Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports

Detalhes bibliográficos
Autor(a) principal: Queiroz,Patrícia Cruz
Data de Publicação: 2020
Outros Autores: Jorge,Ana Elisa Souza, Mourão,Plínio Henrique Vaz, Penido,Maria Goretti Moreira Guimarães
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489
Resumo: Abstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases.
id SBN-1_0bea990eab6828701e3bf40c353436e4
oai_identifier_str oai:scielo:S0101-28002020000400489
network_acronym_str SBN-1
network_name_str Jornal Brasileiro de Nefrologia
repository_id_str
spelling Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reportsGlomerulosclerosis, Focal SegmentalDengue VirusNephrotic SyndromeRenal Insufficiency, ChronicAbstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases.Sociedade Brasileira de Nefrologia2020-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489Brazilian Journal of Nephrology v.42 n.4 2020reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.1590/2175-8239-jbn-2019-0237info:eu-repo/semantics/openAccessQueiroz,Patrícia CruzJorge,Ana Elisa SouzaMourão,Plínio Henrique VazPenido,Maria Goretti Moreira Guimarãeseng2021-01-19T00:00:00Zoai:scielo:S0101-28002020000400489Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2021-01-19T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
title Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
spellingShingle Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
Queiroz,Patrícia Cruz
Glomerulosclerosis, Focal Segmental
Dengue Virus
Nephrotic Syndrome
Renal Insufficiency, Chronic
title_short Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
title_full Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
title_fullStr Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
title_full_unstemmed Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
title_sort Collapsing focal segmental glomerulosclerosis probably triggered by dengue virus infection - two case reports
author Queiroz,Patrícia Cruz
author_facet Queiroz,Patrícia Cruz
Jorge,Ana Elisa Souza
Mourão,Plínio Henrique Vaz
Penido,Maria Goretti Moreira Guimarães
author_role author
author2 Jorge,Ana Elisa Souza
Mourão,Plínio Henrique Vaz
Penido,Maria Goretti Moreira Guimarães
author2_role author
author
author
dc.contributor.author.fl_str_mv Queiroz,Patrícia Cruz
Jorge,Ana Elisa Souza
Mourão,Plínio Henrique Vaz
Penido,Maria Goretti Moreira Guimarães
dc.subject.por.fl_str_mv Glomerulosclerosis, Focal Segmental
Dengue Virus
Nephrotic Syndrome
Renal Insufficiency, Chronic
topic Glomerulosclerosis, Focal Segmental
Dengue Virus
Nephrotic Syndrome
Renal Insufficiency, Chronic
description Abstract The reported cases describe the association between collapsing focal segmental glomerulosclerosis (FSGS) and acute dengue virus infection. In both cases, patients were diagnosed with dengue virus infection and had a severe kidney disease, with nephrotic syndrome and acute kidney injury. Kidney biopsy was performed and showed collapsing FSGS. The first patient, a 27-year-old man, was diagnosed with dengue virus infection and developed nephrotic syndrome after two weeks of illness. He was treated with methylprednisolone for three days and intravenous furosemide. This patient evolved well, although his renal function did not fully recover. The second patient, a 32-year-old man, was diagnosed with a milder clinical presentation of dengue virus infection. He had a past medical history of nephrotic syndrome in childhood, which might have caused its relapse. This patient was treated with intravenous furosemide and also did not fully recover renal function. These cases highlight the possible implication of dengue virus infection in the etiology of collapsing variant of FSGS. Healthcare professionals should be prepared to identify similar cases.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400489
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/2175-8239-jbn-2019-0237
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.42 n.4 2020
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
instacron:SBN
instname_str Sociedade Brasileira de Nefrologia (SBN)
instacron_str SBN
institution SBN
reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
repository.name.fl_str_mv Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)
repository.mail.fl_str_mv ||jbn@sbn.org.br
_version_ 1752122066130173952