Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Nefrologia |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489 |
Resumo: | Abstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases. |
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Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reportsGlomerulosclerosis, Focal SegmentalDengue VirusNephrotic SyndromeRenal Insufficiency, ChronicAbstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases.Sociedade Brasileira de Nefrologia2020-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489Brazilian Journal of Nephrology v.42 n.4 2020reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.1590/2175-8239-jbn-2019-0237info:eu-repo/semantics/openAccessQueiroz,Patrícia CruzJorge,Ana Elisa SouzaMourão,Plínio Henrique VazPenido,Maria Goretti Moreira Guimarãeseng2021-01-19T00:00:00Zoai:scielo:S0101-28002020000400489Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2021-01-19T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false |
dc.title.none.fl_str_mv |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
title |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
spellingShingle |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports Queiroz,Patrícia Cruz Glomerulosclerosis, Focal Segmental Dengue Virus Nephrotic Syndrome Renal Insufficiency, Chronic |
title_short |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
title_full |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
title_fullStr |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
title_full_unstemmed |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
title_sort |
Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports |
author |
Queiroz,Patrícia Cruz |
author_facet |
Queiroz,Patrícia Cruz Jorge,Ana Elisa Souza Mourão,Plínio Henrique Vaz Penido,Maria Goretti Moreira Guimarães |
author_role |
author |
author2 |
Jorge,Ana Elisa Souza Mourão,Plínio Henrique Vaz Penido,Maria Goretti Moreira Guimarães |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Queiroz,Patrícia Cruz Jorge,Ana Elisa Souza Mourão,Plínio Henrique Vaz Penido,Maria Goretti Moreira Guimarães |
dc.subject.por.fl_str_mv |
Glomerulosclerosis, Focal Segmental Dengue Virus Nephrotic Syndrome Renal Insufficiency, Chronic |
topic |
Glomerulosclerosis, Focal Segmental Dengue Virus Nephrotic Syndrome Renal Insufficiency, Chronic |
description |
Abstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/2175-8239-jbn-2019-0237 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Nefrologia |
dc.source.none.fl_str_mv |
Brazilian Journal of Nephrology v.42 n.4 2020 reponame:Jornal Brasileiro de Nefrologia instname:Sociedade Brasileira de Nefrologia (SBN) instacron:SBN |
instname_str |
Sociedade Brasileira de Nefrologia (SBN) |
instacron_str |
SBN |
institution |
SBN |
reponame_str |
Jornal Brasileiro de Nefrologia |
collection |
Jornal Brasileiro de Nefrologia |
repository.name.fl_str_mv |
Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN) |
repository.mail.fl_str_mv |
||jbn@sbn.org.br |
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1752122066130173952 |