Platelet-rich plasma (PRP) applied during total knee arthroplasty

Detalhes bibliográficos
Autor(a) principal: Guerreiro,João Paulo Fernandes
Data de Publicação: 2015
Outros Autores: Danieli,Marcus Vinicius, Queiroz,Alexandre Oliveira, Deffune,Elenice, Ferreira,Rosana Rossi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Brasileira de Ortopedia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162015000200186
Resumo: OBJECTIVE: To evaluate the efficacy of platelet-rich plasma regarding healing, pain and hemostasis after total knee arthroplasty, by means of a blinded randomized controlled and blinded clinical study.METHODS: Forty patients who were going to undergo implantation of a total knee prosthesis were selected and randomized. In 20 of these patients, platelet-rich plasma was applied before the joint capsule was closed. The hemoglobin (mg/dL) and hematocrit (%) levels were assayed before the operation and 24 and 48 h afterwards. The Womac questionnaire and a verbal pain scale were applied and knee range of motion measurements were made up to the second postoperative month. The statistical analysis compared the results with the aim of determining whether there were any differences between the groups at each of the evaluation times.RESULTS: The hemoglobin (mg/dL) and hematocrit (%) measurements made before the operation and 24 and 48 h afterwards did not show any significant differences between the groups (p > 0.05). The Womac questionnaire and the range of motion measured before the operation and up to the first two months also did not show any statistical differences between the groups (p > 0.05). The pain evaluation using the verbal scale showed that there was an advantage for the group that received platelet-rich plasma, 24 h, 48 h, one week, three weeks and two months after the operation (p < 0.05).CONCLUSIONS: In the manner in which the platelet-rich plasma was used, it was not shown to be effective for reducing bleeding or improving knee function after arthroplasty, in comparison with the controls. There was an advantage on the postoperative verbal pain scale.
id SBOT-2_d7f21b15a124a5c62f5d39fa8fe5d7cb
oai_identifier_str oai:scielo:S0102-36162015000200186
network_acronym_str SBOT-2
network_name_str Revista Brasileira de Ortopedia (Online)
repository_id_str
spelling Platelet-rich plasma (PRP) applied during total knee arthroplastyArthroplastyKneeTransfusionPlatelet-rich plasmaHemorrhageOBJECTIVE: To evaluate the efficacy of platelet-rich plasma regarding healing, pain and hemostasis after total knee arthroplasty, by means of a blinded randomized controlled and blinded clinical study.METHODS: Forty patients who were going to undergo implantation of a total knee prosthesis were selected and randomized. In 20 of these patients, platelet-rich plasma was applied before the joint capsule was closed. The hemoglobin (mg/dL) and hematocrit (%) levels were assayed before the operation and 24 and 48 h afterwards. The Womac questionnaire and a verbal pain scale were applied and knee range of motion measurements were made up to the second postoperative month. The statistical analysis compared the results with the aim of determining whether there were any differences between the groups at each of the evaluation times.RESULTS: The hemoglobin (mg/dL) and hematocrit (%) measurements made before the operation and 24 and 48 h afterwards did not show any significant differences between the groups (p > 0.05). The Womac questionnaire and the range of motion measured before the operation and up to the first two months also did not show any statistical differences between the groups (p > 0.05). The pain evaluation using the verbal scale showed that there was an advantage for the group that received platelet-rich plasma, 24 h, 48 h, one week, three weeks and two months after the operation (p < 0.05).CONCLUSIONS: In the manner in which the platelet-rich plasma was used, it was not shown to be effective for reducing bleeding or improving knee function after arthroplasty, in comparison with the controls. There was an advantage on the postoperative verbal pain scale.Sociedade Brasileira de Ortopedia e Traumatologia2015-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162015000200186Revista Brasileira de Ortopedia v.50 n.2 2015reponame:Revista Brasileira de Ortopedia (Online)instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)instacron:SBOT10.1016/j.rboe.2015.02.014info:eu-repo/semantics/openAccessGuerreiro,João Paulo FernandesDanieli,Marcus ViniciusQueiroz,Alexandre OliveiraDeffune,EleniceFerreira,Rosana Rossieng2015-09-10T00:00:00Zoai:scielo:S0102-36162015000200186Revistahttp://www.rbo.org.br/https://old.scielo.br/oai/scielo-oai.php||rbo@sbot.org.br1982-43780102-3616opendoar:2015-09-10T00:00Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)false
