Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal de Pediatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500520 |
Resumo: | Abstract Objective: To evaluate cardiac function and structural changes in children of diabetic mothers in the fetal and neonatal period using Doppler-echocardiographic data. Method: A prospective, descriptive observational study conducted in a private and tertiary care service for high-risk pregnant women. It included 48 children of mothers with gestational diabetes mellitus (GDM) considered clinically compensated during pregnancy, with a single fetus and absence of malformations. Myocardial thickness, shortening fraction, left ventricular (LVMPI) and right ventricular (RVMPI) myocardial performance index, and mitral and tricuspid valve E/A ratio were evaluated in 96 echocardiographic exams with Doppler. Results: The hypertrophic cardiomyopathy was 29% vs 6% p = 0.006 in the prenatal and postnatal periods respectively. The shortening fraction was 0% vs 6% p = 0.242 in the fetuses and newborns respectively. The myocardial performance index of the right ventricle was 12% vs 54% p ≤ 0.001, and on the left ventricle 27% vs 60% p = 0.001 in the prenatal and postnatal periods respectively. The ratio of mitral valve E/A waves was 6% vs 50% p ≤ 0.001 and the ratio of tricuspid valve E/A waves was 0% vs 27% p 0.001 in the fetuses and newborns respectively. Conclusion: A decrease in the rate of myocardial hypertrophy and changes in cardiac function parameters were observed in the fetal and neonatal periods. |
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Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothersGestational diabetesHypertrophic cardiomyopathyDoppler echocardiographyFetal heartNewborn healthAbstract Objective: To evaluate cardiac function and structural changes in children of diabetic mothers in the fetal and neonatal period using Doppler-echocardiographic data. Method: A prospective, descriptive observational study conducted in a private and tertiary care service for high-risk pregnant women. It included 48 children of mothers with gestational diabetes mellitus (GDM) considered clinically compensated during pregnancy, with a single fetus and absence of malformations. Myocardial thickness, shortening fraction, left ventricular (LVMPI) and right ventricular (RVMPI) myocardial performance index, and mitral and tricuspid valve E/A ratio were evaluated in 96 echocardiographic exams with Doppler. Results: The hypertrophic cardiomyopathy was 29% vs 6% p = 0.006 in the prenatal and postnatal periods respectively. The shortening fraction was 0% vs 6% p = 0.242 in the fetuses and newborns respectively. The myocardial performance index of the right ventricle was 12% vs 54% p ≤ 0.001, and on the left ventricle 27% vs 60% p = 0.001 in the prenatal and postnatal periods respectively. The ratio of mitral valve E/A waves was 6% vs 50% p ≤ 0.001 and the ratio of tricuspid valve E/A waves was 0% vs 27% p 0.001 in the fetuses and newborns respectively. Conclusion: A decrease in the rate of myocardial hypertrophy and changes in cardiac function parameters were observed in the fetal and neonatal periods.Sociedade Brasileira de Pediatria2021-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500520Jornal de Pediatria v.97 n.5 2021reponame:Jornal de Pediatria (Online)instname:Sociedade Brasileira de Pediatria (SBP)instacron:SBPE10.1016/j.jped.2020.10.003info:eu-repo/semantics/openAccessBogo,Maria AugustaPabis,Julia SBonchoski,Ana BSantos,Dercília C. dosPinto,Tainá J.FSimões,Mona ASilva,Jean CPabis,Francisco Ceng2021-10-08T00:00:00Zoai:scielo:S0021-75572021000500520Revistahttp://www.jped.com.br/https://old.scielo.br/oai/scielo-oai.php||jped@jped.com.br1678-47820021-7557opendoar:2021-10-08T00:00Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)false |
dc.title.none.fl_str_mv |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
title |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
spellingShingle |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers Bogo,Maria Augusta Gestational diabetes Hypertrophic cardiomyopathy Doppler echocardiography Fetal heart Newborn health |
title_short |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
title_full |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
title_fullStr |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
title_full_unstemmed |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
title_sort |
Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers |
author |
Bogo,Maria Augusta |
author_facet |
Bogo,Maria Augusta Pabis,Julia S Bonchoski,Ana B Santos,Dercília C. dos Pinto,Tainá J.F Simões,Mona A Silva,Jean C Pabis,Francisco C |
author_role |
author |
author2 |
Pabis,Julia S Bonchoski,Ana B Santos,Dercília C. dos Pinto,Tainá J.F Simões,Mona A Silva,Jean C Pabis,Francisco C |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Bogo,Maria Augusta Pabis,Julia S Bonchoski,Ana B Santos,Dercília C. dos Pinto,Tainá J.F Simões,Mona A Silva,Jean C Pabis,Francisco C |
dc.subject.por.fl_str_mv |
Gestational diabetes Hypertrophic cardiomyopathy Doppler echocardiography Fetal heart Newborn health |
topic |
Gestational diabetes Hypertrophic cardiomyopathy Doppler echocardiography Fetal heart Newborn health |
description |
Abstract Objective: To evaluate cardiac function and structural changes in children of diabetic mothers in the fetal and neonatal period using Doppler-echocardiographic data. Method: A prospective, descriptive observational study conducted in a private and tertiary care service for high-risk pregnant women. It included 48 children of mothers with gestational diabetes mellitus (GDM) considered clinically compensated during pregnancy, with a single fetus and absence of malformations. Myocardial thickness, shortening fraction, left ventricular (LVMPI) and right ventricular (RVMPI) myocardial performance index, and mitral and tricuspid valve E/A ratio were evaluated in 96 echocardiographic exams with Doppler. Results: The hypertrophic cardiomyopathy was 29% vs 6% p = 0.006 in the prenatal and postnatal periods respectively. The shortening fraction was 0% vs 6% p = 0.242 in the fetuses and newborns respectively. The myocardial performance index of the right ventricle was 12% vs 54% p ≤ 0.001, and on the left ventricle 27% vs 60% p = 0.001 in the prenatal and postnatal periods respectively. The ratio of mitral valve E/A waves was 6% vs 50% p ≤ 0.001 and the ratio of tricuspid valve E/A waves was 0% vs 27% p 0.001 in the fetuses and newborns respectively. Conclusion: A decrease in the rate of myocardial hypertrophy and changes in cardiac function parameters were observed in the fetal and neonatal periods. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500520 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572021000500520 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jped.2020.10.003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
dc.source.none.fl_str_mv |
Jornal de Pediatria v.97 n.5 2021 reponame:Jornal de Pediatria (Online) instname:Sociedade Brasileira de Pediatria (SBP) instacron:SBPE |
instname_str |
Sociedade Brasileira de Pediatria (SBP) |
instacron_str |
SBPE |
institution |
SBPE |
reponame_str |
Jornal de Pediatria (Online) |
collection |
Jornal de Pediatria (Online) |
repository.name.fl_str_mv |
Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP) |
repository.mail.fl_str_mv |
||jped@jped.com.br |
_version_ |
1752122322811092992 |