Effect of gamma rays on the bone repair process in rats with estrogen deficiency

Detalhes bibliográficos
Autor(a) principal: Chicarelli,Mariliani
Data de Publicação: 2007
Outros Autores: Ramos,Flávia Maria de Moraes, Manzi,Flávio Ricardo, Novaes,Pedro Duarte, Bóscolo,Frab Norberto, Almeida,Solange Maria de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013
Resumo: This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.
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spelling Effect of gamma rays on the bone repair process in rats with estrogen deficiencyEstrogensOsteoporosisOvariectomyBone and bonesFracture healingThis study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013Brazilian Oral Research v.21 n.1 2007reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/S1806-83242007000100013info:eu-repo/semantics/openAccessChicarelli,MarilianiRamos,Flávia Maria de MoraesManzi,Flávio RicardoNovaes,Pedro DuarteBóscolo,Frab NorbertoAlmeida,Solange Maria deeng2007-03-23T00:00:00Zoai:scielo:S1806-83242007000100013Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2007-03-23T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv Effect of gamma rays on the bone repair process in rats with estrogen deficiency
title Effect of gamma rays on the bone repair process in rats with estrogen deficiency
spellingShingle Effect of gamma rays on the bone repair process in rats with estrogen deficiency
Chicarelli,Mariliani
Estrogens
Osteoporosis
Ovariectomy
Bone and bones
Fracture healing
title_short Effect of gamma rays on the bone repair process in rats with estrogen deficiency
title_full Effect of gamma rays on the bone repair process in rats with estrogen deficiency
title_fullStr Effect of gamma rays on the bone repair process in rats with estrogen deficiency
title_full_unstemmed Effect of gamma rays on the bone repair process in rats with estrogen deficiency
title_sort Effect of gamma rays on the bone repair process in rats with estrogen deficiency
author Chicarelli,Mariliani
author_facet Chicarelli,Mariliani
Ramos,Flávia Maria de Moraes
Manzi,Flávio Ricardo
Novaes,Pedro Duarte
Bóscolo,Frab Norberto
Almeida,Solange Maria de
author_role author
author2 Ramos,Flávia Maria de Moraes
Manzi,Flávio Ricardo
Novaes,Pedro Duarte
Bóscolo,Frab Norberto
Almeida,Solange Maria de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Chicarelli,Mariliani
Ramos,Flávia Maria de Moraes
Manzi,Flávio Ricardo
Novaes,Pedro Duarte
Bóscolo,Frab Norberto
Almeida,Solange Maria de
dc.subject.por.fl_str_mv Estrogens
Osteoporosis
Ovariectomy
Bone and bones
Fracture healing
topic Estrogens
Osteoporosis
Ovariectomy
Bone and bones
Fracture healing
description This study aimed at evaluating the bone repair process in ovariectomized rats submitted to an irradiation procedure. For this purpose, one hundred rats were randomly divided in four experimental groups: control, ovariectomized, irradiated and irradiated/ovariectomized. A bone defect was made on all animals' tibias. Three days after surgery, only irradiated and irradiated/ovariectomized rats received 8 Gy of gamma rays on the lower limbs region. The animals were sacrificed 7, 14, 21 and 28 days after surgery in order to assess the repair process. It was possible to observe a delay in the bone repair process in the irradiated/ovariectomized group, in which there was a remarkable association between estrogen deficiency and ionizing radiation resulting in the reduction of newly formed bone production, thus accelerating the resorption process.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242007000100013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1806-83242007000100013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.21 n.1 2007
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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