,JacksonOkano,WernerPereira,Priscilla F.V.Morotti,FábioPreto-Giordano,Lucienne G.Marcasso,Rogério A.Alfieri,Alice F.Lisbôa,Júlio A.N.Alfieri,Amauri A.eng2018-08-03T00:00:00Zoai:scielo:S1517-83822018000300591Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2018-08-03T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Histophilus somni-associated syndromes in sheep from Southern Brazil
title Histophilus somni-associated syndromes in sheep from Southern Brazil
spellingShingle Histophilus somni-associated syndromes in sheep from Southern Brazil
Headley,Selwyn A.
Histophilosis
Molecular testing
Bronchopneumonia
Myocarditis
Thrombotic meningoencephalitis
title_short Histophilus somni-associated syndromes in sheep from Southern Brazil
title_full Histophilus somni-associated syndromes in sheep from Southern Brazil
title_fullStr Histophilus somni-associated syndromes in sheep from Southern Brazil
title_full_unstemmed Histophilus somni-associated syndromes in sheep from Southern Brazil
title_sort Histophilus somni-associated syndromes in sheep from Southern Brazil
author Headley,Selwyn A.
author_facet Headley,Selwyn A.
Pereira,Alfredo H.T.
Balbo,Luciana C.
Santia,Giovana W. Di
Bracarense,Ana P.F.R.L.
Cunha Filho,Luiz F.C.
Schade,Jackson
Okano,Werner
Pereira,Priscilla F.V.
Morotti,Fábio
Preto-Giordano,Lucienne G.
Marcasso,Rogério A.
Alfieri,Alice F.
Lisbôa,Júlio A.N.
Alfieri,Amauri A.
author_role author
author2 Pereira,Alfredo H.T.
Balbo,Luciana C.
Santia,Giovana W. Di
Bracarense,Ana P.F.R.L.
Cunha Filho,Luiz F.C.
Schade,Jackson
Okano,Werner
Pereira,Priscilla F.V.
Morotti,Fábio
Preto-Giordano,Lucienne G.
Marcasso,Rogério A.
Alfieri,Alice F.
Lisbôa,Júlio A.N.
Alfieri,Amauri A.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Headley,Selwyn A.
Pereira,Alfredo H.T.
Balbo,Luciana C.
Santia,Giovana W. Di
Bracarense,Ana P.F.R.L.
Cunha Filho,Luiz F.C.
Schade,Jackson
Okano,Werner
Pereira,Priscilla F.V.
Morotti,Fábio
Preto-Giordano,Lucienne G.
Marcasso,Rogério A.
Alfieri,Alice F.
Lisbôa,Júlio A.N.
Alfieri,Amauri A.
dc.subject.por.fl_str_mv Histophilosis
Molecular testing
Bronchopneumonia
Myocarditis
Thrombotic meningoencephalitis
topic Histophilosis
Molecular testing
Bronchopneumonia
Myocarditis
Thrombotic meningoencephalitis
description Abstract Histophilus somni is a Gram-negative bacterium that is associated with a disease complex (termed histophilosis) that can produce several clinical syndromes predominantly in cattle, but also in sheep. Histophilosis is well described in North America, Canada, and in some European countries. In Brazil, histophilosis has been described in cattle with respiratory, reproductive, and systemic disease, with only one case described in sheep. This report describes the occurrence of Histophilus somni-associated disease in sheep from Southern Brazil. Eight sheep with different clinical manifestations from five farms were investigated by a combination of pathological and molecular diagnostic methods to identify additional cases of histophilosis in sheep from Brazil. The principal pathological lesions were thrombotic meningoencephalitis, fibrinous bronchopneumonia, pulmonary abscesses, and necrotizing myocarditis. The main clinical syndromes associated with H. somni were thrombotic meningoencephalitis (n = 4), septicemia (n = 4), bronchopneumonia (n = 4), and myocarditis (n = 3). H. somni DNA was amplified from multiple tissues of all sheep with clinical syndromes of histophilosis; sequencing confirmed the PCR results. Further, PCR assays to detect Pasteurella multocida and Mannheimia haemolytica were negative. These findings confirmed the participation of H. somni in the clinical syndromes investigated during this study, and adds to the previous report of histophilosis in sheep from Brazil.
publishDate 2018
dc.date.none.fl_str_mv 2018-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300591
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000300591
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjm.2017.12.008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.49 n.3 2018
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
_version_ 1752122209719025664