Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian Journal of Veterinary Medicine |
Texto Completo: | https://rbmv.org/BJVM/article/view/292 |
Resumo: | ABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration. |
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Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissueTissue reaction and integration of polyamide and acrylonitrilebutadiene-styrene spheres in rat subcutaneous tissueABSimplantepoliamidaprótese ocularprototipagem rápidaratos WistarImplantocular prosthesiswistar ratsrapid prototypingpolyamideABSABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration.Foi investigado a reação tecidual e infiltração da poliamida e da acrilonitrila butadieno estireno (ABS) elaborados por prototipagem rápida. Para tanto, foram criados três grupos com seis ratos Wistar cada: no G1 os animais receberam implantes de ABS; no G2 os animais receberam implantes de poliamida; no grupo controle os animais receberam implantes de polimetilmetacrilato. Os implantes foram inseridos no subcutâneo da região torácica dorsal e os animais foram eutanasiados 60 dias após a inserção dos implantes para avaliação da reação e integração tecidual. As esferas foram seccionadas para avaliação macroscópica da infiltração tecidual e fragmentos da cápsula foram coletados para avaliação histopatológica. Na avaliação macroscópica, em todas as amostras foi observado presença de cápsula tecidual intensamente aderida aos implantes no G1, moderadamente aderida aos implantes no G2 e discretamente aderida aos implantes do grupo controle. Os fragmentos colhidos do G1 e G2 apresentaram aspectos histológicos semelhantes, entretanto a reação inflamatória observada nos animais do G1 foi mais discreta. Indí- cios de infecção ou reação de corpo estranho não foram observados em nenhum dos fragmentos de todos os grupos. Macroscopicamente foi observada infiltração tecidual no G1 e G2. Os resultados encontrados demonstram que os implantes foram bem tolerados e permitiram a integração tecidual.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2016-10-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfapplication/pdfhttps://rbmv.org/BJVM/article/view/292Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl. 1 (2016); 93-98Revista Brasileira de Medicina Veterinária; v. 38 n. Supl. 1 (2016); 93-982527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/292/201https://rbmv.org/BJVM/article/view/292/820Junior, Deusdete Conceição GomesNassar, Eduardo JoséNeto, Francisco de Assis DóreaLima, Alessandra EstrelaHonsho, Cristiane dos SantosFilho, Emanoel Ferreira MartinsOriá, Arianne Pontesinfo:eu-repo/semantics/openAccess2020-12-23T17:34:01Zoai:ojs.rbmv.org:article/292Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:34:01Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
dc.title.none.fl_str_mv |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue Tissue reaction and integration of polyamide and acrylonitrilebutadiene-styrene spheres in rat subcutaneous tissue |
title |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
spellingShingle |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue Junior, Deusdete Conceição Gomes ABS implante poliamida prótese ocular prototipagem rápida ratos Wistar Implant ocular prosthesis wistar rats rapid prototyping polyamide ABS |
title_short |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
title_full |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
title_fullStr |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
title_full_unstemmed |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
title_sort |
Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue |
author |
Junior, Deusdete Conceição Gomes |
author_facet |
Junior, Deusdete Conceição Gomes Nassar, Eduardo José Neto, Francisco de Assis Dórea Lima, Alessandra Estrela Honsho, Cristiane dos Santos Filho, Emanoel Ferreira Martins Oriá, Arianne Pontes |
author_role |
author |
author2 |
Nassar, Eduardo José Neto, Francisco de Assis Dórea Lima, Alessandra Estrela Honsho, Cristiane dos Santos Filho, Emanoel Ferreira Martins Oriá, Arianne Pontes |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Junior, Deusdete Conceição Gomes Nassar, Eduardo José Neto, Francisco de Assis Dórea Lima, Alessandra Estrela Honsho, Cristiane dos Santos Filho, Emanoel Ferreira Martins Oriá, Arianne Pontes |
dc.subject.por.fl_str_mv |
ABS implante poliamida prótese ocular prototipagem rápida ratos Wistar Implant ocular prosthesis wistar rats rapid prototyping polyamide ABS |
topic |
ABS implante poliamida prótese ocular prototipagem rápida ratos Wistar Implant ocular prosthesis wistar rats rapid prototyping polyamide ABS |
description |
ABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-10-26 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer reviewed Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/292 |
url |
https://rbmv.org/BJVM/article/view/292 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/292/201 https://rbmv.org/BJVM/article/view/292/820 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl. 1 (2016); 93-98 Revista Brasileira de Medicina Veterinária; v. 38 n. Supl. 1 (2016); 93-98 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
instname_str |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
instacron_str |
SBMV |
institution |
SBMV |
reponame_str |
Brazilian Journal of Veterinary Medicine |
collection |
Brazilian Journal of Veterinary Medicine |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
repository.mail.fl_str_mv |
contato.rbmv@gmail.com |
_version_ |
1798313107122028544 |