Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens

Detalhes bibliográficos
Autor(a) principal: Pereira,Valéria R.A.
Data de Publicação: 2000
Outros Autores: Nakazawa,Mineo, Furtado,Veridiana C., Abath,Frederico G.C., Gomes,Yara M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400006
Resumo: The polypeptides of 46 and 58kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respectively when Tc 46 was used. When Tc 58 was used the sensitivity and specificity were 100% [CI 95%: 89.6-100%] and 90.2% [CI 95%: 75.9-96.8%], respectively.
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spelling Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigensT. cruziInsoluble antigensImmunodiagnosisChagas' diseaseThe polypeptides of 46 and 58kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respectively when Tc 46 was used. When Tc 58 was used the sensitivity and specificity were 100% [CI 95%: 89.6-100%] and 90.2% [CI 95%: 75.9-96.8%], respectively.Sociedade Brasileira de Medicina Tropical - SBMT2000-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400006Revista da Sociedade Brasileira de Medicina Tropical v.33 n.4 2000reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822000000400006info:eu-repo/semantics/openAccessPereira,Valéria R.A.Nakazawa,MineoFurtado,Veridiana C.Abath,Frederico G.C.Gomes,Yara M.eng2000-08-24T00:00:00Zoai:scielo:S0037-86822000000400006Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2000-08-24T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
title Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
spellingShingle Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
Pereira,Valéria R.A.
T. cruzi
Insoluble antigens
Immunodiagnosis
Chagas' disease
title_short Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
title_full Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
title_fullStr Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
title_full_unstemmed Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
title_sort Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens
author Pereira,Valéria R.A.
author_facet Pereira,Valéria R.A.
Nakazawa,Mineo
Furtado,Veridiana C.
Abath,Frederico G.C.
Gomes,Yara M.
author_role author
author2 Nakazawa,Mineo
Furtado,Veridiana C.
Abath,Frederico G.C.
Gomes,Yara M.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Valéria R.A.
Nakazawa,Mineo
Furtado,Veridiana C.
Abath,Frederico G.C.
Gomes,Yara M.
dc.subject.por.fl_str_mv T. cruzi
Insoluble antigens
Immunodiagnosis
Chagas' disease
topic T. cruzi
Insoluble antigens
Immunodiagnosis
Chagas' disease
description The polypeptides of 46 and 58kDa were recognized in different T. cruzi strains (Y, WSL and Colombiana) by serum of all chagasic patients studied. These polypeptides were isolated from T. cruzi Y strain and used in ELISA. The sensitivity and specificity were 97.6% [CI 95%: 86-100%] and 100% [CI 95%: 89.3-100%], respectively when Tc 46 was used. When Tc 58 was used the sensitivity and specificity were 100% [CI 95%: 89.6-100%] and 90.2% [CI 95%: 75.9-96.8%], respectively.
publishDate 2000
dc.date.none.fl_str_mv 2000-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822000000400006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86822000000400006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.33 n.4 2000
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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