Upper eyelid juvenile xanthogranuloma: a case report

• Autor(a) principal: Ribeiro,Pedro Henrique Oliveira
• Data de Publicação: 2021
• Outros Autores: Fritsch,Laura Nagy, Fernandes,Geraldo José Medeiros, Oliveira,Adriano Macedo de, Ribeiro,Flávia Beatriz de Andrade Oliveira
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista Brasileira de Oftalmologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000500500
• topic: Histiocytosis, Langerhans-cell; Xanthogranuloma, juvenile; Histiocytosis; Eyelid neoplasms

ABSTRACT Juvenile xanthogranuloma is a rare benign non-Langerhans cell histiocytosis. Clinical manifestation usually occurs up to the age of 2 years, with yellowish papules and variable clinical progression. Approximately 0.75% of patients had systemic involvement and 0.25%, ocular alterations. The purpose of this report is to describe a case of a preschool 2-year-old female patient, with nodules in the upper right eyelid, 0.5-cm wide, with well-defined edges, an uncertain date of onset, a stable growth for 6 months, with no inflammatory signs, pruritus, pain, bleeding, or other similar lesions in the body. No further changes were observed in the physical examination. Histopathological examination of the specimen showed a skin lesion with histiocytoid, spindle-shaped cells and xanthomized cells, inflammatory infiltrate and numerous Touton giant cells. The result was compatible with diagnosis of juvenile xanthogranuloma. Therefore, the importance of including juvenile xanthogranuloma in the differential diagnosis of eyelid lesions is emphasized, especially in children.