Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Sociedade Brasileira de Medicina Tropical |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004 |
Resumo: | Some proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis. |
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Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patientsToxoplasmosisAcuteChronicAntigenToxoplasma gondiiSome proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis.Sociedade Brasileira de Medicina Tropical - SBMT1998-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004Revista da Sociedade Brasileira de Medicina Tropical v.31 n.3 1998reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86821998000300004info:eu-repo/semantics/openAccessGalván-Ramírez,Maria de la LuzGuillén-Vargas,CeciliaSaavedra-Durán,RafaelIslas-Rodríguez,Alfonsoeng2000-06-13T00:00:00Zoai:scielo:S0037-86821998000300004Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2000-06-13T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
title |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
spellingShingle |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients Galván-Ramírez,Maria de la Luz Toxoplasmosis Acute Chronic Antigen Toxoplasma gondii |
title_short |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
title_full |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
title_fullStr |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
title_full_unstemmed |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
title_sort |
Analysis of Toxoplasma gondii antigens with sera from toxoplasmosis patients |
author |
Galván-Ramírez,Maria de la Luz |
author_facet |
Galván-Ramírez,Maria de la Luz Guillén-Vargas,Cecilia Saavedra-Durán,Rafael Islas-Rodríguez,Alfonso |
author_role |
author |
author2 |
Guillén-Vargas,Cecilia Saavedra-Durán,Rafael Islas-Rodríguez,Alfonso |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Galván-Ramírez,Maria de la Luz Guillén-Vargas,Cecilia Saavedra-Durán,Rafael Islas-Rodríguez,Alfonso |
dc.subject.por.fl_str_mv |
Toxoplasmosis Acute Chronic Antigen Toxoplasma gondii |
topic |
Toxoplasmosis Acute Chronic Antigen Toxoplasma gondii |
description |
Some proteins of the Toxoplasma gondii are recognized by IgG, IgM and IgA antibodies in patients with acute and chronic toxoplasmosis, depending on the strain and stage of the Toxoplasma. Sixty-nine sera from immunocompetent individuals were studied through the Western-Blot Test: 20 has an acute infection, 29 has a chronic toxoplasmosis infection and 20 were healthy (seronegatives). The protein analysis revealed by IgG and IgM antibodies were performed through the Immunoplot method in order to know their recognition frequency (f) and be valued as infection markers. In the acute phase, the IgM antibodies showed a recognition frequency (f = 0.60) for the 60kDa protein, and in the chronic phase the IgG antibodies showed a recognition frequency (f = 0.68) for the 12kDa protein. Seronegatives revealed no type of band. The protein of 12kDa can be a diagnostic marker of the chronic phase while protein 60kDa of the acute phase of toxoplasmosis. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821998000300004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86821998000300004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.31 n.3 1998 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
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1752122150369624064 |