Lung cancer biomarkers. A literature review
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100300 |
Resumo: | ABSTRACT Lung cancer is the first in terms of incidence and mortality, being responsible worldwide for about 1.8 million deaths. In Brazil 31,270 new cases were diagnosed in 2018, 18,740 in men and 12,350 in women. One of the main challenges about lung cancer is performing an early diagnosis, in most cases the disease is detected in the late stages, which implies in poor prognoses. Tumor biomarkers are hugely relevant in early diagnosis, understanding of carcinogenesis, prognostic determination and therapeutic choice. The present paper reviews non-small cell lung cancer biomarkers described in the literature and their diagnostic, prognostic and therapeutic applications, intervention and therapeutic control for individualized therapy. Although there is still a vast universe to be explored, studies reveal a promising future for lung cancer treatment with increasingly personalized and assertive therapies that increase the chances of progression-free survival. |
id |
SBP-1_d477835ec3782687c25c5d7bca76b7fc |
---|---|
oai_identifier_str |
oai:scielo:S1676-24442022000100300 |
network_acronym_str |
SBP-1 |
network_name_str |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
repository_id_str |
|
spelling |
Lung cancer biomarkers. A literature reviewlung neoplasmsbiomarkerstumorhumansABSTRACT Lung cancer is the first in terms of incidence and mortality, being responsible worldwide for about 1.8 million deaths. In Brazil 31,270 new cases were diagnosed in 2018, 18,740 in men and 12,350 in women. One of the main challenges about lung cancer is performing an early diagnosis, in most cases the disease is detected in the late stages, which implies in poor prognoses. Tumor biomarkers are hugely relevant in early diagnosis, understanding of carcinogenesis, prognostic determination and therapeutic choice. The present paper reviews non-small cell lung cancer biomarkers described in the literature and their diagnostic, prognostic and therapeutic applications, intervention and therapeutic control for individualized therapy. Although there is still a vast universe to be explored, studies reveal a promising future for lung cancer treatment with increasingly personalized and assertive therapies that increase the chances of progression-free survival.Sociedade Brasileira de Patologia Clínica2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100300Jornal Brasileiro de Patologia e Medicina Laboratorial v.58 2022reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)instname:Sociedade Brasileira de Patologia (SBP)instacron:SBP10.1900/jbpml.2022.58.415info:eu-repo/semantics/openAccessSoares Costa,Amanda AngeloVeiga,Glaucia Luciano daAlves,Beatriz da Costa AguiarGascón,Thaís MouraPereira,Edimar CristianoAzzalis,Ligia AjaimeFonseca,Fernando Luiz Affonsoeng2022-05-26T00:00:00Zoai:scielo:S1676-24442022000100300Revistahttp://www.scielo.br/jbpmlhttps://old.scielo.br/oai/scielo-oai.php||jbpml@sbpc.org.br1678-47741676-2444opendoar:2022-05-26T00:00Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP)false |
dc.title.none.fl_str_mv |
Lung cancer biomarkers. A literature review |
title |
Lung cancer biomarkers. A literature review |
spellingShingle |
Lung cancer biomarkers. A literature review Soares Costa,Amanda Angelo lung neoplasms biomarkers tumor humans |
title_short |
Lung cancer biomarkers. A literature review |
title_full |
Lung cancer biomarkers. A literature review |
title_fullStr |
Lung cancer biomarkers. A literature review |
title_full_unstemmed |
Lung cancer biomarkers. A literature review |
title_sort |
Lung cancer biomarkers. A literature review |
author |
Soares Costa,Amanda Angelo |
author_facet |
Soares Costa,Amanda Angelo Veiga,Glaucia Luciano da Alves,Beatriz da Costa Aguiar Gascón,Thaís Moura Pereira,Edimar Cristiano Azzalis,Ligia Ajaime Fonseca,Fernando Luiz Affonso |
author_role |
author |
author2 |
Veiga,Glaucia Luciano da Alves,Beatriz da Costa Aguiar Gascón,Thaís Moura Pereira,Edimar Cristiano Azzalis,Ligia Ajaime Fonseca,Fernando Luiz Affonso |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Soares Costa,Amanda Angelo Veiga,Glaucia Luciano da Alves,Beatriz da Costa Aguiar Gascón,Thaís Moura Pereira,Edimar Cristiano Azzalis,Ligia Ajaime Fonseca,Fernando Luiz Affonso |
dc.subject.por.fl_str_mv |
lung neoplasms biomarkers tumor humans |
topic |
lung neoplasms biomarkers tumor humans |
description |
ABSTRACT Lung cancer is the first in terms of incidence and mortality, being responsible worldwide for about 1.8 million deaths. In Brazil 31,270 new cases were diagnosed in 2018, 18,740 in men and 12,350 in women. One of the main challenges about lung cancer is performing an early diagnosis, in most cases the disease is detected in the late stages, which implies in poor prognoses. Tumor biomarkers are hugely relevant in early diagnosis, understanding of carcinogenesis, prognostic determination and therapeutic choice. The present paper reviews non-small cell lung cancer biomarkers described in the literature and their diagnostic, prognostic and therapeutic applications, intervention and therapeutic control for individualized therapy. Although there is still a vast universe to be explored, studies reveal a promising future for lung cancer treatment with increasingly personalized and assertive therapies that increase the chances of progression-free survival. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100300 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442022000100300 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1900/jbpml.2022.58.415 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Patologia Clínica |
publisher.none.fl_str_mv |
Sociedade Brasileira de Patologia Clínica |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Patologia e Medicina Laboratorial v.58 2022 reponame:Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) instname:Sociedade Brasileira de Patologia (SBP) instacron:SBP |
instname_str |
Sociedade Brasileira de Patologia (SBP) |
instacron_str |
SBP |
institution |
SBP |
reponame_str |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
collection |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) - Sociedade Brasileira de Patologia (SBP) |
repository.mail.fl_str_mv |
||jbpml@sbpc.org.br |
_version_ |
1752122297916850176 |