Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study

Detalhes bibliográficos
Autor(a) principal: Gomes Júnior,D.C.
Data de Publicação: 2016
Outros Autores: Nassar,E.J., Dórea Neto,F.A., Lima,A.E., Martins Filho,E.F., Oriá,A.P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Arquivo brasileiro de medicina veterinária e zootecnia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501168
Resumo: ABSTRACT The purpose of this study was to evaluate acrylonitrile butadiene styrene (ABS) and polyamide implants in rabbits submitted to evisceration at the macroscopic and microstructure level and to assess clinical response and histopathological changes as well. For the experimental study implants of 12mm diameter were prepared by rapid prototyping, weighed and the outer and inner surfaces evaluated macroscopically and by electron microscopy. In addition, a compression test was performed and ultrastructural damage was then determined. After evisceration of the left eyeball, nine New Zealand rabbits received ABS implants and nine others received polyamide implants. The animals were assessed daily for 15 days after surgery and every seven days until the end of the study (90 days). Histopathological evaluation was performed at 15, 45 and 90 days after surgery. The ABS implants weighed approximately 0.44g, while the polyamide ones weighed 0.61g. Scanning electron microscopy demonstrated that the ABS implants had regular-sized, equidistant micropores, while the polyamide ones showed micropores of various sizes. The force required to fracture the ABS implant was 14.39 ±0.60 Mpa, while for the polyamide one, it was 16.80 ±1.05 Mpa. Fifteen days after surgery, we observed centripetal tissue infiltration and scarce inflammatory infiltrate. Implants may be used in the filling of anophthalmic cavities, because they are inert, biocompatible and allow tissue integration.
id UFMG-8_4be9325fe1c6e559d3ad7a819e778fd7
oai_identifier_str oai:scielo:S0102-09352016000501168
network_acronym_str UFMG-8
network_name_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository_id_str
spelling Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology studyrabbitsocular prosthesispolymersABSTRACT The purpose of this study was to evaluate acrylonitrile butadiene styrene (ABS) and polyamide implants in rabbits submitted to evisceration at the macroscopic and microstructure level and to assess clinical response and histopathological changes as well. For the experimental study implants of 12mm diameter were prepared by rapid prototyping, weighed and the outer and inner surfaces evaluated macroscopically and by electron microscopy. In addition, a compression test was performed and ultrastructural damage was then determined. After evisceration of the left eyeball, nine New Zealand rabbits received ABS implants and nine others received polyamide implants. The animals were assessed daily for 15 days after surgery and every seven days until the end of the study (90 days). Histopathological evaluation was performed at 15, 45 and 90 days after surgery. The ABS implants weighed approximately 0.44g, while the polyamide ones weighed 0.61g. Scanning electron microscopy demonstrated that the ABS implants had regular-sized, equidistant micropores, while the polyamide ones showed micropores of various sizes. The force required to fracture the ABS implant was 14.39 ±0.60 Mpa, while for the polyamide one, it was 16.80 ±1.05 Mpa. Fifteen days after surgery, we observed centripetal tissue infiltration and scarce inflammatory infiltrate. Implants may be used in the filling of anophthalmic cavities, because they are inert, biocompatible and allow tissue integration.Universidade Federal de Minas Gerais, Escola de Veterinária2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501168Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.68 n.5 2016reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)instname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMG10.1590/1678-4162-8680info:eu-repo/semantics/openAccessGomes Júnior,D.C.Nassar,E.J.Dórea Neto,F.A.Lima,A.E.Martins Filho,E.F.Oriá,A.P.eng2016-11-07T00:00:00Zoai:scielo:S0102-09352016000501168Revistahttps://www.scielo.br/j/abmvz/PUBhttps://old.scielo.br/oai/scielo-oai.phpjournal@vet.ufmg.br||abmvz.artigo@abmvz.org.br1678-41620102-0935opendoar:2016-11-07T00:00Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)false
dc.title.none.fl_str_mv Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
title Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
spellingShingle Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
Gomes Júnior,D.C.
rabbits
ocular prosthesis
polymers
title_short Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
title_full Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
title_fullStr Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
title_full_unstemmed Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
title_sort Experimental acrylonitrile butadiene styrene and polyamide evisceration implant: a rabbit clinical and histopathology study
author Gomes Júnior,D.C.
author_facet Gomes Júnior,D.C.
Nassar,E.J.
Dórea Neto,F.A.
Lima,A.E.
Martins Filho,E.F.
Oriá,A.P.
author_role author
author2 Nassar,E.J.
Dórea Neto,F.A.
Lima,A.E.
Martins Filho,E.F.
Oriá,A.P.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes Júnior,D.C.
Nassar,E.J.
Dórea Neto,F.A.
Lima,A.E.
Martins Filho,E.F.
Oriá,A.P.
dc.subject.por.fl_str_mv rabbits
ocular prosthesis
polymers
topic rabbits
ocular prosthesis
polymers
description ABSTRACT The purpose of this study was to evaluate acrylonitrile butadiene styrene (ABS) and polyamide implants in rabbits submitted to evisceration at the macroscopic and microstructure level and to assess clinical response and histopathological changes as well. For the experimental study implants of 12mm diameter were prepared by rapid prototyping, weighed and the outer and inner surfaces evaluated macroscopically and by electron microscopy. In addition, a compression test was performed and ultrastructural damage was then determined. After evisceration of the left eyeball, nine New Zealand rabbits received ABS implants and nine others received polyamide implants. The animals were assessed daily for 15 days after surgery and every seven days until the end of the study (90 days). Histopathological evaluation was performed at 15, 45 and 90 days after surgery. The ABS implants weighed approximately 0.44g, while the polyamide ones weighed 0.61g. Scanning electron microscopy demonstrated that the ABS implants had regular-sized, equidistant micropores, while the polyamide ones showed micropores of various sizes. The force required to fracture the ABS implant was 14.39 ±0.60 Mpa, while for the polyamide one, it was 16.80 ±1.05 Mpa. Fifteen days after surgery, we observed centripetal tissue infiltration and scarce inflammatory infiltrate. Implants may be used in the filling of anophthalmic cavities, because they are inert, biocompatible and allow tissue integration.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501168
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000501168
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-4162-8680
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
publisher.none.fl_str_mv Universidade Federal de Minas Gerais, Escola de Veterinária
dc.source.none.fl_str_mv Arquivo Brasileiro de Medicina Veterinária e Zootecnia v.68 n.5 2016
reponame:Arquivo brasileiro de medicina veterinária e zootecnia (Online)
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Arquivo brasileiro de medicina veterinária e zootecnia (Online)
collection Arquivo brasileiro de medicina veterinária e zootecnia (Online)
repository.name.fl_str_mv Arquivo brasileiro de medicina veterinária e zootecnia (Online) - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv journal@vet.ufmg.br||abmvz.artigo@abmvz.org.br
_version_ 1750220889990889472