Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits

Detalhes bibliográficos
Autor(a) principal: Molina-Miñano,Francisco
Data de Publicação: 2009
Outros Autores: López-Jornet,Pía, Camacho-Alonso,Fabio, Vicente-Ortega,Vicente
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000300009
Resumo: A radiographic and histomorphometric study was conducted on the influence of autologous plasma rich in growth factors (PRGF) upon bone healing in surgically created defects in rabbits. Radiographically, bone regeneration was significantly greater with the use of PRGF after one month (p = 0.005), though no differences were recorded after the second month. In the histomorphometric analysis one month after surgery, the defects filled with autologous bone plus PRGF showed a greater percentage of neoformed bone (35.01 ± 5.31) than the control defects (22.90 ± 12.23), though the differences were not significant. Two months after surgery, the defects filled with autologous bone showed greater regeneration (46.04 ± 10.36%) than the control defects (30.59 ± 5.69%), though the differences were not significant. The application of PRGF in the bone defects produced in New Zealand rabbits exerted a limited effect on local bone formation.
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spelling Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbitsBone and bonesIntercellular signaling peptides and proteinsRabbitsRadiographyHistologyA radiographic and histomorphometric study was conducted on the influence of autologous plasma rich in growth factors (PRGF) upon bone healing in surgically created defects in rabbits. Radiographically, bone regeneration was significantly greater with the use of PRGF after one month (p = 0.005), though no differences were recorded after the second month. In the histomorphometric analysis one month after surgery, the defects filled with autologous bone plus PRGF showed a greater percentage of neoformed bone (35.01 ± 5.31) than the control defects (22.90 ± 12.23), though the differences were not significant. Two months after surgery, the defects filled with autologous bone showed greater regeneration (46.04 ± 10.36%) than the control defects (30.59 ± 5.69%), though the differences were not significant. The application of PRGF in the bone defects produced in New Zealand rabbits exerted a limited effect on local bone formation.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000300009Brazilian Oral Research v.23 n.3 2009reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242009000300009info:eu-repo/semantics/openAccessMolina-Miñano,FranciscoLópez-Jornet,PíaCamacho-Alonso,FabioVicente-Ortega,Vicenteeng2009-11-04T00:00:00Zoai:scielo:S1806-83242009000300009Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2009-11-04T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
title Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
spellingShingle Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
Molina-Miñano,Francisco
Bone and bones
Intercellular signaling peptides and proteins
Rabbits
Radiography
Histology
title_short Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
title_full Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
title_fullStr Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
title_full_unstemmed Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
title_sort Plasma rich in growth factors and bone formation: a radiological and histomorphometric study in New Zealand rabbits
author Molina-Miñano,Francisco
author_facet Molina-Miñano,Francisco
López-Jornet,Pía
Camacho-Alonso,Fabio
Vicente-Ortega,Vicente
author_role author
author2 López-Jornet,Pía
Camacho-Alonso,Fabio
Vicente-Ortega,Vicente
author2_role author
author
author
dc.contributor.author.fl_str_mv Molina-Miñano,Francisco
López-Jornet,Pía
Camacho-Alonso,Fabio
Vicente-Ortega,Vicente
dc.subject.por.fl_str_mv Bone and bones
Intercellular signaling peptides and proteins
Rabbits
Radiography
Histology
topic Bone and bones
Intercellular signaling peptides and proteins
Rabbits
Radiography
Histology
description A radiographic and histomorphometric study was conducted on the influence of autologous plasma rich in growth factors (PRGF) upon bone healing in surgically created defects in rabbits. Radiographically, bone regeneration was significantly greater with the use of PRGF after one month (p = 0.005), though no differences were recorded after the second month. In the histomorphometric analysis one month after surgery, the defects filled with autologous bone plus PRGF showed a greater percentage of neoformed bone (35.01 ± 5.31) than the control defects (22.90 ± 12.23), though the differences were not significant. Two months after surgery, the defects filled with autologous bone showed greater regeneration (46.04 ± 10.36%) than the control defects (30.59 ± 5.69%), though the differences were not significant. The application of PRGF in the bone defects produced in New Zealand rabbits exerted a limited effect on local bone formation.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000300009
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242009000300009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242009000300009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.23 n.3 2009
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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