Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature

Detalhes bibliográficos
Autor(a) principal: Lopes Junior,Osmar Valadao
Data de Publicação: 2013
Outros Autores: Inacio,Andre Manoel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Ortopedia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162013000400300
Resumo: To evaluate the current evidence that support or disprove the use of glucosamine and chondroitin in the treatment of patients with osteoarthritis. We performed a literature review using the databases of Medline, PubMed and the Cochrane Controlled Trial Register and Cochrane Databases Systematic Reviews (Cochrane Library).We considered only studies with high level of evidence.The study included analysis of randomized controlled trials that included at least 100 patients in each intervention group, meta-analyzes and systematic reviews. Seven meta-analysis, one systematic review and five randomized clinical trials fit inclusion criteria of this review. Considering the best evidences until now, the use of glucosamine and chondroitin does not provide clinical relevant benefits to patients with osteoarthritis of the knee or hip (Level I of evidence and grade A of recommendation). Further trials with adequate technology are necessaries to elucidate this question.
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spelling Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literatureChondroitinGlucosamineOsteoarthritisReviewTo evaluate the current evidence that support or disprove the use of glucosamine and chondroitin in the treatment of patients with osteoarthritis. We performed a literature review using the databases of Medline, PubMed and the Cochrane Controlled Trial Register and Cochrane Databases Systematic Reviews (Cochrane Library).We considered only studies with high level of evidence.The study included analysis of randomized controlled trials that included at least 100 patients in each intervention group, meta-analyzes and systematic reviews. Seven meta-analysis, one systematic review and five randomized clinical trials fit inclusion criteria of this review. Considering the best evidences until now, the use of glucosamine and chondroitin does not provide clinical relevant benefits to patients with osteoarthritis of the knee or hip (Level I of evidence and grade A of recommendation). Further trials with adequate technology are necessaries to elucidate this question. Sociedade Brasileira de Ortopedia e Traumatologia2013-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162013000400300Revista Brasileira de Ortopedia v.48 n.4 2013reponame:Revista Brasileira de Ortopedia (Online)instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)instacron:SBOT10.1016/j.rbo.2012.09.007info:eu-repo/semantics/openAccessLopes Junior,Osmar ValadaoInacio,Andre Manoeleng2014-02-25T00:00:00Zoai:scielo:S0102-36162013000400300Revistahttp://www.rbo.org.br/https://old.scielo.br/oai/scielo-oai.php||rbo@sbot.org.br1982-43780102-3616opendoar:2014-02-25T00:00Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)false
dc.title.none.fl_str_mv Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
title Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
spellingShingle Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
Lopes Junior,Osmar Valadao
Chondroitin
Glucosamine
Osteoarthritis
Review
title_short Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
title_full Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
title_fullStr Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
title_full_unstemmed Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
title_sort Use of glucosamine and chondroitin to treat osteoarthritis: a review of the literature
author Lopes Junior,Osmar Valadao
author_facet Lopes Junior,Osmar Valadao
Inacio,Andre Manoel
author_role author
author2 Inacio,Andre Manoel
author2_role author
dc.contributor.author.fl_str_mv Lopes Junior,Osmar Valadao
Inacio,Andre Manoel
dc.subject.por.fl_str_mv Chondroitin
Glucosamine
Osteoarthritis
Review
topic Chondroitin
Glucosamine
Osteoarthritis
Review
description To evaluate the current evidence that support or disprove the use of glucosamine and chondroitin in the treatment of patients with osteoarthritis. We performed a literature review using the databases of Medline, PubMed and the Cochrane Controlled Trial Register and Cochrane Databases Systematic Reviews (Cochrane Library).We considered only studies with high level of evidence.The study included analysis of randomized controlled trials that included at least 100 patients in each intervention group, meta-analyzes and systematic reviews. Seven meta-analysis, one systematic review and five randomized clinical trials fit inclusion criteria of this review. Considering the best evidences until now, the use of glucosamine and chondroitin does not provide clinical relevant benefits to patients with osteoarthritis of the knee or hip (Level I of evidence and grade A of recommendation). Further trials with adequate technology are necessaries to elucidate this question.
publishDate 2013
dc.date.none.fl_str_mv 2013-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162013000400300
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162013000400300
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rbo.2012.09.007
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
dc.source.none.fl_str_mv Revista Brasileira de Ortopedia v.48 n.4 2013
reponame:Revista Brasileira de Ortopedia (Online)
instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron:SBOT
instname_str Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron_str SBOT
institution SBOT
reponame_str Revista Brasileira de Ortopedia (Online)
collection Revista Brasileira de Ortopedia (Online)
repository.name.fl_str_mv Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
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