Community urinary tract infections: prevalence and antimicrobial susceptibility in Florianópolis

• Autor(a) principal: Alves, Débora Monteiro dos Santos
• Data de Publicação: 2016
• Outros Autores: Edelweiss, Marcos Krahe, Botelho, Lúcio José
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Brasileira de Medicina de Família e Comunidade (Online)
• Texto Completo: https://www.rbmfc.org.br/rbmfc/article/view/1187
• topic: Urinary Tract Infections. Enterobacteriaceae. infections Microbial .Sensitivity Tests Drug Resistance; Microbial; Infecciones Urinarias. Infecciones por Enterobacteriaceae. Pruebas de Sensibilidad Microbiana. Farmacorresistencia Microbiana.; Infecções Urinárias. Infecções por Enterobacteriaceae. Antibiograma. Resistência Microbiana a Medicamentos.; Infecções urinárias

Objectives: Determine the isolation frequency of uropathogens and evaluate the antimicrobial susceptibility profile in vitro of the bacteria isolated from urine cultures of outpatients treated in Florianópolis in 2014, correlating these data with gender and age of the patient. Methods: This is an observational, descriptive cross-sectional study which included positive urine cultures of outpatients performed in a single laboratory using the same methodology. Descriptive statistic analyses and tests of association between categorical variables: gender, age, etiologic agent and antimicrobial susceptibility were performed. Results: Positive urine cultures were registered in 1035 patients, of which 89.66% are female. Gram-negative pathogens were more isolated, especially E. coli (77.10%), the main causal agent. P. mirabilis was significantly more prevalent in males and the main microorganism isolated in urine cultures of 1-5 years-old children. E. coli was significantly more prevalent in females and presented the wider profile of resistance. This study showed statistically significant differences in resistance to fluoroquinolones between genders, with higher resistance prevalence in men and between age groups, with higher resistance among the elderly. Conclusions: Age and gender are determinant variables in the isolation frequency of uropathogens and in the prevalence of antimicrobial susceptibility; and the most prevalent microorganisms have not satisfactorily respond to the part of antimicrobials used. It is essential that the physician use such information at the time of therapeutic decision and respect the rational use of antimicrobials, especially those of broad spectrum as fluoroquinolones.