Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report

Detalhes bibliográficos
Autor(a) principal: Ferreira Terceiro,Benivaldo Ramos
Data de Publicação: 2019
Outros Autores: Torraca,Tania Salgado de Souza, Braga,Frederico Pereira Bom, Martins,Ana Cristina da Costa, Brahim,Lucia Regina, Saheki,Mauricio Naoto, Miranda,Luciana de Freitas Campos, Schubach,Armando de Oliveira, Valete-Rosalino,Cláudia Maria
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100700
Resumo: Abstract In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate. We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring.
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spelling Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case ReportMucosal leishmaniasisTherapyPentamidine isethionateAbstract In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate. We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring.Sociedade Brasileira de Medicina Tropical - SBMT2019-01-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100700Revista da Sociedade Brasileira de Medicina Tropical v.52 2019reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/0037-8682-0236-2018info:eu-repo/semantics/openAccessFerreira Terceiro,Benivaldo RamosTorraca,Tania Salgado de SouzaBraga,Frederico Pereira BomMartins,Ana Cristina da CostaBrahim,Lucia ReginaSaheki,Mauricio NaotoMiranda,Luciana de Freitas CamposSchubach,Armando de OliveiraValete-Rosalino,Cláudia Mariaeng2019-01-23T00:00:00Zoai:scielo:S0037-86822019000100700Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2019-01-23T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
title Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
spellingShingle Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
Ferreira Terceiro,Benivaldo Ramos
Mucosal leishmaniasis
Therapy
Pentamidine isethionate
title_short Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
title_full Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
title_fullStr Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
title_full_unstemmed Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
title_sort Good response to pentamidine isethionate in a case of Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis that was difficult to treat: Case Report
author Ferreira Terceiro,Benivaldo Ramos
author_facet Ferreira Terceiro,Benivaldo Ramos
Torraca,Tania Salgado de Souza
Braga,Frederico Pereira Bom
Martins,Ana Cristina da Costa
Brahim,Lucia Regina
Saheki,Mauricio Naoto
Miranda,Luciana de Freitas Campos
Schubach,Armando de Oliveira
Valete-Rosalino,Cláudia Maria
author_role author
author2 Torraca,Tania Salgado de Souza
Braga,Frederico Pereira Bom
Martins,Ana Cristina da Costa
Brahim,Lucia Regina
Saheki,Mauricio Naoto
Miranda,Luciana de Freitas Campos
Schubach,Armando de Oliveira
Valete-Rosalino,Cláudia Maria
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ferreira Terceiro,Benivaldo Ramos
Torraca,Tania Salgado de Souza
Braga,Frederico Pereira Bom
Martins,Ana Cristina da Costa
Brahim,Lucia Regina
Saheki,Mauricio Naoto
Miranda,Luciana de Freitas Campos
Schubach,Armando de Oliveira
Valete-Rosalino,Cláudia Maria
dc.subject.por.fl_str_mv Mucosal leishmaniasis
Therapy
Pentamidine isethionate
topic Mucosal leishmaniasis
Therapy
Pentamidine isethionate
description Abstract In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate. We report the case of a patient with severe mucosal lesions caused by Leishmania (Viannia) braziliensis that were difficult to treat. Over a 14-year period, the patient showed low adherence and three treatment attempts with meglumine antimoniate failed. Additionally, there was an unsatisfactory response to liposomal amphotericin B and nephrotoxicity when using amphotericin B deoxycholate that persisted after new treatment attempt with liposomal amphotericin B. Finally, healing was achieved with pentamidine isethionate and maintained during nine months of monitoring.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100700
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100700
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0037-8682-0236-2018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.52 2019
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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