RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP

Detalhes bibliográficos
Autor(a) principal: Levin, M. J.
Data de Publicação: 1991
Outros Autores: Silveira, J. Franco da [UNIFESP], Frasch, ACC, Camargo, M. E., Lafon, S., Degrave, W. M., Rangelaldao, R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.x
http://repositorio.unifesp.br/handle/11600/25230
Resumo: A workshop organized by the Ibero-American Project of Biotechnology evaluated the diagnostic potential of several cloned Trypanosoma cruzi recombinant antigens for Chagas' disease serodiagnosis. A set of recombinants, Antigen 2, Antigen 13, SAPA, H49, A13, JL5, JL7, JL8, JL9, and RA1 provided by three different South American laboratories were probed with a panel of 236 South American serum samples. Antigens JL7, H49, Antigen 2, and A13 scored as the best diagnostic recombinant reagents. the results suggested that the main advantage of using cloned peptides for chronic Chagas' disease diagnosis resided in their highly specific immunoreactive properties.
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spelling RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOPTRYPANOSOMA-CRUZIDIAGNOSISCHAGAS DISEASETRYPANOSOMA-CRUZI RECOMBINANT ANTIGENSIMMUNOASSAYA workshop organized by the Ibero-American Project of Biotechnology evaluated the diagnostic potential of several cloned Trypanosoma cruzi recombinant antigens for Chagas' disease serodiagnosis. A set of recombinants, Antigen 2, Antigen 13, SAPA, H49, A13, JL5, JL7, JL8, JL9, and RA1 provided by three different South American laboratories were probed with a panel of 236 South American serum samples. Antigens JL7, H49, Antigen 2, and A13 scored as the best diagnostic recombinant reagents. the results suggested that the main advantage of using cloned peptides for chronic Chagas' disease diagnosis resided in their highly specific immunoreactive properties.LAB FLEURY, São Paulo, BRAZILESCOLA PAULISTA MED SCH, DISCIPLINA PARASITOL, BR-04023 São Paulo, BRAZILFDN CAMPOMAR, INST INVEST BIOQUIM, BUENOS AIRES, ARGENTINAFDN OSWALDO CRUZ, DEPT BIOL MOLEC, RIO de JANEIRO, BRAZILUNIV SIMON BOLIVAR, CARACAS, VENEZUELAESCOLA PAULISTA MED SCH, DISCIPLINA PARASITOL, BR-04023 São Paulo, BRAZILWeb of ScienceElsevier B.V.LAB FLEURYUniversidade Federal de São Paulo (UNIFESP)FDN CAMPOMARFDN OSWALDO CRUZUNIV SIMON BOLIVARLevin, M. J.Silveira, J. Franco da [UNIFESP]Frasch, ACCCamargo, M. E.Lafon, S.Degrave, W. M.Rangelaldao, R.2016-01-24T11:40:05Z2016-01-24T11:40:05Z1991-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion11-19http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.xFems Microbiology Immunology. Amsterdam: Elsevier B.V., v. 89, n. 1, p. 11-19, 1991.10.1111/j.1574-6968.1991.tb04965.x0920-8534http://repositorio.unifesp.br/handle/11600/25230WOS:A1991GZ12200002engFems Microbiology Immunologyinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2023-03-27T08:53:24Zoai:repositorio.unifesp.br/:11600/25230Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652023-03-27T08:53:24Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
title RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
spellingShingle RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
Levin, M. J.
TRYPANOSOMA-CRUZI
DIAGNOSIS
CHAGAS DISEASE
TRYPANOSOMA-CRUZI RECOMBINANT ANTIGENS
IMMUNOASSAY
title_short RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
title_full RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
title_fullStr RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
title_full_unstemmed RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
title_sort RECOMBINANT TRYPANOSOMA-CRUZI ANTIGENS and CHAGAS-DISEASE DIAGNOSIS - ANALYSIS of A WORKSHOP
author Levin, M. J.
author_facet Levin, M. J.
Silveira, J. Franco da [UNIFESP]
Frasch, ACC
Camargo, M. E.
Lafon, S.
Degrave, W. M.
Rangelaldao, R.
author_role author
author2 Silveira, J. Franco da [UNIFESP]
Frasch, ACC
Camargo, M. E.
Lafon, S.
Degrave, W. M.
Rangelaldao, R.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv LAB FLEURY
Universidade Federal de São Paulo (UNIFESP)
FDN CAMPOMAR
FDN OSWALDO CRUZ
UNIV SIMON BOLIVAR
dc.contributor.author.fl_str_mv Levin, M. J.
Silveira, J. Franco da [UNIFESP]
Frasch, ACC
Camargo, M. E.
Lafon, S.
Degrave, W. M.
Rangelaldao, R.
dc.subject.por.fl_str_mv TRYPANOSOMA-CRUZI
DIAGNOSIS
CHAGAS DISEASE
TRYPANOSOMA-CRUZI RECOMBINANT ANTIGENS
IMMUNOASSAY
topic TRYPANOSOMA-CRUZI
DIAGNOSIS
CHAGAS DISEASE
TRYPANOSOMA-CRUZI RECOMBINANT ANTIGENS
IMMUNOASSAY
description A workshop organized by the Ibero-American Project of Biotechnology evaluated the diagnostic potential of several cloned Trypanosoma cruzi recombinant antigens for Chagas' disease serodiagnosis. A set of recombinants, Antigen 2, Antigen 13, SAPA, H49, A13, JL5, JL7, JL8, JL9, and RA1 provided by three different South American laboratories were probed with a panel of 236 South American serum samples. Antigens JL7, H49, Antigen 2, and A13 scored as the best diagnostic recombinant reagents. the results suggested that the main advantage of using cloned peptides for chronic Chagas' disease diagnosis resided in their highly specific immunoreactive properties.
publishDate 1991
dc.date.none.fl_str_mv 1991-12-01
2016-01-24T11:40:05Z
2016-01-24T11:40:05Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.x
Fems Microbiology Immunology. Amsterdam: Elsevier B.V., v. 89, n. 1, p. 11-19, 1991.
10.1111/j.1574-6968.1991.tb04965.x
0920-8534
http://repositorio.unifesp.br/handle/11600/25230
WOS:A1991GZ12200002
url http://dx.doi.org/10.1111/j.1574-6968.1991.tb04965.x
http://repositorio.unifesp.br/handle/11600/25230
identifier_str_mv Fems Microbiology Immunology. Amsterdam: Elsevier B.V., v. 89, n. 1, p. 11-19, 1991.
10.1111/j.1574-6968.1991.tb04965.x
0920-8534
WOS:A1991GZ12200002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fems Microbiology Immunology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv 11-19
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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