A clinico-pathological study of 163 untreated cases of chronic hepatitis C

Detalhes bibliográficos
Autor(a) principal: Graf,Joachim
Data de Publicação: 1996
Outros Autores: Toriyama,Kan, Itakura,Hideyo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000100005
Resumo: We performed a clinico-pathological study of 163 untreated cases of chronic hepatitis C. Eighty five percent of the patients were clinically asymptomatic and their physical examinations sbowed unremarkable or minimal changes at the time of the liver biopsy Liver function tests tended to present slight abnormalities, involving mild elevations of the activity of the aminotransferases and gamma-glutamil transferase levels. In spite of these mild abnormalities advanced chronic liver disease ivas histologically detected in eighty nine percent of the patients, mainly showing chronic active hepatitis. The most characteristic histological finding ivas an interlobular bile duct damage which correlated with the presence of tymphoid aggregates in the portal tracts and with the development of fibrosis.
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spelling A clinico-pathological study of 163 untreated cases of chronic hepatitis CChronic hepatitis CBile duct damage Lymphoid aggregateHistopathologyWe performed a clinico-pathological study of 163 untreated cases of chronic hepatitis C. Eighty five percent of the patients were clinically asymptomatic and their physical examinations sbowed unremarkable or minimal changes at the time of the liver biopsy Liver function tests tended to present slight abnormalities, involving mild elevations of the activity of the aminotransferases and gamma-glutamil transferase levels. In spite of these mild abnormalities advanced chronic liver disease ivas histologically detected in eighty nine percent of the patients, mainly showing chronic active hepatitis. The most characteristic histological finding ivas an interlobular bile duct damage which correlated with the presence of tymphoid aggregates in the portal tracts and with the development of fibrosis.Sociedade Brasileira de Medicina Tropical - SBMT1996-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000100005Revista da Sociedade Brasileira de Medicina Tropical v.29 n.1 1996reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86821996000100005info:eu-repo/semantics/openAccessGraf,JoachimToriyama,KanItakura,Hideyoeng2013-04-09T00:00:00Zoai:scielo:S0037-86821996000100005Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2013-04-09T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false
dc.title.none.fl_str_mv A clinico-pathological study of 163 untreated cases of chronic hepatitis C
title A clinico-pathological study of 163 untreated cases of chronic hepatitis C
spellingShingle A clinico-pathological study of 163 untreated cases of chronic hepatitis C
Graf,Joachim
Chronic hepatitis C
Bile duct damage Lymphoid aggregate
Histopathology
title_short A clinico-pathological study of 163 untreated cases of chronic hepatitis C
title_full A clinico-pathological study of 163 untreated cases of chronic hepatitis C
title_fullStr A clinico-pathological study of 163 untreated cases of chronic hepatitis C
title_full_unstemmed A clinico-pathological study of 163 untreated cases of chronic hepatitis C
title_sort A clinico-pathological study of 163 untreated cases of chronic hepatitis C
author Graf,Joachim
author_facet Graf,Joachim
Toriyama,Kan
Itakura,Hideyo
author_role author
author2 Toriyama,Kan
Itakura,Hideyo
author2_role author
author
dc.contributor.author.fl_str_mv Graf,Joachim
Toriyama,Kan
Itakura,Hideyo
dc.subject.por.fl_str_mv Chronic hepatitis C
Bile duct damage Lymphoid aggregate
Histopathology
topic Chronic hepatitis C
Bile duct damage Lymphoid aggregate
Histopathology
description We performed a clinico-pathological study of 163 untreated cases of chronic hepatitis C. Eighty five percent of the patients were clinically asymptomatic and their physical examinations sbowed unremarkable or minimal changes at the time of the liver biopsy Liver function tests tended to present slight abnormalities, involving mild elevations of the activity of the aminotransferases and gamma-glutamil transferase levels. In spite of these mild abnormalities advanced chronic liver disease ivas histologically detected in eighty nine percent of the patients, mainly showing chronic active hepatitis. The most characteristic histological finding ivas an interlobular bile duct damage which correlated with the presence of tymphoid aggregates in the portal tracts and with the development of fibrosis.
publishDate 1996
dc.date.none.fl_str_mv 1996-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000100005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821996000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0037-86821996000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical v.29 n.1 1996
reponame:Revista da Sociedade Brasileira de Medicina Tropical
instname:Sociedade Brasileira de Medicina Tropical (SBMT)
instacron:SBMT
instname_str Sociedade Brasileira de Medicina Tropical (SBMT)
instacron_str SBMT
institution SBMT
reponame_str Revista da Sociedade Brasileira de Medicina Tropical
collection Revista da Sociedade Brasileira de Medicina Tropical
repository.name.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)
repository.mail.fl_str_mv ||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br
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