Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista da Sociedade Brasileira de Medicina Tropical |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600005 |
Resumo: | INTRODUCTION: The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. METHODS: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. RESULTS: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. CONCLUSIONS: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children. |
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Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, BrazilHIVVertical transmission of infectious diseaseZidovudinePost-exposure prophylaxisINTRODUCTION: The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. METHODS: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. RESULTS: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. CONCLUSIONS: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children.Sociedade Brasileira de Medicina Tropical - SBMT2012-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600005Revista da Sociedade Brasileira de Medicina Tropical v.45 n.6 2012reponame:Revista da Sociedade Brasileira de Medicina Tropicalinstname:Sociedade Brasileira de Medicina Tropical (SBMT)instacron:SBMT10.1590/S0037-86822012000600005info:eu-repo/semantics/openAccessLemos,Lígia Mara Dolce deRocha,Thaísa Fonseca SiqueiraConceição,Marcos Vinícius daSilva,Eduardo de LemosSantos,Alessandro Henrique da SilvaGurgel,Ricardo Queirozeng2013-01-04T00:00:00Zoai:scielo:S0037-86822012000600005Revistahttps://www.sbmt.org.br/portal/revista/ONGhttps://old.scielo.br/oai/scielo-oai.php||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br1678-98490037-8682opendoar:2013-01-04T00:00Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT)false |
dc.title.none.fl_str_mv |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
title |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
spellingShingle |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil Lemos,Lígia Mara Dolce de HIV Vertical transmission of infectious disease Zidovudine Post-exposure prophylaxis |
title_short |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
title_full |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
title_fullStr |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
title_full_unstemmed |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
title_sort |
Evaluation of preventive measures for mother-to-child transmission of HIV in Aracaju, State of Sergipe, Brazil |
author |
Lemos,Lígia Mara Dolce de |
author_facet |
Lemos,Lígia Mara Dolce de Rocha,Thaísa Fonseca Siqueira Conceição,Marcos Vinícius da Silva,Eduardo de Lemos Santos,Alessandro Henrique da Silva Gurgel,Ricardo Queiroz |
author_role |
author |
author2 |
Rocha,Thaísa Fonseca Siqueira Conceição,Marcos Vinícius da Silva,Eduardo de Lemos Santos,Alessandro Henrique da Silva Gurgel,Ricardo Queiroz |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lemos,Lígia Mara Dolce de Rocha,Thaísa Fonseca Siqueira Conceição,Marcos Vinícius da Silva,Eduardo de Lemos Santos,Alessandro Henrique da Silva Gurgel,Ricardo Queiroz |
dc.subject.por.fl_str_mv |
HIV Vertical transmission of infectious disease Zidovudine Post-exposure prophylaxis |
topic |
HIV Vertical transmission of infectious disease Zidovudine Post-exposure prophylaxis |
description |
INTRODUCTION: The main route of human immunodeficiency virus (HIV) infection in children is from mother to child. The preventive measures established for the Aids Clinical Trial Group protocol 076 (ACTG 076) significantly reduces HIV vertical transmission rates. This study aims to evaluate the implementation of the ACTG 076 protocol in the maternity units of State of Sergipe, Brazilian northeast. METHODS: This is a descriptive, retrospective study with a quantitative approach, with HIV positive women and children exposed, attending a Maternity reference for high-risk pregnancies. Data were obtained from patient records registered in the years 1994 to 2010. RESULTS: Amongst the 110 pregnant women and exposed newborns, the ACTG 076 protocol was fully utilized in only 31.8% of the participants. During the prenatal period, zidovudine (ZDV) was taken by 79.1% of the pregnant women. Only 49.1% of HIV seropositive patients used ZDV during delivery. Two (1.8%) children were considered infected and 50 (45.5%) do not have a conclusive diagnosis to date. CONCLUSIONS: There were significant deficiencies in the prevention of mother-to-child transmission of HIV, including lack of compliance with the three phases of the ACTG 076 protocol; inadequacies in prenatal care; inappropriate mode of delivery and lack of adequate follow up of exposed children. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000600005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0037-86822012000600005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
dc.source.none.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical v.45 n.6 2012 reponame:Revista da Sociedade Brasileira de Medicina Tropical instname:Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
instname_str |
Sociedade Brasileira de Medicina Tropical (SBMT) |
instacron_str |
SBMT |
institution |
SBMT |
reponame_str |
Revista da Sociedade Brasileira de Medicina Tropical |
collection |
Revista da Sociedade Brasileira de Medicina Tropical |
repository.name.fl_str_mv |
Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT) |
repository.mail.fl_str_mv |
||dalmo@rsbmt.uftm.edu.br|| rsbmt@rsbmt.uftm.edu.br |
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1752122158181515264 |