Vitamin D Toxicity

Detalhes bibliográficos
Autor(a) principal: Lim,Kenneth
Data de Publicação: 2020
Outros Autores: Thadhani,Ravi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Nefrologia
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000200238
Resumo: Abstract Fortification of food products with vitamin D was central to the eradication of rickets in the early parts of the 20th century in the United States. In the subsequent almost 100 years since, accumulating evidence has linked vitamin D deficiency to a variety of outcomes, and this has paralleled greater public interest and awareness of the health benefits of vitamin D. Supplements containing vitamin D are now widely available in both industrialized and developing countries, and many are in the form of unregulated formulations sold to the public with little guidance for safe administration. Together, this has contributed to a transition whereby a dramatic global increase in cases of vitamin D toxicity has been reported. Clinicians are now faced with the challenge of managing this condition that can present on a spectrum from asymptomatic to acute life-threatening complications. This article considers contemporary data on vitamin D toxicity, and diagnostic and management strategies relevant to clinical practice.
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spelling Vitamin D ToxicityVitamin DPoisoningToxicityHypercalcemiaAcute Kidney InjuryAbstract Fortification of food products with vitamin D was central to the eradication of rickets in the early parts of the 20th century in the United States. In the subsequent almost 100 years since, accumulating evidence has linked vitamin D deficiency to a variety of outcomes, and this has paralleled greater public interest and awareness of the health benefits of vitamin D. Supplements containing vitamin D are now widely available in both industrialized and developing countries, and many are in the form of unregulated formulations sold to the public with little guidance for safe administration. Together, this has contributed to a transition whereby a dramatic global increase in cases of vitamin D toxicity has been reported. Clinicians are now faced with the challenge of managing this condition that can present on a spectrum from asymptomatic to acute life-threatening complications. This article considers contemporary data on vitamin D toxicity, and diagnostic and management strategies relevant to clinical practice.Sociedade Brasileira de Nefrologia2020-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000200238Brazilian Journal of Nephrology v.42 n.2 2020reponame:Jornal Brasileiro de Nefrologiainstname:Sociedade Brasileira de Nefrologia (SBN)instacron:SBN10.1590/2175-8239-jbn-2019-0192info:eu-repo/semantics/openAccessLim,KennethThadhani,Ravieng2020-07-09T00:00:00Zoai:scielo:S0101-28002020000200238Revistahttp://www.bjn.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||jbn@sbn.org.br2175-82390101-2800opendoar:2020-07-09T00:00Jornal Brasileiro de Nefrologia - Sociedade Brasileira de Nefrologia (SBN)false
dc.title.none.fl_str_mv Vitamin D Toxicity
title Vitamin D Toxicity
spellingShingle Vitamin D Toxicity
Lim,Kenneth
Vitamin D
Poisoning
Toxicity
Hypercalcemia
Acute Kidney Injury
title_short Vitamin D Toxicity
title_full Vitamin D Toxicity
title_fullStr Vitamin D Toxicity
title_full_unstemmed Vitamin D Toxicity
title_sort Vitamin D Toxicity
author Lim,Kenneth
author_facet Lim,Kenneth
Thadhani,Ravi
author_role author
author2 Thadhani,Ravi
author2_role author
dc.contributor.author.fl_str_mv Lim,Kenneth
Thadhani,Ravi
dc.subject.por.fl_str_mv Vitamin D
Poisoning
Toxicity
Hypercalcemia
Acute Kidney Injury
topic Vitamin D
Poisoning
Toxicity
Hypercalcemia
Acute Kidney Injury
description Abstract Fortification of food products with vitamin D was central to the eradication of rickets in the early parts of the 20th century in the United States. In the subsequent almost 100 years since, accumulating evidence has linked vitamin D deficiency to a variety of outcomes, and this has paralleled greater public interest and awareness of the health benefits of vitamin D. Supplements containing vitamin D are now widely available in both industrialized and developing countries, and many are in the form of unregulated formulations sold to the public with little guidance for safe administration. Together, this has contributed to a transition whereby a dramatic global increase in cases of vitamin D toxicity has been reported. Clinicians are now faced with the challenge of managing this condition that can present on a spectrum from asymptomatic to acute life-threatening complications. This article considers contemporary data on vitamin D toxicity, and diagnostic and management strategies relevant to clinical practice.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-01
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/2175-8239-jbn-2019-0192
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dc.publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
publisher.none.fl_str_mv Sociedade Brasileira de Nefrologia
dc.source.none.fl_str_mv Brazilian Journal of Nephrology v.42 n.2 2020
reponame:Jornal Brasileiro de Nefrologia
instname:Sociedade Brasileira de Nefrologia (SBN)
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reponame_str Jornal Brasileiro de Nefrologia
collection Jornal Brasileiro de Nefrologia
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