dc.title.none.fl_str_mv Platelet-rich plasma (PRP) applied during total knee arthroplasty
title Platelet-rich plasma (PRP) applied during total knee arthroplasty
spellingShingle Platelet-rich plasma (PRP) applied during total knee arthroplasty
Guerreiro,João Paulo Fernandes
Arthroplasty
Knee
Transfusion
Platelet-rich plasma
Hemorrhage
title_short Platelet-rich plasma (PRP) applied during total knee arthroplasty
title_full Platelet-rich plasma (PRP) applied during total knee arthroplasty
title_fullStr Platelet-rich plasma (PRP) applied during total knee arthroplasty
title_full_unstemmed Platelet-rich plasma (PRP) applied during total knee arthroplasty
title_sort Platelet-rich plasma (PRP) applied during total knee arthroplasty
author Guerreiro,João Paulo Fernandes
author_facet Guerreiro,João Paulo Fernandes
Danieli,Marcus Vinicius
Queiroz,Alexandre Oliveira
Deffune,Elenice
Ferreira,Rosana Rossi
author_role author
author2 Danieli,Marcus Vinicius
Queiroz,Alexandre Oliveira
Deffune,Elenice
Ferreira,Rosana Rossi
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Guerreiro,João Paulo Fernandes
Danieli,Marcus Vinicius
Queiroz,Alexandre Oliveira
Deffune,Elenice
Ferreira,Rosana Rossi
dc.subject.por.fl_str_mv Arthroplasty
Knee
Transfusion
Platelet-rich plasma
Hemorrhage
topic Arthroplasty
Knee
Transfusion
Platelet-rich plasma
Hemorrhage
description OBJECTIVE: To evaluate the efficacy of platelet-rich plasma regarding healing, pain and hemostasis after total knee arthroplasty, by means of a blinded randomized controlled and blinded clinical study.METHODS: Forty patients who were going to undergo implantation of a total knee prosthesis were selected and randomized. In 20 of these patients, platelet-rich plasma was applied before the joint capsule was closed. The hemoglobin (mg/dL) and hematocrit (%) levels were assayed before the operation and 24 and 48 h afterwards. The Womac questionnaire and a verbal pain scale were applied and knee range of motion measurements were made up to the second postoperative month. The statistical analysis compared the results with the aim of determining whether there were any differences between the groups at each of the evaluation times.RESULTS: The hemoglobin (mg/dL) and hematocrit (%) measurements made before the operation and 24 and 48 h afterwards did not show any significant differences between the groups (p > 0.05). The Womac questionnaire and the range of motion measured before the operation and up to the first two months also did not show any statistical differences between the groups (p > 0.05). The pain evaluation using the verbal scale showed that there was an advantage for the group that received platelet-rich plasma, 24 h, 48 h, one week, three weeks and two months after the operation (p < 0.05).CONCLUSIONS: In the manner in which the platelet-rich plasma was used, it was not shown to be effective for reducing bleeding or improving knee function after arthroplasty, in comparison with the controls. There was an advantage on the postoperative verbal pain scale.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162015000200186
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162015000200186
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.rboe.2015.02.014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
publisher.none.fl_str_mv Sociedade Brasileira de Ortopedia e Traumatologia
dc.source.none.fl_str_mv Revista Brasileira de Ortopedia v.50 n.2 2015
reponame:Revista Brasileira de Ortopedia (Online)
instname:Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron:SBOT
instname_str Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
instacron_str SBOT
institution SBOT
reponame_str Revista Brasileira de Ortopedia (Online)
collection Revista Brasileira de Ortopedia (Online)
repository.name.fl_str_mv Revista Brasileira de Ortopedia (Online) - Sociedade Brasileira de Ortopedia e Traumatologia (SBOT)
repository.mail.fl_str_mv ||rbo@sbot.org.br
_version_ 1752122359634984960