Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations

Detalhes bibliográficos
Autor(a) principal: Cambruzzi,Eduardo
Data de Publicação: 2013
Outros Autores: Pêgas,Karla Lais, Silveira,Luciano Carvalho
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000200011
Resumo: Pilocytic astrocytoma (PA) is a grade I glial neoplasm arising mainly in the cerebellum of children. Herein, the authors report a case of PA in a 21 year-old male patient, who presented headache, vomiting and delayed pubertal development. Serum level of cortisol and testosterone corresponded to 32.8 ug/dl and 0.19 ng/ml, respectively. The computed tomography/magnetic resonance (CT/RM) imaging showed an expansive process compromising suprasellar/hypothalamic region and determining hydrocephalus. The patient underwent resection of the process. Histological evaluation revealed a glial neoplasm constituted by loose glial tissue, small microcysts, areas of dense piloid tissue and Rosenthal fibers. The neoplastic cells were immunoreactive for glial fibrillary acidic protein (GFAP) and negative for chromogranin and synaptophysin. The diagnosis of PA was then established.
id SBP-1_84190d8f57f23539dbb7a8080dc5eb1e
oai_identifier_str oai:scielo:S1676-24442013000200011
network_acronym_str SBP-1
network_name_str Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
repository_id_str
spelling Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestationspilocytic astrocytomacentral nervous system neoplasmspathologybrain neoplasmsendocrine diseasesPilocytic astrocytoma (PA) is a grade I glial neoplasm arising mainly in the cerebellum of children. Herein, the authors report a case of PA in a 21 year-old male patient, who presented headache, vomiting and delayed pubertal development. Serum level of cortisol and testosterone corresponded to 32.8 ug/dl and 0.19 ng/ml, respectively. The computed tomography/magnetic resonance (CT/RM) imaging showed an expansive process compromising suprasellar/hypothalamic region and determining hydrocephalus. The patient underwent resection of the process. Histological evaluation revealed a glial neoplasm constituted by loose glial tissue, small microcysts, areas of dense piloid tissue and Rosenthal fibers. The neoplastic cells were immunoreactive for glial fibrillary acidic protein (GFAP) and negative for chromogranin and synaptophysin. The diagnosis of PA was then established.Sociedade Brasileira de Patologia Clínica2013-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000200011Jornal Brasileiro de Patologia e Medicina Laboratorial v.49 n.2 2013reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)instname:Sociedade Brasileira de Patologia (SBP)instacron:SBP10.1590/S1676-24442013000200011info:eu-repo/semantics/openAccessCambruzzi,EduardoPêgas,Karla LaisSilveira,Luciano Carvalhoeng2013-06-24T00:00:00Zoai:scielo:S1676-24442013000200011Revistahttp://www.scielo.br/jbpmlhttps://old.scielo.br/oai/scielo-oai.php||jbpml@sbpc.org.br1678-47741676-2444opendoar:2013-06-24T00:00Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)false
dc.title.none.fl_str_mv Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
title Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
spellingShingle Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
Cambruzzi,Eduardo
pilocytic astrocytoma
central nervous system neoplasms
pathology
brain neoplasms
endocrine diseases
title_short Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
title_full Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
title_fullStr Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
title_full_unstemmed Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
title_sort Pilocytic astrocytoma of sellar/suprasellar region determining endocrine manifestations
author Cambruzzi,Eduardo
author_facet Cambruzzi,Eduardo
Pêgas,Karla Lais
Silveira,Luciano Carvalho
author_role author
author2 Pêgas,Karla Lais
Silveira,Luciano Carvalho
author2_role author
author
dc.contributor.author.fl_str_mv Cambruzzi,Eduardo
Pêgas,Karla Lais
Silveira,Luciano Carvalho
dc.subject.por.fl_str_mv pilocytic astrocytoma
central nervous system neoplasms
pathology
brain neoplasms
endocrine diseases
topic pilocytic astrocytoma
central nervous system neoplasms
pathology
brain neoplasms
endocrine diseases
description Pilocytic astrocytoma (PA) is a grade I glial neoplasm arising mainly in the cerebellum of children. Herein, the authors report a case of PA in a 21 year-old male patient, who presented headache, vomiting and delayed pubertal development. Serum level of cortisol and testosterone corresponded to 32.8 ug/dl and 0.19 ng/ml, respectively. The computed tomography/magnetic resonance (CT/RM) imaging showed an expansive process compromising suprasellar/hypothalamic region and determining hydrocephalus. The patient underwent resection of the process. Histological evaluation revealed a glial neoplasm constituted by loose glial tissue, small microcysts, areas of dense piloid tissue and Rosenthal fibers. The neoplastic cells were immunoreactive for glial fibrillary acidic protein (GFAP) and negative for chromogranin and synaptophysin. The diagnosis of PA was then established.
publishDate 2013
dc.date.none.fl_str_mv 2013-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000200011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000200011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1676-24442013000200011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv
Sociedade Brasileira de Patologia Clínica
publisher.none.fl_str_mv
Sociedade Brasileira de Patologia Clínica
dc.source.none.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial v.49 n.2 2013
reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
instname:Sociedade Brasileira de Patologia (SBP)
instacron:SBP
instname_str Sociedade Brasileira de Patologia (SBP)
instacron_str SBP
institution SBP
reponame_str Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
collection Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
repository.name.fl_str_mv Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)
repository.mail.fl_str_mv ||jbpml@sbpc.org.br
_version_ 1752122295835426816

Registros relacionados