Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin

Detalhes bibliográficos
Autor(a) principal: Alves,Guilherme Guerra
Data de Publicação: 2017
Outros Autores: Machado-de-Ávila,Ricardo Andrez, Chávez-Olórtegui,Carlos Delfin, Silva,Rodrigo Otávio Silveira, Lobato,Francisco Carlos Faria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Microbiology
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300570
Resumo: Abstract The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.
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spelling Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxinEpsilonToxinEnterotoxemiaEpitopeMappingAbstract The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.Sociedade Brasileira de Microbiologia2017-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300570Brazilian Journal of Microbiology v.48 n.3 2017reponame:Brazilian Journal of Microbiologyinstname:Sociedade Brasileira de Microbiologia (SBM)instacron:SBM10.1016/j.bjm.2016.10.023info:eu-repo/semantics/openAccessAlves,Guilherme GuerraMachado-de-Ávila,Ricardo AndrezChávez-Olórtegui,Carlos DelfinSilva,Rodrigo Otávio SilveiraLobato,Francisco Carlos Fariaeng2017-07-31T00:00:00Zoai:scielo:S1517-83822017000300570Revistahttps://www.scielo.br/j/bjm/ONGhttps://old.scielo.br/oai/scielo-oai.phpbjm@sbmicrobiologia.org.br||mbmartin@usp.br1678-44051517-8382opendoar:2017-07-31T00:00Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)false
dc.title.none.fl_str_mv Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
spellingShingle Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
Alves,Guilherme Guerra
Epsilon
Toxin
Enterotoxemia
Epitope
Mapping
title_short Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_full Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_fullStr Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_full_unstemmed Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
title_sort Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
author Alves,Guilherme Guerra
author_facet Alves,Guilherme Guerra
Machado-de-Ávila,Ricardo Andrez
Chávez-Olórtegui,Carlos Delfin
Silva,Rodrigo Otávio Silveira
Lobato,Francisco Carlos Faria
author_role author
author2 Machado-de-Ávila,Ricardo Andrez
Chávez-Olórtegui,Carlos Delfin
Silva,Rodrigo Otávio Silveira
Lobato,Francisco Carlos Faria
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Alves,Guilherme Guerra
Machado-de-Ávila,Ricardo Andrez
Chávez-Olórtegui,Carlos Delfin
Silva,Rodrigo Otávio Silveira
Lobato,Francisco Carlos Faria
dc.subject.por.fl_str_mv Epsilon
Toxin
Enterotoxemia
Epitope
Mapping
topic Epsilon
Toxin
Enterotoxemia
Epitope
Mapping
description Abstract The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.
publishDate 2017
dc.date.none.fl_str_mv 2017-07-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300570
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300570
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.bjm.2016.10.023
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
publisher.none.fl_str_mv Sociedade Brasileira de Microbiologia
dc.source.none.fl_str_mv Brazilian Journal of Microbiology v.48 n.3 2017
reponame:Brazilian Journal of Microbiology
instname:Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
instname_str Sociedade Brasileira de Microbiologia (SBM)
instacron_str SBM
institution SBM
reponame_str Brazilian Journal of Microbiology
collection Brazilian Journal of Microbiology
repository.name.fl_str_mv Brazilian Journal of Microbiology - Sociedade Brasileira de Microbiologia (SBM)
repository.mail.fl_str_mv bjm@sbmicrobiologia.org.br||mbmartin@usp.br
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