Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue

Detalhes bibliográficos
Autor(a) principal: Junior, Deusdete Conceição Gomes
Data de Publicação: 2016
Outros Autores: Nassar, Eduardo José, Neto, Francisco de Assis Dórea, Lima, Alessandra Estrela, Honsho, Cristiane dos Santos, Filho, Emanoel Ferreira Martins, Oriá, Arianne Pontes
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Medicine
Texto Completo: https://rbmv.org/BJVM/article/view/292
Resumo: ABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration.
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spelling Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissueTissue reaction and integration of polyamide and acrylonitrilebutadiene-styrene spheres in rat subcutaneous tissueABSimplantepoliamidaprótese ocularprototipagem rápidaratos WistarImplantocular prosthesiswistar ratsrapid prototypingpolyamideABSABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration.Foi investigado a reação tecidual e infiltração da poliamida e da acrilonitrila butadieno estireno (ABS) elaborados por prototipagem rápida. Para tanto, foram criados três grupos com seis ratos Wistar cada: no G1 os animais receberam implantes de ABS; no G2 os animais receberam implantes de poliamida; no grupo controle os animais receberam implantes de polimetilmetacrilato. Os implantes foram inseridos no subcutâneo da região torácica dorsal e os animais foram eutanasiados 60 dias após a inserção dos implantes para avaliação da reação e integração tecidual. As esferas foram seccionadas para avaliação macroscópica da infiltração tecidual e fragmentos da cápsula foram coletados para avaliação histopatológica. Na avaliação macroscópica, em todas as amostras foi observado presença de cápsula tecidual intensamente aderida aos implantes no G1, moderadamente aderida aos implantes no G2 e discretamente aderida aos implantes do grupo controle. Os fragmentos colhidos do G1 e G2 apresentaram aspectos histológicos semelhantes, entretanto a reação inflamatória observada nos animais do G1 foi mais discreta. Indí- cios de infecção ou reação de corpo estranho não foram observados em nenhum dos fragmentos de todos os grupos. Macroscopicamente foi observada infiltração tecidual no G1 e G2. Os resultados encontrados demonstram que os implantes foram bem tolerados e permitiram a integração tecidual.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2016-10-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdfapplication/pdfhttps://rbmv.org/BJVM/article/view/292Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl. 1 (2016); 93-98Revista Brasileira de Medicina Veterinária; v. 38 n. Supl. 1 (2016); 93-982527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVporhttps://rbmv.org/BJVM/article/view/292/201https://rbmv.org/BJVM/article/view/292/820Junior, Deusdete Conceição GomesNassar, Eduardo JoséNeto, Francisco de Assis DóreaLima, Alessandra EstrelaHonsho, Cristiane dos SantosFilho, Emanoel Ferreira MartinsOriá, Arianne Pontesinfo:eu-repo/semantics/openAccess2020-12-23T17:34:01Zoai:ojs.rbmv.org:article/292Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2020-12-23T17:34:01Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false
dc.title.none.fl_str_mv Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
Tissue reaction and integration of polyamide and acrylonitrilebutadiene-styrene spheres in rat subcutaneous tissue
title Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
spellingShingle Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
Junior, Deusdete Conceição Gomes
ABS
implante
poliamida
prótese ocular
prototipagem rápida
ratos Wistar
Implant
ocular prosthesis
wistar rats
rapid prototyping
polyamide
ABS
title_short Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
title_full Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
title_fullStr Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
title_full_unstemmed Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
title_sort Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue
author Junior, Deusdete Conceição Gomes
author_facet Junior, Deusdete Conceição Gomes
Nassar, Eduardo José
Neto, Francisco de Assis Dórea
Lima, Alessandra Estrela
Honsho, Cristiane dos Santos
Filho, Emanoel Ferreira Martins
Oriá, Arianne Pontes
author_role author
author2 Nassar, Eduardo José
Neto, Francisco de Assis Dórea
Lima, Alessandra Estrela
Honsho, Cristiane dos Santos
Filho, Emanoel Ferreira Martins
Oriá, Arianne Pontes
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Junior, Deusdete Conceição Gomes
Nassar, Eduardo José
Neto, Francisco de Assis Dórea
Lima, Alessandra Estrela
Honsho, Cristiane dos Santos
Filho, Emanoel Ferreira Martins
Oriá, Arianne Pontes
dc.subject.por.fl_str_mv ABS
implante
poliamida
prótese ocular
prototipagem rápida
ratos Wistar
Implant
ocular prosthesis
wistar rats
rapid prototyping
polyamide
ABS
topic ABS
implante
poliamida
prótese ocular
prototipagem rápida
ratos Wistar
Implant
ocular prosthesis
wistar rats
rapid prototyping
polyamide
ABS
description ABSTRACT. Gomes Junior D.C., Nassar E.J., Dórea Neto F.A., Estrela-Lima A, Honsho C. dos S., Martins Filho E. & Oriá A.P. Tissue reaction and integration of polyamide and acrylonitrile-butadiene-styrene spheres in rat subcutaneous tissue. [Reação e integração tecidual de esferas de acrilonitrila butadieno estireno e poliamida em subcutâneo de ratos.] Revista Brasileira de Medicina Veterinária, 38(Supl.1):93-98, 2016. Programa de Pós-Graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia, Av. Ademar de Barros, 500, Ondina, Salvador, BA 40170-110, Brasil. E-mail: arianneoria@ufba.br We investigated the infiltration and tissue reaction of polyamide and acrylonitrile-butadiene-styrene (ABS) spheres prepared by rapid prototyping. Accordingly, three groups of six Wistar rats each were formed; G1, where animals received ABS implants; G2, where animals received polyamide implants and the control group where the animals received polymethylmethacrylate implants. Implants were inserted subcutaneously in the dorsal thoracic region and the animals were euthanized 60 days after implant insertion to evaluate tissue reaction and incorporation. The spheres were sectioned for macroscopic evaluation of tissue infiltration, and capsule fragments were collected for histopathologic evaluation. In macroscopic evaluation, all samples showed the presence of a thin tissue capsule that was strongly adhered to the implants in G1, moderately adhered to the implants in G2 and discretely adhered to the control group. The collected fragments of G1 and G2 had a similar appearance on histopathologic examination, however the inflammatory reaction observed in the animals of G1 was more discreet. Evidence of infection or foreign body reaction was not observed in any of the fragments, and all groups showed a mild mononuclear inflammatory reaction. Macroscopically, tissue infiltration was observed in G1 and G2. The results showed that the implants were well tolerated and allowed tissue integration.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-26
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
peer reviewed
Avaliado pelos pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbmv.org/BJVM/article/view/292
url https://rbmv.org/BJVM/article/view/292
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbmv.org/BJVM/article/view/292/201
https://rbmv.org/BJVM/article/view/292/820
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
publisher.none.fl_str_mv Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Medicine; Vol. 38 No. Supl. 1 (2016); 93-98
Revista Brasileira de Medicina Veterinária; v. 38 n. Supl. 1 (2016); 93-98
2527-2179
0100-2430
reponame:Brazilian Journal of Veterinary Medicine
instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron:SBMV
instname_str Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
instacron_str SBMV
institution SBMV
reponame_str Brazilian Journal of Veterinary Medicine
collection Brazilian Journal of Veterinary Medicine
repository.name.fl_str_mv Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)
repository.mail.fl_str_mv contato.rbmv@gmail.com
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