Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Veterinary Medicine |
Texto Completo: | https://rbmv.org/BJVM/article/view/1230 |
Resumo: | Liver lipidosis is a metabolic disorder mostly observed in high yielding dairy cattle, especially during the transition period. The aim of this study was to determine the correlation between hepatic lipid infiltration, biochemical indicators of liver function, and body condition score (BCS) variation in dairy cows. Fifty-one multiparous Holstein cows raised in a confined system were evaluated. Liver biopsies and blood samples were collected, and BCS was measured on days 3 and 28 postpartum. Lipid infiltration was determined by histologic examination. The plasma activity of aspartate aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase and concentration of beta-hydroxybutyrate, non-esterified fatty acids, albumin, total bilirubin, and cholesterol were determined. BCS was measured using objective (camera) and subjective (visual) methods. Mild lipid infiltration was found in 3.92% of cows sampled on day 3 and 5.88% on day 28. Bilirubin was significantly higher on day 3 than on day 28 postpartum, and cholesterol was significantly higher on day 28 than on day 3 in all cows. There was no difference in biochemical analytes between cows with and without lipidosis. On day 3, mean subjective BCS was 3.10 and objective BCS was 3.16, while on day 28, these scores were 2.91 and 2.99, respectively. The calculated liver function index (LFI) was found to be a more sensitive indicator of liver function than the hepatic analytes evaluated. No correlation between BCS variation and lipid infiltration was found. Cholesterol and bilirubin levels showed the most remarkable changes during the early postpartum period. LFI is a potential indicator of postpartum liver function. |
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Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows Correlação entre lipidose hepática, variação da condição corporal e analitos hepáticos em bovinos leiteiros hepatic lipidosis, weight, blood metabolites, hepatic function, calculated liver function index, dairy cattle.lipidose hepática, peso, metabolitos sanguíneos, função hepática, índice calculado de função hepática, bovinos de leiteLiver lipidosis is a metabolic disorder mostly observed in high yielding dairy cattle, especially during the transition period. The aim of this study was to determine the correlation between hepatic lipid infiltration, biochemical indicators of liver function, and body condition score (BCS) variation in dairy cows. Fifty-one multiparous Holstein cows raised in a confined system were evaluated. Liver biopsies and blood samples were collected, and BCS was measured on days 3 and 28 postpartum. Lipid infiltration was determined by histologic examination. The plasma activity of aspartate aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase and concentration of beta-hydroxybutyrate, non-esterified fatty acids, albumin, total bilirubin, and cholesterol were determined. BCS was measured using objective (camera) and subjective (visual) methods. Mild lipid infiltration was found in 3.92% of cows sampled on day 3 and 5.88% on day 28. Bilirubin was significantly higher on day 3 than on day 28 postpartum, and cholesterol was significantly higher on day 28 than on day 3 in all cows. There was no difference in biochemical analytes between cows with and without lipidosis. On day 3, mean subjective BCS was 3.10 and objective BCS was 3.16, while on day 28, these scores were 2.91 and 2.99, respectively. The calculated liver function index (LFI) was found to be a more sensitive indicator of liver function than the hepatic analytes evaluated. No correlation between BCS variation and lipid infiltration was found. Cholesterol and bilirubin levels showed the most remarkable changes during the early postpartum period. LFI is a potential indicator of postpartum liver function.A lipidose hepática é um distúrbio metabólico principalmente observado nos bovinos de leite de alto rendimento, especialmente no período de transição. O objetivo deste estudo foi determinar a correlação entre infiltração lipídica hepática, indicadores bioquímicos de função hepática e variação da condição corporal em bovinos leiteiros. Foram avaliadas cinquenta e um vacas multíparas de raça Holandesa em confinamento. Coletaram-se biopsias de fígado e amostras de sangue, e a condição corporal (BCS) aferiu-se nos dias 3 e 28 pós-parto. A infiltração lipídica determinou-se mediante avaliação histológica. Mensuraram-se a atividade da aspartato aminotransferase, fosfatase alcalina e da gama-glutamil transferase, concentração de beta-hidroxibutirato, ácidos graxos não esterificados, albumina, bilirrubina total e colesterol. A BCS mediu-se utilizando método objetivo (câmera) e subjetivo (visualmente). Observou-se discreta infiltração lipídica em 3,92% dos bovinos amostrados no dia 3 e 5,88% no dia 28. Em todos os bovinos a bilirrubina foi significativamente mais alta no dia 3 do que no dia 28 e o colesterol foi superior no dia 28 do que no dia 3. Não houve diferença nos analitos bioquímicos dos bovinos com e sem lipidose. No dia 3, a média subjetiva da BCS foi 3,10 e a objetiva 3,16, enquanto no dia 28, obtiveram-se valores de 2,91, e 2,99 respectivamente. O índice calculado de função hepática mostrou ser um indicador mais sensível da função hepática do que os analitos avaliados individualmente. Não houve correlação entre a variação do BCS e infiltração lipídica.Sociedade de Medicina Veterinária do Estado do Rio de Janeiro.2022-02-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpeer reviewedAvaliado pelos paresapplication/pdftext/xmlhttps://rbmv.org/BJVM/article/view/123010.29374/2527-2179.bjvm005121Brazilian Journal of Veterinary Medicine; Vol. 44 (2022); e005121Revista Brasileira de Medicina Veterinária; v. 44 (2022); e0051212527-21790100-2430reponame:Brazilian Journal of Veterinary Medicineinstname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)instacron:SBMVenghttps://rbmv.org/BJVM/article/view/1230/1112https://rbmv.org/BJVM/article/view/1230/1170Copyright (c) 2022 Chester Patrique Batista, Rodrigo Schallenberger Gonçalves, Laura Victoria Quishpe Contreras , Stella de Faria Valle, Félix Gonzálezhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBatista, Chester PatriqueGonçalves, Rodrigo SchallenbergerContreras , Laura Victoria QuishpeValle, Stella de FariaGonzález, Félix2022-06-25T21:01:39Zoai:ojs.rbmv.org:article/1230Revistahttps://rbmv.org/BJVMONGhttps://rbmv.org/BJVM/oaicontato.rbmv@gmail.com2527-21790100-2430opendoar:2022-06-25T21:01:39Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ)false |
