Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients

Detalhes bibliográficos
Autor(a) principal: Galván-Ramírez,Maria de la Luz
Data de Publicação: 1998
Outros Autores: Guillén-Vargas,Cecilia, Saavedra-Durán,Rafael, Islas-Rodríguez,Alfonso
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004
Resumo: Some proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis.
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spelling Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patientsToxoplasmosisAcuteChronicAntigenToxoplasma gondiiSome proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis.Sociedade Brasileira de Medicina Tropical - SBMT1998-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004Revista da Sociedade Brasileira de Medicina Tropical v.31 n.3 1998reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86821998000300004info:eu-repo/semantics/openAccessGalván-Ramírez,Maria de la LuzGuillén-Vargas,CeciliaSaavedra-Durán,RafaelIslas-Rodríguez,Alfonsoeng2000-06-13T00:00:00Zoai:scielo:S0037-86821998000300004Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2000-06-13T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
title Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
spellingShingle Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
Galván-Ramírez,Maria de la Luz
Toxoplasmosis
Acute
Chronic
Antigen
Toxoplasma gondii
title_short Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
title_full Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
title_fullStr Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
title_full_unstemmed Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
title_sort Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
author Galván-Ramírez,Maria de la Luz
author_facet Galván-Ramírez,Maria de la Luz
Guillén-Vargas,Cecilia
Saavedra-Durán,Rafael
Islas-Rodríguez,Alfonso
author_role author
author2 Guillén-Vargas,Cecilia
Saavedra-Durán,Rafael
Islas-Rodríguez,Alfonso
author2_role author
author
author
dc.contributor.author.fl_str_mv Galván-Ramírez,Maria de la Luz
Guillén-Vargas,Cecilia
Saavedra-Durán,Rafael
Islas-Rodríguez,Alfonso
dc.subject.por.fl_str_mv Toxoplasmosis
Acute
Chronic
Antigen
Toxoplasma gondii
topic Toxoplasmosis
Acute
Chronic
Antigen
Toxoplasma gondii
description Some proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis.
publishDate 1998
dc.date.none.fl_str_mv 1998-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86821998000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.31 n.3 1998
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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