Frequency of and factors associated with vascular complications after pediatric liver transplantation ,

Detalhes bibliográficos
Autor(a) principal: Orlandini,Mariana
Data de Publicação: 2014
Outros Autores: Feier,Flávia Heinz, Jaeger,Brunna, Kieling,Carlos, Vieira,Sandra Gonçalves, Zanotelli,Maria Lucia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal de Pediatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572014000200169
Resumo: OBJECTIVE:to evaluate the frequency and factors associated with vascular complications after pediatric liver transplantation.METHOD:risk factors were evaluated in 99 patients under 18 years of age with chronic liver disease who underwent deceased donor liver transplantation (DDLT) between March of 1995 and November of 2009 at the Hospital de Clínicas de Porto Alegre, Brazil. The variables analyzed included donor and recipient age, gender, and weight; indication for transplant; PELD/MELD scores; technical aspects; postoperative vascular complications; and survival.RESULTS:vascular complications occurred in 19 patients (19%). Arterial events were most common, occurred earlier in the postoperative period, and were associated with high graft loss and mortality rates. In the multivariate analysis, the following factors were identified: portal vein diameter < 3 mm, donor-to-recipient body weight ratio (DRWR), prolonged ischemic time, and use of arterial grafts.CONCLUSION:the choice of treatment depends on the timing of diagnosis; however, in this study, surgical revision or correction produced worse outcomes than percutaneous angioplasty. The reduction of risk factors and early detection of vascular complications are key elements to a successful transplantation.
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spelling Frequency of and factors associated with vascular complications after pediatric liver transplantation ,ThrombosisHepatic arteryPortal veinMorbidityMortalityOBJECTIVE:to evaluate the frequency and factors associated with vascular complications after pediatric liver transplantation.METHOD:risk factors were evaluated in 99 patients under 18 years of age with chronic liver disease who underwent deceased donor liver transplantation (DDLT) between March of 1995 and November of 2009 at the Hospital de Clínicas de Porto Alegre, Brazil. The variables analyzed included donor and recipient age, gender, and weight; indication for transplant; PELD/MELD scores; technical aspects; postoperative vascular complications; and survival.RESULTS:vascular complications occurred in 19 patients (19%). Arterial events were most common, occurred earlier in the postoperative period, and were associated with high graft loss and mortality rates. In the multivariate analysis, the following factors were identified: portal vein diameter < 3 mm, donor-to-recipient body weight ratio (DRWR), prolonged ischemic time, and use of arterial grafts.CONCLUSION:the choice of treatment depends on the timing of diagnosis; however, in this study, surgical revision or correction produced worse outcomes than percutaneous angioplasty. The reduction of risk factors and early detection of vascular complications are key elements to a successful transplantation.Sociedade Brasileira de Pediatria2014-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572014000200169Jornal de Pediatria v.90 n.2 2014reponame:Jornal de Pediatria (Online)instname:Sociedade Brasileira de Pediatria (SBP)instacron:SBPE10.1016/j.jped.2013.08.010info:eu-repo/semantics/openAccessOrlandini,MarianaFeier,Flávia HeinzJaeger,BrunnaKieling,CarlosVieira,Sandra GonçalvesZanotelli,Maria Luciaeng2015-10-08T00:00:00Zoai:scielo:S0021-75572014000200169Revistahttp://www.jped.com.br/https://old.scielo.br/oai/scielo-oai.php||jped@jped.com.br1678-47820021-7557opendoar:2015-10-08T00:00Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)false
dc.title.none.fl_str_mv Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
title Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
spellingShingle Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
Orlandini,Mariana
Thrombosis
Hepatic artery
Portal vein
Morbidity
Mortality
title_short Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
title_full Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
title_fullStr Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
title_full_unstemmed Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
title_sort Frequency of and factors associated with vascular complications after pediatric liver transplantation ,
author Orlandini,Mariana
author_facet Orlandini,Mariana
Feier,Flávia Heinz
Jaeger,Brunna
Kieling,Carlos
Vieira,Sandra Gonçalves
Zanotelli,Maria Lucia
author_role author
author2 Feier,Flávia Heinz
Jaeger,Brunna
Kieling,Carlos
Vieira,Sandra Gonçalves
Zanotelli,Maria Lucia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Orlandini,Mariana
Feier,Flávia Heinz
Jaeger,Brunna
Kieling,Carlos
Vieira,Sandra Gonçalves
Zanotelli,Maria Lucia
dc.subject.por.fl_str_mv Thrombosis
Hepatic artery
Portal vein
Morbidity
Mortality
topic Thrombosis
Hepatic artery
Portal vein
Morbidity
Mortality
description OBJECTIVE:to evaluate the frequency and factors associated with vascular complications after pediatric liver transplantation.METHOD:risk factors were evaluated in 99 patients under 18 years of age with chronic liver disease who underwent deceased donor liver transplantation (DDLT) between March of 1995 and November of 2009 at the Hospital de Clínicas de Porto Alegre, Brazil. The variables analyzed included donor and recipient age, gender, and weight; indication for transplant; PELD/MELD scores; technical aspects; postoperative vascular complications; and survival.RESULTS:vascular complications occurred in 19 patients (19%). Arterial events were most common, occurred earlier in the postoperative period, and were associated with high graft loss and mortality rates. In the multivariate analysis, the following factors were identified: portal vein diameter < 3 mm, donor-to-recipient body weight ratio (DRWR), prolonged ischemic time, and use of arterial grafts.CONCLUSION:the choice of treatment depends on the timing of diagnosis; however, in this study, surgical revision or correction produced worse outcomes than percutaneous angioplasty. The reduction of risk factors and early detection of vascular complications are key elements to a successful transplantation.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572014000200169
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572014000200169
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.jped.2013.08.010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pediatria
publisher.none.fl_str_mv Sociedade Brasileira de Pediatria
dc.source.none.fl_str_mv Jornal de Pediatria v.90 n.2 2014
reponame:Jornal de Pediatria (Online)
instname:Sociedade Brasileira de Pediatria (SBP)
instacron:SBPE
instname_str Sociedade Brasileira de Pediatria (SBP)
instacron_str SBPE
institution SBPE
reponame_str Jornal de Pediatria (Online)
collection Jornal de Pediatria (Online)
repository.name.fl_str_mv Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)
repository.mail.fl_str_mv ||jped@jped.com.br
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