dc.title.none.fl_str_mv |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows Correlação entre lipidose hepática, variação da condição corporal e analitos hepáticos em bovinos leiteiros |
title |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
spellingShingle |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows Batista, Chester Patrique hepatic lipidosis, weight, blood metabolites, hepatic function, calculated liver function index, dairy cattle. lipidose hepática, peso, metabolitos sanguíneos, função hepática, índice calculado de função hepática, bovinos de leite |
title_short |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
title_full |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
title_fullStr |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
title_full_unstemmed |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
title_sort |
Correlation between liver lipidosis, body condition score variation, and hepatic analytes in dairy cows |
author |
Batista, Chester Patrique |
author_facet |
Batista, Chester Patrique Gonçalves, Rodrigo Schallenberger Contreras , Laura Victoria Quishpe Valle, Stella de Faria González, Félix |
author_role |
author |
author2 |
Gonçalves, Rodrigo Schallenberger Contreras , Laura Victoria Quishpe Valle, Stella de Faria González, Félix |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Batista, Chester Patrique Gonçalves, Rodrigo Schallenberger Contreras , Laura Victoria Quishpe Valle, Stella de Faria González, Félix |
dc.subject.por.fl_str_mv |
hepatic lipidosis, weight, blood metabolites, hepatic function, calculated liver function index, dairy cattle. lipidose hepática, peso, metabolitos sanguíneos, função hepática, índice calculado de função hepática, bovinos de leite |
topic |
hepatic lipidosis, weight, blood metabolites, hepatic function, calculated liver function index, dairy cattle. lipidose hepática, peso, metabolitos sanguíneos, função hepática, índice calculado de função hepática, bovinos de leite |
description |
Liver lipidosis is a metabolic disorder mostly observed in high yielding dairy cattle, especially during the transition period. The aim of this study was to determine the correlation between hepatic lipid infiltration, biochemical indicators of liver function, and body condition score (BCS) variation in dairy cows. Fifty-one multiparous Holstein cows raised in a confined system were evaluated. Liver biopsies and blood samples were collected, and BCS was measured on days 3 and 28 postpartum. Lipid infiltration was determined by histologic examination. The plasma activity of aspartate aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase and concentration of beta-hydroxybutyrate, non-esterified fatty acids, albumin, total bilirubin, and cholesterol were determined. BCS was measured using objective (camera) and subjective (visual) methods. Mild lipid infiltration was found in 3.92% of cows sampled on day 3 and 5.88% on day 28. Bilirubin was significantly higher on day 3 than on day 28 postpartum, and cholesterol was significantly higher on day 28 than on day 3 in all cows. There was no difference in biochemical analytes between cows with and without lipidosis. On day 3, mean subjective BCS was 3.10 and objective BCS was 3.16, while on day 28, these scores were 2.91 and 2.99, respectively. The calculated liver function index (LFI) was found to be a more sensitive indicator of liver function than the hepatic analytes evaluated. No correlation between BCS variation and lipid infiltration was found. Cholesterol and bilirubin levels showed the most remarkable changes during the early postpartum period. LFI is a potential indicator of postpartum liver function. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion peer reviewed Avaliado pelos pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rbmv.org/BJVM/article/view/1230 10.29374/2527-2179.bjvm005121 |
url |
https://rbmv.org/BJVM/article/view/1230 |
identifier_str_mv |
10.29374/2527-2179.bjvm005121 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rbmv.org/BJVM/article/view/1230/1112 https://rbmv.org/BJVM/article/view/1230/1170 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/xml |
dc.publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
publisher.none.fl_str_mv |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro. |
dc.source.none.fl_str_mv |
Brazilian Journal of Veterinary Medicine; Vol. 44 (2022); e005121 Revista Brasileira de Medicina Veterinária; v. 44 (2022); e005121 2527-2179 0100-2430 reponame:Brazilian Journal of Veterinary Medicine instname:Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) instacron:SBMV |
instname_str |
Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
instacron_str |
SBMV |
institution |
SBMV |
reponame_str |
Brazilian Journal of Veterinary Medicine |
collection |
Brazilian Journal of Veterinary Medicine |
repository.name.fl_str_mv |
Brazilian Journal of Veterinary Medicine - Sociedade de Medicina Veterinária do Estado do Rio de Janeiro (SOMVERJ) |
repository.mail.fl_str_mv |
contato.rbmv@gmail.com |
_version_ |
1798313111662362624 |